Abstract
A study is made of the laser-induced fluorescence properties of the complex formed by Quinacrine Mustard bound to Deoxyribonucleic Acid (DNA). Specific information is obtained on the binding mechanisms and on the base-pair sequences of the DNA. The relevance of these measurements in several fields from chemical physics to biology and medecine is discussed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
See, for example, Laser in Physical Chemistry and Biophysics ed. by J.Joussot-Dubien (Elsevier Scientific Publ.Co.,Amster dam, 1975)
A notable exception occurs when the molecule is kept at very low temperature (a few degree °K). See, for example, L. A. Bykovskaya, R.I. Personov and B.M. Kharlamov, Chem.Phys. Letters 27, 80 (1974)
C.A. Sacchi, O. Svelto and G. Prenna, Histochemical Journal 6, 251 (1974)
S. Cova, G. Prenna, C.A. Sacchi, and O. Svelto, in Excited States of Biological Molecules ed. by J.B. Birks, pp.223–232 (Wiley-Interscience, New York, 1975)
A. Albert: The Acridines, 2 nd ed. (Edward Arnold Publishers Ltd, London, 1966) .
Acheson: Acridines (Interscience, New York, 1956)
L.S. Lerman, J.Mol.Biol. 3, 18 (1961)
Ritva-Kaisa Selander, Biochem. J. 131, 749 (1973)
U. Pachman and R. Rigler, Exp. Cell. Res. 72, pp.602–608 (1972)
J.P. Schreiber and M.P. Daune, J.Mol. Biol. 83, 487 (1974)
R.K. Tubbs, W.E. Ditmars, and Q. Van Winkle, J.Mol.Biol. 9, 545 (1964)
Edward J. Modest and Sisir K. Sengupta in “Fluorescence Techniques in Cell Biology” ed. by A.A. Thaer and M. Sernetz (Springer-Verlag Berlin-New York 1973) pp. 125–134
T. Casperson et al. Exp.Cell. Res. 49, 219 (1968)
T. Casperson et al., Chromosorna 30, 215 (1970)
Bernard Weisblum and Pieter L. de Haseth, Proc.Nat.Acad.Sci USA 69, 629 (1972)
J.R. Ellison and H.J. Barr, Chromosoma, 36, 375–390 (1972)
B. Pullman and A. Pullman, Rev. Mod. Phys. 32, 428 (1960)
G. Manolov and Y. Manolova, Nature, Lond. 237, 33 (1972)
W.W. Ware and B.A. Baldwin, J. Chem.Phys. 40, 1703 (1964)
A. Andreoni et al., in Lasers in Physical Chemistry and Biophysics ed. by J. Joussot-Dubien (Elsevier Scientific Publ. Co., Amsterdam, Oxford, New York, 1975) pp. 413–424
A. Andreoni, G. Bottiroli, A. Longoni, C.A. Sacchi, and O. Svelto to be published
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Andreoni, A., Longoni, A., Sacchi, C.A., Svelto, O., Bottiroli, G. (1976). Laser-Induced Fluorescence of Biological Molecules. In: Mooradian, A., Jaeger, T., Stokseth, P. (eds) Tunable Lasers and Applications. Springer Series in Optical Sciences, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-37996-6_26
Download citation
DOI: https://doi.org/10.1007/978-3-540-37996-6_26
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-13481-8
Online ISBN: 978-3-540-37996-6
eBook Packages: Springer Book Archive