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TRPM8

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Transient Receptor Potential (TRP) Channels

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 179))

Abstract

Originally cloned as a prostate-specific protein, TRPM8 is now best known as a cold- and menthol-activated channel implicated in thermosensation. In this chapter we provide a brief review of current knowledge concerning the biophysical properties, gating mechanisms, pharmacology and (patho)physiology of this TRP channel.

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Authors and Affiliations

  1. Laboratory of Physiology, KU Leuven, Campus Gasthuisberg O&N, 3000, Leuven, Belgium

    T. Voets, G. Owsianik & B. Nilius

Authors
  1. T. Voets
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  2. G. Owsianik
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  3. B. Nilius
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Editor information

Editors and Affiliations

  1. Experimentele und Klinische, Pharmakologie und Toxikologie, Universität des Saarlandes, Gebäude 46, 66421, Homburg, Deutschland

    Veit Flockerzi

  2. Laboratorium voor Fysiologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, 3000, Leuven, België

    Bernd Nilius

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Voets, T., Owsianik, G., Nilius, B. (2007). TRPM8. In: Flockerzi, V., Nilius, B. (eds) Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-34891-7_20

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