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Molecular Order of Ceramide Trihexoside (CTH) Inclusions of Fabry’s Disease: Study Through Digital Image Processing and Optical Fourier Transformation

  • F. Delbarre
  • S. Laoussadi
  • H. Dupoisot
  • A. Constans
  • G. Daury
Conference paper
  • 205 Downloads
Part of the Springer Series in Optical Sciences book series (SSOS, volume 31)

Abstract

Since 1979, the structure of various biological membranes has been studied at the G.A.I.B. using optical means. In case the membrane elements are stacked together into lamellar thick inclusions a favourable statistical situation arises. In case of Fabry’s disease such inclusions can be found in several tissues and organs, including heart and kidney. This disease is caused by an enzymatic α-galactosidase A deficiency, which is X-chromosome linked, and is quickly mortal to men (45 years). The inclusions consist of ceramide trihexoside molecules and water [1].

Keywords

Image Processing Technique Membrane Element Repeat Distance Comptes Rendus Acad Period Histogram 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Sweeley, C.; Klionsky, B.; Krivit, W.; Desnier, R.; in Wyngaarden, J.; Stanbury, J.; Frederickson, D.: The Metabolic Basis of Inherited Diseases, Third Ed., McGraw Hill, N-Y, (1972) p. 663.Google Scholar
  2. 2.
    Tardieu, A.: Etude cristallographique de systèmes lipides-eau. Thèse de Doctorat ès Sciences, Paris-Sud, (21/3/1972), n 915, Série A, 122 p.Google Scholar
  3. 3.
    Dupoisot, H.; Constans, A.; Daury, G.; Delbarre, F.; Laoussadi, S.: Comptes Rendus Acad. Sc., (Paris), (1979), 288 D, p. 783.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • F. Delbarre
    • 1
  • S. Laoussadi
    • 1
  • H. Dupoisot
    • 1
  • A. Constans
    • 1
  • G. Daury
    • 1
  1. 1.Groupe d’Analyse d’Images BiomédicalesUniversité René Descartes 3ParisFrance

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