Molecular Order of Ceramide Trihexoside (CTH) Inclusions of Fabry’s Disease: Study Through Digital Image Processing and Optical Fourier Transformation
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Since 1979, the structure of various biological membranes has been studied at the G.A.I.B. using optical means. In case the membrane elements are stacked together into lamellar thick inclusions a favourable statistical situation arises. In case of Fabry’s disease such inclusions can be found in several tissues and organs, including heart and kidney. This disease is caused by an enzymatic α-galactosidase A deficiency, which is X-chromosome linked, and is quickly mortal to men (45 years). The inclusions consist of ceramide trihexoside molecules and water .
KeywordsImage Processing Technique Membrane Element Repeat Distance Comptes Rendus Acad Period Histogram
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