Skip to main content
SpringerLink
Log in

The Relationship Between Cell Lineage and Differentiation in the Early Mouse Embryo

  • Chapter
Genetic Mosaics and Cell Differentiation

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 9))

Abstract

The notion that particular types of terminally differentiated cells originate from specific ancestral cells during ontogeny is one of wide currency and long standing. It arose principally from studies on lower chordate and invertebrate embryos carried out in the latter part of the last century and the beginning of the present one (see Davidson, 1976, for a recent review). The concept of stem cells, which may persist into adulthood in a variety of tissues, is clearly related to that of specific cell lineages (Cairnie et al., 1976). Thus neural crest cells, haematocytoblasts, and neuroblasts are believed to give rise to distinct constellations of specific mature cell types.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anderson,D.T.: Embryology and Phylogeny in Annelids and Arthropods. Oxford: Perga-mon Press 1973

    Google Scholar 

  • Anderson, D., Billingham,R. E., Lampkin, G. H., Medawar, P. B.: The use of skin grafting to distinguish between monozygotic and dizygotic twins in cattle. Heredity 5, 379–397 (1961)

    Google Scholar 

  • Anse11,J.D., Snow, M. H. L.: The development of trophoblast in vitro from blastocysts con- taining varying amounts of inner cell mass. J. Embryo ! Exp. Morph. 33, 177–185 (1975)

    Google Scholar 

  • Barlow, P. W., Owen, D., Graham, C. F.: DNA synthesis in the preimplantation mouse em- bryo. J. Embryol. Exp. Morph. 27, 431–445 (1972)

    PubMed  CAS  Google Scholar 

  • Barlow, P. W., Sherman, M.L.: The biochemistry of differentiation of mouse trophoblast: studies on polyploidy. J. Embryo!. Exp. Morph. 27, 44765 (1975)

    Google Scholar 

  • Bellairs,R.: Developmental Processes in Higher Vertebrates. London: Logos Press 1971 Benirschke,K.: Spontaneous chimerism in mammals, a critical review. In: Current Topics in Pathology, Vol. 51, pp. 1–61. Berlin-Heidelberg-New York: Springer 1970

    Google Scholar 

  • Blerkom, J., Van, Barton, S. C., Johnson, M. H.: Molecular differentiation in the preimplantation mouse embryo. Nature (Lond.) 259, 319–321 (1976)

    Google Scholar 

  • Borghese,E., Cassini,A.: Cleavage of mouse egg. In: Rose,G.C. (Ed.): Cinemicrography in Cell Biology, pp. 263–277. New York: Academic Press 1963

    Google Scholar 

  • Brambell,F.W.R.: Ovarian changes. In: Parkes,A.S. (Ed.): Marshall’s Physiology of Reproduction, 3rd Ed., pp. 397–542. London: Longman’s Green 1956

    Google Scholar 

  • Brinster,R.L.: Parental glucose phosphate isomerase activity in three-day mouse embryos. Biochem. Genet. 9, 187–191 (1973)

    Google Scholar 

  • Buehr,M., McLaren,A.: Size regulation in chimaeric mouse embryos. J. Embryol. Exp. Morph. 31, 229–234 (1974)

    Google Scholar 

  • Cairnie, A. B., Lala, P. K., Osmond, D. G. (Eds.): Stem Cells of Renewing Cell Populations. New York: Academic Press 1976

    Google Scholar 

  • Calarco,P.G., Brown, E. H.: An ultrastructural and cytological study of preimplantation development of the mouse. J. Exp. Zool. 171, 253- —284 (1969)

    Google Scholar 

  • Calarco, P. G., Epstein, C. J.: Cell surface changes during preimplantation development in the mouse. Dev. Biol. 32, 208–213 (1973)

    PubMed  CAS  Google Scholar 

  • Cattanach,B.M.: Position effect variegation in the mouse. Genet. Res. 23, 291–306 (1974)

    Google Scholar 

  • Cattanach, B. M., Wolfe, H. G., Lyon, M. F.: A comparative study of the coats of chimaeric mice and those of heterozygotes for X-linked genes. Genet. Res. 19, 213–228 (1972)

    PubMed  CAS  Google Scholar 

  • Chapman, V. M., Adler, D., Labarca,C., Wudl, L.: Genetic variation of ß-glucuronidase ex- pression during early embryogenesis. In: Embryogenesis in Mammals. Ciba Foundation Symposium 29 (new series), pp. 115 124. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • Chapman, V. M., Ansell,J.D., McLaren,A.: Trophoblast giant cell differentiation in the mouse: expression of glucose phosphate isomerase (GP 14)electrophoretic variants in transferred and chimeric embryos. Dev. Biol. 29, 48–54 (1972)

    PubMed  CAS  Google Scholar 

  • Cole,R.J., Paul,J.: Properties of cultured preimplantation mouse and rabbit embryos, and cell strains derived from them. In: Wolstenholme,G.E.W., O’Connor, M. (Eds.): Preimplantation Stages of Pregnancy. Ciba Foundation Symposium, pp. 82 112. London: Churchill 1965

    Google Scholar 

  • Conklin, E.G.: The organisation and cell-lineage of the ascidian egg. J. Acad. Natl. Sci. Philad. 13, 5–119 (1905)

    Google Scholar 

  • Crick, F. H. C., Lawrence, P.A.: Compartments and polyclones in insect development. Science 189, 340 347 (1975)

    Google Scholar 

  • Dalcq,A.M.: Introduction to General Embryology. London: Oxford University Press 1957

    Google Scholar 

  • Daniel, J. C., Jr.: Methods in Mammalian Embryology. San Francisco: Freeman 1971

    Google Scholar 

  • Daniel,J. C., Jr.: Methods in Mammalian Reproduction. New York: Academic Press 1978

    Google Scholar 

  • Davidson, E. H.: Gene Activity in Early Development, 2nd ed. New York: Academic Press 1976

    Google Scholar 

  • Denker,H.-W.: Formation of the blastocyst: determination of trophoblast and embryonic knot. In: Gropp,A. (Ed.): Current Topics in Pathology, Vol. 62, pp. 59–79. BerlinHeidelberg-New York: Springer 1976

    Google Scholar 

  • Deol, M. S.: Spotting genes and internal pigmentation patterns in the mouse. J. Embryol. Exp. Morph. 26, 123 —133 (1971)

    Google Scholar 

  • Deol, M.S.: The role of the tissue environment in the expression of spotting genes in the mouse. J. Embryol. Exp. Morph. 30, 483–489 (1973)

    PubMed  CAS  Google Scholar 

  • Deol, M. S., Whitten, W. K.: Time of X-chromosome inactivation in retinal melanocytes of the mouse. Nature (New Biol.) 238 159–160 (1972 a)

    Google Scholar 

  • Deol, M. S., Whitten, W. K.: X-chromosome inactivation: does it occur at the same time in all cells of the embryo? Nature (New Biol.) 240 277–279 (1972 b)

    Google Scholar 

  • Dickson, A. D.: The form of the mouse blastocyst. J. Anat. 100, 335–348 (1966)

    PubMed  CAS  Google Scholar 

  • Dienstman,S.R., Holtzer,H.: Myogenesis: a cell lineage interpretation. In: Reinert,J., Holt- zer,H. (Eds.): Results and Problems in Cell Differentiation, Vol. VII: Cycle and Cell Differentiation, pp. 1–25. Berlin-Heidelberg-New York: Springer 1975

    Google Scholar 

  • Diwan, S. B., Stevens, L. C.: Development of teratomas from the ectoderm of mouse egg cylinders. J. Natl. Cancer Inst. 57, 937–939 (1976)

    PubMed  CAS  Google Scholar 

  • Dulcibella, T., Albertini, D. F., Anderson, E., Biggers, J. D.: The preimplantation mammalian embryo: characterisation of intercellular junctions and their appearance during development. Dev. Biol. 45, 231–250 (1975)

    Google Scholar 

  • Dulcibella, T., Anderson, E.: Cell shape and membrane changes in the eight-cell mouse em- bryo: prerequisites for morphogenesis of the blastocyst. Dev. Biol. 47, 45–58 (1975)

    Google Scholar 

  • Eager, D. D., Johnson, M. H., Thurley, K. W.: Ultrastructural studies on the surface membrane of the mouse egg. J. Cell Sci. 22, 345–353 (1976)

    PubMed  CAS  Google Scholar 

  • Enders,A.C.: The fine structure of the blastocyst. In: Blandau,R.J. (Ed.): Biology of the Blastocyst, pp. 71 94. Chicago: Univ. of Chicago Press 1971

    Google Scholar 

  • Fialkow,P.J.: Primordial cell pool size and lineage relationships of five human cell types. Ann. Hum. Genet. (Lond.) 37, 39–48 (1973)

    Google Scholar 

  • Ford, C. E.: Mosaics and chimaeras. Br. Med. Bull. 25, 104–109 (1969)

    PubMed  CAS  Google Scholar 

  • Ford, C. E., Evans, E. P., Burtenshaw, M. D., Clegg, H., Barnes, R. D., Tuffrey, M.: Marker chromosome analysis of tetraparental AKR—CBA-T6 mouse chimaeras. Differentiation 2, 321–333 (1974)

    PubMed  CAS  Google Scholar 

  • Ford, C. E., Evans, E. P., Gardner, R. L.: Marker chromosome analysis of two mouse chimaeras. J. Embryol. Exp. Morph. 33, 447–457 (1975)

    PubMed  CAS  Google Scholar 

  • Fraser, A. S., Short, B. F.: Studies of sheep mosaic for fleece type I. Patterns and origins of mosaicism. Aust. J. Biol. Sci. 11, 200–208 (1958)

    Google Scholar 

  • Gandini, E., Gartler, S. M., Angioni,G., Argiolas,N., D ell’Acqua, G.: Developmental implications of multiple tissue studies in glucose-6-phosphate dehydrogenase-deficient heterozygotes. Proc. Natl. Acad. Sci. USA 61, 945–948 (1968)

    CAS  Google Scholar 

  • Gardner,R. L.: Mouse chimaeras obtained by the injection of cells into the blastocyst. Nature (Lond.) 220, 596–597 (1968)

    Google Scholar 

  • Gardner, R. L.: Manipulations on the blastocyst. Adv. Biosci. 6, 279— 296 (1971)

    Google Scholar 

  • Gardner, R. L.: Microsurgical approaches to the study of early mammalian development. In: Moghissi,K.S. (Ed.): Birth Defects and Fetal Development: Endocrine and Metabolic Factors, pp. 212–233. Illinois: Thomas 1974

    Google Scholar 

  • Gardner, R. L.: Origin and properties of trophoblast. In: Edwards, R. G., H owe, C. W. S., Johnson,M.H. (Eds.): Immunobiology of Trophoblast, pp. 43— 65. London: Cambridge Univ. Press 1975a

    Google Scholar 

  • Gardner, R. L.: Analysis of determination and differentiation in the early mammalian embryo using intra-and inter-specific chimaeras. In: Markert,C. L. (Ed.): The Developmental Biology of Reproduction. 33rd Symposium of The Society for Developmental Biology, pp. 207–238. New York: Academic Press 19756

    Google Scholar 

  • Gardner, R. L.: The problem of intrauterine orientation of the implanting mouse blastocyst. J. Anat. (Lond.) 124, 236 (1977)

    Google Scholar 

  • Gardner,R.L.: Production of chimeras by injecting cells or tissue into the blastocyst. In: Daniel,J.C., Jr. (Ed.): Methods in Mammalian Reproduction. New York: Academic Press 1978

    Google Scholar 

  • Gardner, R. L., Johnson, M. H.: An investigation of inner cell mass and trophoblast tissues following their isolation from the mouse blastocyst. J. Embryol. Exp. Morph. 28, 279 312 (1972)

    Google Scholar 

  • Gardner, R. L., Johnson,M. H.: Investigation of early mammalian development using inter-specific chimaeras between rat and mouse. Nature (New Biol.) 246, 86 —89 (1973)

    Google Scholar 

  • Gardner, R. L., Johnson,M.H.: Investigation of cellular interaction and deployment in the early mammalian embryo using inter-specific chimaeras between rat and mouse. In: Cell Patterning. Ciba Foundation Symposium 29 (new series), pp. 183–200. Amsterdam: Elsevier, Excerpta Medica 1975

    Google Scholar 

  • Gardner,R.L., Lyon,M.F.: X-chromosome inactivation studied by injection of a single cell into the mouse blastocyst. Nature (Lond.) 231, 385- -386 (1971)

    Google Scholar 

  • Gardner, R. L., Papaioannou, V. E.: Differentiation in the trophectoderm and inner cell mass. In: Balls, M., Wild,A.E. (Eds.): The Early Development of Mammals. 2nd Symposium of The British Society for Developmental Biology, pp. 107–132. London: Cambridge Univ. Press 1975

    Google Scholar 

  • Gardner, R. L., Rossant,J.: Determination during embryogenesis. In: Embryogenesis in Mammals. Ciba Foundation Symposium 40 (new series), pp. 5 18. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • Gardner, R. L., Rossant, J.: The potency of primitive endoderm and primitive ectoderm cells isolated from 4’/2 day p.c. mouse blastocysts. (in preparation) (1977)

    Google Scholar 

  • Gardner, R.L., Papaioannou, V. E., Barton, S.C.: Origin of the ectoplacental cone and secondary giant cells in mouse blastocysts reconstituted from isolated trophoblast and inner cell mass. J. Embryol. Exp. Morph. 30, 561–572 (1973)

    PubMed  CAS  Google Scholar 

  • Garner, W., McLaren,A.: Cell distribution in chimaeric mouse embryos before implantation. J. Embryol. Exp. Morph. 32, 495–503 (1974)

    PubMed  CAS  Google Scholar 

  • Gearhart,J.D., Mintz,B.: Glucosephosphate isomerase subunit-reassociation tests for maternal-fetal and fetal-fetal cell fusion in the mouse placenta. Dev. Biol. 29, 55–64 (1972)

    Google Scholar 

  • Gehring,W.J.: The stability of the determined state in cultures of imaginal disks in Drosophila. In: Ursprung, FL, Nöthiger, R. (Eds.): Results and Problems in Cell Differentiation, Vol. V: The Biology of Imaginal Disks, pp. 35— 58. Berlin-Heidelberg-New York: Springer 1972

    Google Scholar 

  • Green,M.C.: Mutant genes and linkages. In: Green,E.L. (Ed.): Biology of the Laboratory Mouse, 2nd ed, pp. 87–150. New York: McGraw-Hill 1966

    Google Scholar 

  • Gruneberg,H.: The case for somatic crossing over in the mouse. Genet. Res. 7 58–75 (1966 a) Gruneberg,H.: More about the tabby mouse and about the Lyon hypothesis. J. Embryol. Exp. Morph. 16 569–590 (1966 b)

    Google Scholar 

  • Gruneberg,H., McLaren, A.: The skeletal phenotype of some mouse chimaeras. Proc. R. Soc. Lond. B., 182, 183–192 (1972)

    Google Scholar 

  • Gulyas,B.J.: A reexamination of cleavage patterns in eutherian mammalian eggs: rotation of blastomere pairs during second cleavage in the rabbit. J. Exp. Zool. 193, 235–248 (1975)

    Google Scholar 

  • Hamilton, W. J., Mossman,H. W.: Hamilton, Boyd and Mossman’s Human Embryology, 4th ed. Cambridge: Helfer 1972

    Google Scholar 

  • Handyside,A.H., Johnson,M.H.: Control mechanisms in the differentiation of the mouse blastocyst. Il. The timing of determination and differentiation. J. Anat. (Lond.) 124, 236 (1977)

    Google Scholar 

  • Herbert, M. C., Graham, C. F.: Cell determination and biochemical differentiation of the early mammalian embryo. In: Current Topics in Developmental Biology, Vol. VIII, pp. 152 178. New York: Academic Press 1974

    Google Scholar 

  • Hillman, N., Sherman, M.1., Graham, C. F.: The effect of spatial arrangement on cell determi- nation during mouse development. J. Embryol. Exp. Morph. 28, 261–278 (1972)

    Google Scholar 

  • Hogan, B., Tilly,R.: In vitro culture and differentiation of normal mouse blastocysts. Nature (Lond.) 265, 626–629 (1977)

    CAS  Google Scholar 

  • Holtzer, H., Rubinstein,N., Fellini, S., Yeoh,G., Chi,J., Birnbaum,J., Okayama, M.: Lineage, quantal cell cycles, and the generation of diversity. Quart. Rev. Biophys. 8, 523–557 (1975)

    CAS  Google Scholar 

  • Horstadius,S.: Experimental Embryology of Echinoderms. Oxford: Clarendon Press 1973 Hutchison, H. T.: A model for estimating the extent of variegation in mosaic tissues. J. Theor. Biol. 38, 61 79 (1973)

    Google Scholar 

  • Illmensee,K., Mintz,B.: Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts. Proc. Natl. Acad. Sci. USA 73, 549–553 (1976)

    Google Scholar 

  • Izquierdo,L., Ortiz,M.E.: Differentiation in the mouse morulae. Wilhelm Roux ’ Arch. 177, 67–74 (1975)

    Google Scholar 

  • Johnson, M. H., Eager, D., Muggleton-Harris,A., Grave, H. M.: Mosaicism in organisation of concanavalin A receptors on surface membrane of mouse eggs. Nature (Lond.) 257, 321–322 (1975)

    CAS  Google Scholar 

  • Johnson,M. H., Gardner,R. L.: Analysis of rat: mouse chimaeras by immunofluorescence; a preliminary report. In: Centaro,A., Caretti,N. (Eds.): Immunology in Obstetrics and Gynaecology. Proc. 1st Int. Cong. Immunology of Obstetrics and Gynaecology, Padua, 1973, pp. 312 314. Amsterdam: Elsevier, Excerpta Medica 1975

    Google Scholar 

  • Kelly,S.J.: Studies of the potency of the early cleavage blastomeres of the mouse. In: Balls, M., Wild, A. E. (Eds.): The Early Development of Mammals. 2nd Symposium of The British Society for Developmental Biology, pp. 97–105. Cambridge: Cambridge Univ. Press 1975

    Google Scholar 

  • Kirby, D. R.S., Potts, D. M., Wilson, I. B.: On the orientation of the implanting blastocyst. J. Embryol. Exp. Morph. 17, 527–532 (1967)

    PubMed  CAS  Google Scholar 

  • Lawrence, P.A.: The cell cycle and cellular differentiation in insects. In: Reinert, J., Holtzer,H. (Eds.): Results and Problems in Cell Differentiation, Vol. VII: Cell Cycle and Cell Differentiation, pp. I II —121. Berlin-Heidelberg-New York: Springer 1975

    Google Scholar 

  • Le Douarin,N.: Cell migration in early vertebrate development studied in inter-specific chimaeras. Embryogenesis in Mammals. Ciba Foundation Symposium 40 (new series), pp. 71 97. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • Lewis,J.: The theory of clonal mixing during growth. J. Theor. Biol. 39, 47–54 (1973)

    Google Scholar 

  • Lewis,J.H., Summerbell,D., Wolpert,L.: Chimaeras and cell lineage in development. Nature (Lond.) 239, 276— 278 (1972)

    Google Scholar 

  • Lin,T.P.: Microsurgery of inner cell mass of mouse blastocysts. Nature (Lond.) 222, 480–481 (1969)

    Google Scholar 

  • Lyon,M.F.: Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (Lond.) 190, 372–373 (1961)

    Google Scholar 

  • Lyon,M.F.: Mechanisms and evolutionary origins of variable X-chromosome activity in mammals. Proc. R. Soc. Lond. B. 187, 243–268 (1974)

    Google Scholar 

  • Martin,G., Evans, M. H.: Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc. Natl. Acad. Sci. USA 72, 1441–1445 (1975)

    Google Scholar 

  • Mayer,T.C.: A comparison of pigment cell development in albino, steel, and dominant-spotting mutant mouse embryos. Dev. Biol. 23, 297–309 (1970)

    Google Scholar 

  • Mayer,T.C., Fishbane,J.L.: Mesoderm-ectoderm interactions in the production of agouti pigmentation pattern in mice. Genetics 71, 297–303 (1972)

    Google Scholar 

  • McLarcn,A.: Numerology of development. Nature (Lond.) 239, 274–276 (1972)

    Google Scholar 

  • McLaren,A.: Mammalian Chimaeras. Cambridge: Cambridge University Press 1976a McLaren,A.: Growth from fertilisation to birth in the mouse. In: Embryogenesis in Mam- mals. Ciba Foundation Symposium 40 (new series), pp. 47 51. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • McLaren,A., Bowman, P.: Mouse chimaeras derived from fusion of embryos differing by nine genetic factors. Nature (Lond.) 224, 236–240 (1969)

    Google Scholar 

  • McLaren,A., Hensleigh,H.C.: Culture of mammalian embryos over the implantation period. In: Balls,M., Wild,A. E. (Eds.): The Early Development of Mammals. 2nd Symposium of the British Society for Developmental Biology, pp. 45–60. Cambridge: Cambridge University Press 1975

    Google Scholar 

  • Melvold, R. W.: Spontaneous somatic reversion in mice. Effects of parental genotype on stability at the p-locus. Mutat. Res. 12, 171–174 (1971)

    PubMed  CAS  Google Scholar 

  • Metcalf, D., Moore, M. A. S.: Haemopoietic Cells. Amsterdam: North-Holland 1971

    Google Scholar 

  • Mintz,B.: Formation of genotypically mosaic mouse embryos. Am. Zool. 2, 432 (Abstr. 310 ) (1962)

    Google Scholar 

  • Mintz,B.: Formation of genotypically mosaic mouse embryos and early development of “lethal (t12/t’2)-Normal” mosaics. J. Exp. Zool. 157, 273–292 (1964)

    Google Scholar 

  • Mintz, B.: Experimental genetic mosaicism in the mouse. In: Wolstenholme, G. E. W., O’Connor,M. (Eds.): Preimplantation Stages of Pregnancy. Ciba Foundation Symposium, pp. 194–207. London: Churchill 1965

    Google Scholar 

  • Mintz,B.: Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes. Proc. Natl. Acad. Sci. USA 58, 344–351 (1967)

    Google Scholar 

  • Mintz,B.: Gene expression in allophenic mice. In: Padykula, H.A. (Ed.): Control Mechanisms in the Expression of Cellular Phenotypes, pp. 15- -42. New York: Academic Press 1970

    Google Scholar 

  • Mintz,B.: Clonal basis of mammalian differentiation. In: Davies, D. D., Balls, M. (Eds.): Con- trol Mechanisms of Growth and Differentiation. Symposia of the Society for Experimen- tal Biology XXV, pp. 345–370. Cambridge: Cambridge University Press 1971

    Google Scholar 

  • Mintz,B.: Clonal differentiation in early mammalian development. In: Sussman, M. (Ed.): Molecular Genetics and Developmental Biology, pp. 455- -474. New Jersey: Prentice-Hall 1972a

    Google Scholar 

  • Mintz,B.: Clonal units of gene control in mammalian differentiation. In: Harris,R., Allin,P., Viza,D. (Eds.): Cell Differentiation, pp. 267–271. Copenhagen: Munksgaard 1972b

    Google Scholar 

  • Mintz, B.: Gene control of mammalian differentiation. Ann. Rev. Genet. 8, 411–470 (1974)

    PubMed  CAS  Google Scholar 

  • Mintz, B., Illmensee, K.: Normal genetically mosaic mice produced from malignant teratocar- cinoma cells. Proc. Natl. Acad. Sci. USA 72, 3585–3589 (1975)

    PubMed  CAS  Google Scholar 

  • Mintz,B., Illmensee,K., Gearhart,J.D.: Developmental and experimental potentialities of mouse teratocarcinoma cells from embryoid body cores. In: Sherman, M. I., Solter,D. (Eds.): Teratomas and Differentiation, pp. 59 82. New York: Academic Press 1975

    Google Scholar 

  • Mintz,B., Palm,J.: Gene control of hematopoiesis. I. Erythrocyte mosaicism and permanent immunological tolerance in allophenic mice. J. Exp. Med. 129, 1013–1027 (1969)

    Google Scholar 

  • Mintz, B., Sanyal, S.: Clonal origin of the mouse visual retina mapped from genetically mosaic eyes. Genetics 64, (suppl.), 43–44 (1970)

    Google Scholar 

  • Mintz,B., Silvers, W. K.: Histocompatibility antigens on melanoblasts and hair follicle cells. Transplantation 9, 497–505 (1970)

    Google Scholar 

  • Morata,G., Lawrence, P. A.: Control of compartment development by the engrailed gene in Drosophila. Nature (Lond.) 255, 614–617 (1975)

    CAS  Google Scholar 

  • Mulnard,J.G.: Studies of regulation of mouse ova in vitro. In: Wolstenholme,G.E.W., O’Connor, M. (Eds.): Preimplantation Stages of Pregnancy. Ciba Foundation Symposium, pp. 123 138. London: Churchill 1965

    Google Scholar 

  • Mulnard,J.G.: Analyse microcinématographique du développement de l’oeuf de souris du stade II au blastocyste. Arch. Biol. (Liege) 78, 107–138 (1967)

    CAS  Google Scholar 

  • Mystkowska, E. T.: Development of mouse-bank vole interspecific chimaeric embryos. J. Embryol. Exp. Morph. 33, 731–744 (1975)

    PubMed  CAS  Google Scholar 

  • Nadijcka,M., Hillman,N.: Ultrastructural studies of mouse blastocyst substages. J. Embryol. Exp. Morph. 32, 675–695 (1974)

    Google Scholar 

  • Nesbitt,M.N.: X-chromosome inactivation mosaicism in the mouse. Dev. Biol. 26, 252–263 (1971)

    Google Scholar 

  • Nesbitt,M.N.: Chimaeras vs. X inactivation mosaics: significance of differences in pigment distribution. Dev. Biol. 38, 202–207 (1974)

    Google Scholar 

  • Nesbitt, M. N., Gartler, S. M.: The application of genetic mosaicism to developmental problems. Ann. Rev. Genet. 5, 143–162 (1971)

    PubMed  CAS  Google Scholar 

  • Nicolet,G.: La chronologie d’invagination chez le poulet: etude à l’aide de la thymidine tritiée. Experientia 23, 576–577 (1967)

    Google Scholar 

  • Nöthiger,R.: The larval development of imaginal disks. In: Ursprung, H., Nöthiger, R. (Eds.): Results and Problems in Cell Differentiation, Vol. V: The Biology of Imaginal Disks, pp. t 34. Berlin-Heidelberg-New York: Springer 1972

    Google Scholar 

  • Nowell, P. C., H irsch, B. E., Fox, D. H., Wilson, D. B.: Evidence for the existence of multipoten- tial lymphohaemopoietic stem cells in the adult rat. J. Cell. Physiol. 75, 151–158 (1970)

    PubMed  CAS  Google Scholar 

  • Ozdzenski, W.: Observations on the origin of primordial germ cells in the mouse. Zool. Pol. 17, 367–379 (1967)

    Google Scholar 

  • Papaioannou, V. E., McBurney, M. W., Gardner, R. L., Evans, M. H.: Fate of teratocarcinoma cells injected into early mouse embryos. Nature (Lond.) 258, 70–73 (1975)

    CAS  Google Scholar 

  • Pinsker, M. C., Mintz, B.: Change in cell surface glycoproteins of mouse embryos before implantation. Proc. Natl. Acad. Sci. USA 70, 1645–1648 (1973)

    PubMed  CAS  Google Scholar 

  • Poole,T. W.: Dermal-epidermal interactions and the site of action of the yellow (A)’) and nonagouti (a) coat colour genes in the mouse. Dev. Biol. 36, 208–211 (1974)

    Google Scholar 

  • Raven, Chr. P.: Oogenesis. Oxford: Pergamon Press 1961

    Google Scholar 

  • Rawles, M. E.: Origin of pigment cells from the neural crest in the mouse embryo. Physiol. Zool. 20, 248–266 (1947)

    PubMed  CAS  Google Scholar 

  • Reverberi,G.: Experimental Embryology of Marine and Fresh-water Invertebrates. Amsterdam: North-Holland 1971

    Google Scholar 

  • Rossant, J.: Investigation of the determinative state of the mouse inner cell mass. I. Aggregation of isolated inner cell masses with morulae. J. Embryol. Exp. Morph. 33 979–990 (1975 a)

    Google Scholar 

  • Rossant, J.: Investigation of the determinative state of the mouse inner cell mass. Il. The fate of isolated inner cell masses transferred to the oviduct. J. Embryol. Exp. Morph. 33 9911001 (1975 b)

    Google Scholar 

  • Rossant, J.: Investigation of inner cell mass determination by aggregation of isolated rat inner cell masses with mouse morulae. J. Embryol. Exp. Morph. 36, 163–174 (1976)

    PubMed  CAS  Google Scholar 

  • Rossant, J.: Cell commitment in early rodent development. In: Johnson, M. H. (Ed.): Develop- ment in Mammals, Vol. II, pp. 119–150. Amsterdam: Elsevier, North-Holland 1977

    Google Scholar 

  • Rossant,J., Ofer,L.: Properties of extraembryonic ectoderm isolated from postimplantation mouse embryos. J. Embryol. Exp. Morph. (in press) (1977)

    Google Scholar 

  • Rossant, J., Papaioannou, V. E.: The Biology of embryogenesis. In: Sherman, M. I. (Ed.): Con- cepts in Mammalian Embryogenesis, pp. 1–36. Cambridge/Mass.: MIT Press 1977

    Google Scholar 

  • Rowinski,J., Solter,D., Koprowski,H.: Change of concanavalin A induced agglutinability during preimplantation mouse development. Exp. Cell Res. 100, 404–408 (1976) Rugh,R.: The Mouse: Its Reproduction and Development. Minneapolis: Burgess 1968

    Google Scholar 

  • Russell, L. B.: Genetic and functional mosaicism in the mouse. In: Locke, M. (Ed.): The Role of Chromosomes in Development. 23rd Symposium of the Society for the Study of Development and Growth, pp. 153–181. New York: Academic Press 1964

    Google Scholar 

  • Russell, L. B., Major, M. H.: Radiation-induced presumed somatic mutations in the house mouse. Genetics 42, 161–175 (1957)

    PubMed  CAS  Google Scholar 

  • Schaible,R. H.: Clonal distribution of melanocytes in piebald-spotted and variegated mice. J. Exp. Zool. 172, 181 200 (1969)

    Google Scholar 

  • Searle,A.G.: Comparative Genetics of Coat Colour in Mammals. London: Logos Press 1968 Sengel, P.: Morphogenesis of Skin. Cambridge: Cambridge Univ. Press 1976

    Google Scholar 

  • Sherman,M.I.: The role of cell-cell interactions during early mouse embryogenesis. In: Balls, M., Wild, A. E. (Eds.): The Early Development of Mammals: 2nd Symposium of The British Society for Developmental Biology, pp. 145–165. Cambridge: Cambridge University Press 1975

    Google Scholar 

  • Sherman,M.I., McLaren,A., Walker, P. M. B.: Mechanism of accumulation of DNA in giant cells of mouse trophoblast. Nature (New Biol.) 238, 175–176 (1972)

    Google Scholar 

  • Silvers, W. K., Russell, E. S.: An experimental approach to action of genes at the agouti locus in the mouse. J. Exp. Zool. 130, 199–220 (1955)

    Google Scholar 

  • Skreb,N., Svajger,A., Levak-Svajger,B.: Developmental potentialities of the germ layers in mammals. In: Embryogenesis in Mammals. Ciba Foundation Symposium 40 (new series), pp. 27 39. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • Snell, G. D., Stevens,L. C.: Early embryology. In: Green, E. L. (Ed.): Biology of the Laboratory Mouse, pp. 205–245. New York: McGraw-Hill 1966

    Google Scholar 

  • Snow,M. H. L.: The differential effect of [3H]-thymidine upon two populations of cells in pre-implantation mouse embryos. In: Balls, M., Billett, F. S. (Eds.): The Cell Cycle in Development and Differentiation. 1st Symposium of The British Society for Developmental Biology, pp. 311 324. London: Cambridge University Press 1973a

    Google Scholar 

  • Snow,M. H. L.: Abnormal development of pre-implantation mouse embryos grown in vitro with [3H]-thymidine. J. Embryol. Exp. Morph. 29 601–615 (1973 b)

    Google Scholar 

  • Snow, M. H. L.: Embryo growth during the immediate postimplantation period. In: Embryogenesis in Mammals. Ciba Foundation Symposium 40 (new series), pp. 53- -66. Amsterdam: Elsevier, Excerpta Medica 1976

    Google Scholar 

  • Snow, M. H. L., Ansell,J.D.: The chromosomes of giant trophoblast cells of the mouse. Proc. R. Soc. (Lond.) B. 187, 93–98 (1974)

    CAS  Google Scholar 

  • Solter,D., Knowles,B.B.: Immunosurgery of mouse blastocysts. Proc. Natl. Acad. Sci. USA 72, 5099 5102 (1976)

    Google Scholar 

  • Staats,J.: Standardized nomenclature for inbred strains of mice: fifth listing. Cancer Res. 32, 1609 1646 (1972)

    Google Scholar 

  • Stern, M. S.: Experimental studies on the organisation of the early rodent embryo. II. Reaggregation of disaggregated embryos. J. Embryol. Exp. Morph. 28, 255–261 (1972)

    PubMed  CAS  Google Scholar 

  • Stern, M. S., Wilson, I. B.: Experimental studies on the organisation of the preimplantation mouse embryo. I. Fusion of asynchronously cleaving eggs. J. Embryol. Exp. Morph. 28, 247–254 (1972)

    CAS  Google Scholar 

  • Strickland, S., Reich, E., Sherman, M. I.: Plasminogen activator in early embryogenesis: en-zyme production by trophoblast and parietal endoderm. Cell 9, 231–240 (1976)

    PubMed  CAS  Google Scholar 

  • Tarkowski, A. K.: Mouse chimaeras developed from fused eggs. Nature (Lond.) 190, 857–860 (1961)

    CAS  Google Scholar 

  • Tarkowski,A.K., Wroblewska,J.: Development of blastomeres of mouse eggs isolated at the four-and eight-cell stage. J. Embryol. Exp. Morph. 18, 155–180 (1967)

    Google Scholar 

  • Tettenborn,U., Dofuku,R., Ohno,S.: Noninducible phenotype exhibited by a proportion of female mice heterozygous for X-linked testicular feminization mutation. Nature (Lond.) 234, 37–40 (1971)

    Google Scholar 

  • Theiler, K.: The House Mouse. Berlin-Heidelberg-New York: Springer 1972

    Google Scholar 

  • Vogt,W.: Gestaltungsanalyse am Amphibienkeim mit örtlicher Vitalfärbung. II. Teil: Gastrulation and Mesodermbildung bei Urodelen and Anuren. Wilhelm Roux ’ Arch. 120, 385–706 (1929)

    Google Scholar 

  • Wassarman,P.M., Albertini, D. F., Josefowicz,W.J., Letourneau,G.E.: Cytochalasin B-induced pseudo-cleavage of mouse oocytes in vitro: asymmetric localization of mitochondria and microvilli associated with a stage-specific response. J. Cell Sci. 21, 523–535 (1976)

    Google Scholar 

  • Wegmann,T.G., Gilman,J.G.: Chimerism for three genetic systems in tetraparental mice. Dev. Biol. 21, 281–291 (1970)

    Google Scholar 

  • West,J.D.: A theoretical approach to the relation between patch size and clone size in chimaeric tissues. J. Theor. Biol. 50, 153 160 (1975)

    Google Scholar 

  • West, J. D.: Clonal development of the retinal epithelium in mouse chimaeras and X-inactivation mosaics. J. Embryol. Exp. Morph. 35 445–461 (1976 a)

    Google Scholar 

  • West,J. D.: Distortion of patches of retinal degeneration in chimaeric mice. J. Embryo!. Exp. Morph. 36 145 149 (1976 b)

    Google Scholar 

  • West,J.D., McLaren,A.: The distribution of melanocytes in the dorsal coats of a series of chimaeric mice. J. Embryol. Exp. Morph. 35, 87–93 (1976)

    Google Scholar 

  • Weston,J.A.: Cell marking. In: Wilt,F.H., Wessells, N. K. (Eds.): Methods in Developmental Biology, pp. 723— 736. New York: Crowell 1967

    Google Scholar 

  • Whang,J., Frei, E., Tjio,J.H., Carbone, P.P., Brecher,G.: The distribution of the Philadelphia chromosome in patients with chronic myelogenous leukaemia. Blood 22, 664–673 (1963)

    Google Scholar 

  • Wilson,I.B., Bolton,E., Cuttler,R.H.: Preimplantation differentiation in the mouse egg as revealed by microinjection of vital markers. J. Embryol. Exp. Morph. 27, 467–479 (1972)

    Google Scholar 

  • Wilson, LB., Stern, M. S.: Organisation in the preimplantation embryo. In: Balls, M.,Wild,A.E. (Eds.): The Early Development of Mammals. 2nd Symposium of The British Society for Developmental Biology, pp. 81 95. Cambridge: Cambridge University Press 1975

    Google Scholar 

  • Wolfe, H. G., Coleman, D. L.: Pigmentation. In: Green, E. L. (Ed.): Biology of the Laboratory Mouse, pp. 405–425. New York: McGraw-Hill 1966

    Google Scholar 

  • Wolpert,L., Gingell,D.: Striping and the pattern of melanocyte cells in chimaeric mice. J. Theor. Biol. 29, 147–150 (1970)

    PubMed  CAS  Google Scholar 

  • Wu,A. M., Till, J. E., Siminovitch, L., McCulloch, E.A.: Cytological evidence for a relationship between normal haemopoietic colony-forming cells and cells of the lymphoid system. J. Exp. Med. 127, 455–464 (1968)

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Zoology, University of Oxford, Oxford, Great Britain

    Richard L. Gardner

Authors
  1. Richard L. Gardner
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung Zellbiologie, Biozentrum der Universität, Klingelbergstraße 70, CH-4056, Basel, Switzerland

    W. J. Gehring

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Gardner, R.L. (1978). The Relationship Between Cell Lineage and Differentiation in the Early Mouse Embryo. In: Gehring, W.J. (eds) Genetic Mosaics and Cell Differentiation. Results and Problems in Cell Differentiation, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35803-9_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-35803-9_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21952-2

  • Online ISBN: 978-3-540-35803-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation