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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 179))

Abstract

TRPM3 is the last identified member of the TRPM subfamily and is most closely related to TRPM1. Due to alternative splicing, the TRPM3 gene encodes a large number of different variants. One splice event, affecting the pore-forming region of the channel, changes its selectivity for divalent cations. Inthis review, we give an overview of the identified TRPM3 variants and compare their functional properties.

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© 2007 Springer-Verlag Berlin Heidelberg

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Oberwinkler, J., Philipp, S.E. (2007). TRPM3. In: Flockerzi, V., Nilius, B. (eds) Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-34891-7_15

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