13.6 Concluding Remarks
Calcified non-skeletal matrices and unicellular organisms provide important, reliable models of biological calcification. The following features deserve special consideration:
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The calcified tissues, cells and structures considered in this chapter are analogous with skeletal tissues as far as the presence of organic material in calcified areas is concerned.
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Polysaccharides and proteins are the components most often described in this material; proteolipids and calcium-acidic phospholipid-phosphate complexes do, however, characterize the calcification of oral bacteria.
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Many of these substances are acidic or strongly acidic, and may be phosphorylated.
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Several specific proteins have been isolated and characterized; their descriptive, at least partly subjective names point to the uncertainty of their nature and function.
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Intracellular or extracellular vesicles or compartments have been described as sites of initial calcification.
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(2007). Calcifying Matrices: Non-skeletal Structures. In: Biological Calcification. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36013-1_13
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