Thermally sensitive, hydrophilic, and reactive latex particles as versatile supports for biomolecules immobilization
This article is a short review of recent laboratory work devoted to stimuli-responsive polyalkyl(meth)acrylamide-based hydrophilic colloidal particles and their potential applications in biomedical diagnostics and molecular biology. After a brief introduction and presentation of the main criteria required to design suitable particles for biological purposes, the first part describes shortly several aspects related to synthesizing different types of stimuli-responsive latex particles by radical polymerization of alkyl(meth)acrylamide derivatives. Secondly, the colloidal properties of these colloids are presented. The last part briefly mentions several potential applications of these particles in the biological field.
KeywordsColloidal Particle Microgel Particle Colloidal Property Volume Phase Transition Temperature Biomedical Diagnostics
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