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Melanoma of the Trunk and Limbs Including Superficial and Nodular Melanoma

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Abstract

Superficial and nodular melanoma of the trunk and limbs are the most frequent melanoma subtypes in Caucasians, and are largely responsible for the increased incidence of melanoma noted over the past few decades [1, 2]. Superficial spreading melanoma (SSM) is defined as an invasive melanoma that has an in-situ component beyond three rete ridges of its invasive component at the dermal layer. The radial growth phase of SSM is characterized by invasion of tumor cells both singly and in nests upward within the epidermis (pagetoid spread). In the natural progression of the neoplasm the melanoma will progress from the radial growth phase to the vertical growth phase. The SSM may arise in a preexisting nevus or de novo, and although a predilection for the trunk (the back of men) and limbs in women is documented, SSM can certainly develop at any site on the body [3, 4].

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(2007). Melanoma of the Trunk and Limbs Including Superficial and Nodular Melanoma. In: Soyer, H., Argenziano, G., Hofmann-Wellenhof, R., Johr, R. (eds) Color Atlas of Melanocytic Lesions of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35106-1_35

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