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Results in Liver Metastatic Colorectal Cancer

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Liver Radioembolization with 90Y Microspheres

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Patients with metastatic colorectal cancer (mCRC) involving the liver present several therapeutic challenges for the oncology team. The majority of patients will not be candidates for potentially curative surgical resection and therefore must rely on other local therapies to augment systemic cheotherapy. Unlike some other solid tumors with liver métastases, mCRC patients now have access to a plethora of new biologic agents and cytotoxic drugs that did not exist a decade ago. Changes in liver arterial caliber and tolerance of liver lobules to radiation are both negatively effected by these new systemic therapies and have had an impact on aspects of microsphere therapy.

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Authors and Affiliations

  1. Wake Radiology Oncology, PLLC, 300 Ashville Avenue, Suite 110, Cary, NC, 27511, USA

    Andrew S. Kennedy MD, FACRO (Co-Medical Director)

  2. Wake Radiology Oncology, PLLC, 300 Ashville Avenue, Suite 110, Cary, NC, 27511, USA

    William A. Dezarn PhD, DABR (Chief of Medical Physics)

  3. School of Medicine, University of North Carolina, Chapel Hill, Chapel Hill, NC, 27599, USA

    Patrick McNeillie BS, MSI

Authors
  1. Andrew S. Kennedy MD, FACRO
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  2. William A. Dezarn PhD, DABR
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  3. Patrick McNeillie BS, MSI
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Editors and Affiliations

  1. Department of Radiology Clínica Universitaria, Universidad de Navarra, Avenida de Pio XII, 36, 31008, Pamplona, Spain

    José I. Bilbao PhD (Professor) (Professor)

  2. Department of Clinical Radiology, University Hospitals - Grosshadern and Innenstadt Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377, Munich, Germany

    Maximilian F. Reiser MD (Professor and Chairman) (Professor and Chairman)

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Kennedy, A.S., Dezarn, W.A., McNeillie, P. (2008). Results in Liver Metastatic Colorectal Cancer. In: Bilbao, J.I., Reiser, M.F. (eds) Liver Radioembolization with 90Y Microspheres. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35423-9_11

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  • DOI: https://doi.org/10.1007/978-3-540-35423-9_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-35421-5

  • Online ISBN: 978-3-540-35423-9

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