Abstract
The first publication about a confocal fluorescence microscope integrated into the distal tip of a conventional colonoscope (Pentax EC 3830FK, Tokyo, Japan) appeared in 2004 [1], showing that in vivo microscopy at subcellular resolution (0.7 µm) simultaneously displayed with white-light endoscopy had become possible. Today, endomicroscopy can be performed in the upper and lower GI tract [2]–[10]. This chapter deals with the examination technique of confocal laser endomicroscopy.
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References
Kiesslich R, Burg J, Vieth M et al (2004) Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo. Gastroenterology 127:706–713
Thong PS, Olivo M, Kho KW, Zheng W, Mancer K, Harris M, Soo KC (2007) Laser confocal endomicroscopy as a novel technique for fluorescence diagnostic imaging of the oral cavity. J Biomed Opt 12:014007
Hoffman A, Goetz M, Vieth M, Galle PR, Neurath MF, Kiesslich R (2006) Confocal laser endomicroscopy: technical status and current indications. Endoscopy 38:1275–1283
Kitabatake S, Niwa Y, Miyahara R, Ohashi A, Matsuura T, Iguchi Y, Shimoyama Y, Nagasaka T, Maeda O, Ando T, Ohmiya N, Itoh A, Hirooka Y, Goto H (2006) Confocal endomicroscopy for the diagnosis of gastric cancer in vivo. Endoscopy 38:1110–1114
Kakeji Y, Yamaguchi S, Yoshida D, Tanoue K, Ueda M, Masunari A, Utsunomiya T, Imamura M, Honda H, Maehara Y, Hashizume M (2006) Development and assessment of morphologic criteria for diagnosing gastric cancer using confocal endomicroscopy: an ex vivo and in vivo study. Endoscopy 38:886–890
Hurlstone DP, Sanders DS (2006) Recent advances in chromoscopic colonoscopy and endomicroscopy. Curr Gastroenterol Rep 8:409–415
Goetz M, Hoffman A, Galle PR, Neurath MF, Kiesslich R (2006) Confocal laser endoscopy: new approach to the early diagnosis of tumors of the esophagus and stomach. Future Oncol 2:469–476
Kiesslich R, Gossner L, Goetz M, Dahlmann A, Vieth M, Stolte M, Hoffman A, Jung M, Nafe B, Galle PR, Neurath MF (2006) In vivo histology of Barrett’s esophagus and associated neoplasia by confocal laser endomicroscopy. Clin Gastroenterol Hepatol 4:979–987
Kiesslich R, Hoffman A, Goetz M, Biesterfeld S, Vieth M, Galle PR, Neurath MF (2006) In vivo diagnosis of collagenous colitis by confocal endomicroscopy. Gut 55:591–592
Kiesslich R, Goetz M, Schneider C et al (2005) Confocal endomicroscopy as a novel method to diagnose colitis associated neoplasias in ulcerative colitis: a prospective randomized trial [abstract]. Digestive Disease Week 2005. Gastroenterology 128:A35 [Suppl 2]
Kwiterovich KA, Maguire MG, Murphy RP, Schachat AP, Bressler NM, Bressler SB, Fine SL (1991) Frequency of adverse systemic reactions after fluorescein angiography. Results of a prospective study. Ophthalmology 98:1139–1142
Pacuriariu RI (1982) Low incidence of side effects following intravenous fluorescein angiography. Ann Ophtalmol 14:32–36
Polglase AL, McLaren W, Skinner SA, Kiesslich R, Neurath MF, Delaney PM (2005) A fluorescence confocal endomicroscope for in vivo microscopy of the upper-and lower-GI tract. Gastrointest Endosc 62:686–695
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© 2008 Springer Medizin Verlag Heidelberg
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Goetz, M., Dunbar, K., Canto, M.I. (2008). Examination Technique of Confocal Laser Endomicroscopy. In: Atlas of Endomicroscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35115-3_4
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DOI: https://doi.org/10.1007/978-3-540-35115-3_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-34757-6
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