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Alasalvar C, Grigor JM, Zhang D, Quantick PC, Shahidi F (2001) Comparison of volatilves, phenolics, sugars, antioxidant vitamins, and sensory quality of different colored carrot varieties. J Agri Food Chem 49:1410–1416
Arumuganathan K, Earle ED (1991) Nuclear DNA conents of some important plant species. Plant Mol Biol Rep 9:208–218
Bach IC, Olesen A, Simon PW (2002) PCR-based markers to differentiate the mitochondrial genome of petaloid and malefertile carrot (Daucus carota L.). Euphytica 127:353–365
Ballvora A, Hesselbach J, Niewohner J, Leister D, Salamini F, Gebhardt C (1995) Marker enrichment and high-resolution map of the segment of potato chromosome VII harbouring the nematode resistance gene Gro1. Mol Gen Genet 249:82–90
Banga O (1957a) The development of the original European carrot material. Euphytica 6:64–76
Banga O (1957b) Origin of the European cultivated carrot. Euphytica 6:54–63
Becker J, Vos P, Kuiper M, Salamini F, Heun M (1995) Combined mapping of AFLP and RFLP markers in barley. Mol Gen Genet 249:65–73
Bendahmane A, Kanyuka K, Baulcombe DC (1997) High-resolution genetical and physical mapping of the Rx gene for extreme resistance to potato virus × in tetraploid potato. Theor Appl Genet 95:153–162
Bennett MD, Leitch IJ (1995) Nuclear DNA amounts in angiosperms. Ann Bot 76:113–176
Boiteux LS (2000) Characterization of the Meloidogyne javanica resistance locus employing molecular markers and isolation of candidate disease resistance loci in the carrot (Daucus carota L.) genome. Dissertation, University of Wisconsin
Boiteux LS, Belter JG, Roberts PA, Simon PW (2000) RAPD linkage map of the genomic region encompassing the root-knot nematode (Meloidogyne javanica) resistance locus in carrot. Theor Appl Genet 100:439–446
Boiteux LS, Fonseca MEN, Simon PW (1999) Effects of plant tissue and DNA purification method on randomly amplified polymorphic DNA-based genetic fingerprinting analysis in carrot. J Am Soc Hort Sci 124:32–38
Boiteux LS, Hyman JR, Bach IC, Fonseca MEN, Matthews WC, Roberts PA, Simon PW (2004) Employment of flanking codominant STS markers to estimate allelic substitution effects of a nematode resistance locus in carrot. Euphytica 136:37–44
Borner T, Linke B, Nothnagel T, Scheike R, Schulz B, Steinborn R, Brennicke A, Stein M, Wricke G (1995) Inheritance of nuclear and cytoplasmic factors affecting male sterility in Daucus carota. Adv Plant Breed 18:111–122
Botstein D, White RL, Skolnick M, Davis RW (1980) Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Amer J Hum Genet 32:314–331
Bowes CE, Wolyn DJ (1998) Phylogenetic relationships among fertile and petaloid male-sterile accessions of carrot, Daucus carota L. Theor Appl Genet 96:928–932
Bradeen JM, Bach IC, Briard M, le Clerc V, Grzebelus D, Senalik DA, Simon PW (2002) Molecular diversity analysis of cultivated carrot (Daucus carota L.) and wild Daucus populations reveals a genetically nonstructured composition. J Am Soc Hort Sci 127:383–391
Bradeen JM, Simon PW (1998) Conversion of an AFLP fragment linked to the carrot Y2 locus to a simple, codominant, PCR-based marker form. Theor Appl Genet 97:960–967
Bradeen JM, Staub JE, Wye C, Antonise R, Peleman J (2001) Towards an expanded and integrated linkage map of cucumber (Cucumis sativus L.). Genome 44:111–119
Briard M, le Clerc V, Grzebelus D, Senalik D, Simon PW (2000) Modified protocols for rapid carrot genomic DNA extraction and AFLP analysis using silver stain or radioisotopes. Plant Mol Biol Rep 18:235–241
Brigneti G, Garcia Mas J, Baulcombe DC (1997) Molecular mapping of the potato virus Y resistance gene Rysto in potato. Theor Appl Genet 94:198–203
Bucci G, Kubisiak TL, Nance WL, Menozzi P (1997) A population consensus, partial linkage map of Picea abies Karst. based on RAPD markers. Theor Appl Genet 95:643–654
Buishand JG, Gabelman WH (1979) Investigations on the inheritance of color and carotenoid content in phloem and xylem of carrot roots (Daucus carota L.). Euphytica 28:611–632
Chandler GT, Plunkett GM (2004) Evolution in Apiales: nuclear and chloroplast markers together in (almost) perfect harmony. Bot J Linn Soc 144:123–147
Constance L (1971) History of the classification of Umbelliferae (Apiaceae). In: Heywood VH (ed.) The Biology and Chemistry of the Umbelliferae. Bot J Linn Soc, London, pp 1–8
Cronquist A (1981) An Integrated System of Classification of Flowering Plants. Columbia University Press, New York
Dahlgren RMT (1980) A revised system of classification of the angiosperms. Bot J Linn Soc 80:91–124
Davis TM, Yu H (1997) A linkage map of the diploid strawberry, Fragaria vesca. J Hered 88:215–221
Downham A, Collins P (2000) Coloring our foods in the last and next millennium. Intl J Food Sci Technol 35:5–22
Downie SR, Ramanath S, Katz-Downie DS, Llanas E (1998) Molecular systematics of Apiaceae subfamily Apioideae: phylogenetic analyses of nuclear ribosomal DNA internal transcribed spacer and plastid rpoC1 intron sequences. Am J Bot 85:563–591
Drude CGO (1898) Umbelliferae. In: Engler A, Prantl K (eds.) Die natürlichen Pflanzenfamilien, vol 3(8). Wilhelm Engelmann, Leipzig, Germany, pp 63–250
Echt CS, Erdahl LA, McCoy TJ (1992) Genetic segregation of random amplified polymorphic DNA in diploid cultivated alfalfa. Genome 35:84–87
Feher A, Pasternak TP, Dudits D (2003) Transition of somatic plant cells to an embryogenic state. Plant Cell Tiss Org Cult 74:201–228
Folkerts O, Hanson MR (1991) The male sterility-associated pcf gene and the normal atp9-1 gene in petunia are located on different mitochondrial DNA molecules. Genetics 129:885–895
Freeman RE, Simon PW (1983) Evidence for simple genetic control of sugar type in carrot (Daucus carota L.). J Am Soc Hort Sci 108:50–54
Grzebelus D, Senalik D, Jagosz B, Simon PW, Michalik B (2001) The use of AFLP markers for the identification of carrot breeding lines and F1 hybrids. Plant Breed 120:526–528
Hallden C, Hansen M, Nilsson NO, Hjerdin A (1996) Competition as a source of errors in RAPD analysis. Theor Appl Genet 93:1188–1192
Heinonen MI (1990) Carotenoids and provitamin A activity of carrot (Daucus carota L.) cultivars. J Agri Food Chem 38:609–612
Heun M, Helentjaris T (1993) Inheritance of RAPDs in F1 hybrids of corn. Theor Appl Genet 85:961–968
Heywood VH (1983) Relationships and evolution in the Daucus carota complex. Isr J Bot 32:51–65
Hirner AA, Veit S, Seitz HU (2001) Regulation of anthocyanin biosynthesis in UV-A-irradiated cell cultures of carrot and in organs of intact carrot plants. Plant Sci 161:315–322
Hoffmann-Sommergruber K, O’Riordain G, Ahorn H, Ebner C, Laimer da Camara Machado M, Puhringer H, Scheiner O, Breiteneder H (1999) Molecular characterization of Dau c 1, the Bet v 1 homologous protein from carrot and its cross-reactivity with Bet v 1 and Api g 1. Clin Exp Allergy 29:840–847
Huestis GM, McGrath JM, Quiros CF (1993) Development of genetic markers in celery based on restriction fragment length polymorphisms. Theor Appl Genet 85:889–896
Janska H, Mackenzie SA (1993) Unusual mitochondrial genome organization in cytoplasmic male-sterile common bean and the nature of cytoplasmic reversion to fertility. Genetics 135:869–879
Jiang C, Lewis ME, Sink KC (1997) Combined RAPD and RFLP molecular linkage map of asparagus. Genome 40:69–76
Judd WS, Sanders RW, Donoghue MJ (1994) Angiosperm family pairs: preliminary phylogenetic analyses. Harvard Papers Bot 5:1–51
Just B (2004) Genetic mapping of carotenoid pathway structural genes and major gene QTLs for carotenoid accumulation in wild and domesticated carrot (Daucus carota L.). Dissertation, University of Wisconsin, Madison
Kennard WC, Poetter K, Dijkhuizen A, Meglic V, Staub JE, Havey MJ (1994) Linkages among RFLP, RAPD, isozyme, disease-resistance, and morphological markers in narrow and wide crosses of cucumber. Theor Appl Genet 89:42–48
King JJ, Bradeen JM, Bark O, McCallum JA, Havey MJ (1998) A low-density genetic map of onion reveals a role for tandem duplication in the evolution of an extremely large diploid genome. Theor Appl Genet 96:52–62
Kubo T, Nishizawa S, Sugawara A, Itchoda N, Estiati A, Mikami T (2000) The complete nucleotide sequence of the mitochondrial genome of sugar beet (Beta vulgaris L.) reveals a novel gene for tRNACys(GCA). Nucl Acids Res 28:2571–2576
Kust AF (1970) Inheritance and differential formation of color and associated pigments in xymlem and phloem of carrot, Daucus carota, L. Dissertation, University of Wisconsin, Madison
le Clerc V, Briard M, Granger J, Delettre J (2003) Genebank biodiversity assessments regarding optimal sample size and seed harvesting techniques for the regeneration of carrot accessions. Biodiversity Conserv 12:2227–2236
Li X, van Eck HJ, Rouppe van der Voort JNAM, Huigen DJ, Stam P, Jacobsen E (1998) Autotetraploids and genetic mapping using common AFLP markers: the R2 allele conferring resistance to Phytophthora infestans mapped on potato chromosome 4. Theor Appl Genet 96:1121–1128
Lin H, Zhang L, Yang Z, Huang M, Wu N (2003) Molecular characterization of poly(A)-binding protein from Daucus carota. DNA Seq 14:147–153
Linke B, Nothnagel T, Borner T (2003) Flower development in carrot CMS plants: mitochondria affect the expression of MADS box genes homologous to GLOBOSA and DEFICIENS. Plant J 34:27–37
Mackill DJ, Zhang Z, Redona ED, Colowit PM (1996) Level of polymorphism and genetic mapping of AFLP markers in rice. Genome 39:969–977
Meksem K, Leister D, Peleman J, Zabeau M, Salamini F, Gebhardt C (1995) A high-resolution map of the vicinity of the R1 locus on chromosome V of potato based on RFLP and AFLP markers. Mol Gen Genet 249:74–81
Meyer K, Keil M, Naldrett MJ (1999) A leucine-rich repeat protein of carrot that exhibits antifreeze activity. FEBS Lett 447:171–178
Michelmore RW, Paran I, Kesseli RV (1991) Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations. Proc Natl Acad Sci USA 88:9828–9832
Morelock TE, Simon PW, Peterson CE (1996) Wisconsin wild: another petaloid male-sterile cytoplasm for carrot. HortScience 31:887–888
Mudge J, Andersen WR, Kehrer RL, Fairbanks DJ (1996) A RAPD genetic map of Saccharum officinarum. Crop Sci 36:1362–1366
Nagata R, Wada M, Satoh S, Kamada H, Harada H (1993) A cDNA differentially expressed between embryogenic and nonembryogenic carrot (Daucus carota L.) cells. Plant physiol 103:1021
Nakajima Y, Oeda K, Yamamoto T (1998) Characterization of genetic diversity of nuclear and mitochondrial genomes in Daucus varieties by RAPD and AFLP. Plant Cell Rep 17:848–853
Nakajima Y, Yamamoto T, Muranaka T, Oeda K (1999) Genetic variation of petaloid male-sterile cytoplasm of carrots revealed by sequence-tagged sites (STSs). Theor Appl Genet 99:837–843
Nakajima Y, Yamamoto T, Muranaka T, Oeda K (2001) A novel orfB-related gene of carrot mitochondrial genomes that is associated with homeotic cytoplasmic male sterility (CMS). Plant Mol Biol 46:99–107
Ojima A, Shiota H, Higashi K, Kamada H, Shimma Y, Wada M, Satoh S (1997) An extracellular insoluble inhibitor of cysteine proteinases in cell cultures and seeds of carrot. Plant Mol Biol 34:99–109
Paran I, Rouppe van der Voort J, Lefebvre V, Jahn M, Landry L, van Schriek M, Tanyolac B, Caranta C, Chaim AB, Livingstone K, Palloix A, Peleman J (2004) An integrated genetic map of pepper (Capsicum spp. ). Mol Breed 13:251–261
Peterson CE, Simon PW (1986) Carrot breeding. In: Bassett MJ (ed.) Breeding Vegetable Crops. AVI, Westport, CT, pp 321–356
Pimenov MG, Leonov MV (1993) The Genera of the Umbelliferae: a Nomenclator. Royal Botanical Gardens, Kew, UK
Plunkett GM, Soltis DE, Soltis PS (1996a) Evolutionary patterns in Apiaceae: inferences based on matK sequence data. Syst Bot 21:477–495
Plunkett GM, Soltis DE, Soltis PS (1996b) Higher level relationships of Apiales (Apiaceae and Araliaceae) based on phylogenetic analysis of rbcL sequences. Am J Bot 83:499–515
Plunkett GM, Soltis DE, Soltis PS (1997) Clarification of the relationship between Apiaceae and Araliaceae based on matK and rbcL sequence data. Am J Bot 84:565–580
Riedy MF, Hamilton WJ, Aquadro CF (1992) Excess of nonparental bands in offspring fromknown primate pedigrees assayed using RAPD PCR. Nucl Acids Res 20:918
Robison MM, Wolyn DJ (2002) Complex organization of the mitochondrial genome of petaloid CMS carrot. Mol Genet Genom 268:232–239
Rubatzky VE, Quiros CF, Simon PW (1999) Carrots and Related Vegetable Umbelliferae. CABI, New York
Rurek M, Szklarczyk M, Adamczyk N, Michalik B, Augustyniak H (2001) Differences in editing of mitochondrial nad3 transcripts from CMA and fertile carrots. Acta Biochim Polonica 48:711–717
Sáenz LaÃn C (1981) Research on Daucus L. (Umbelliferae). Anal Jardin Bot Madrid 37:481–533
Sano T, Nishimoto M, Saburi W, Kimura A, Yasuda H, Uchibatake M, Ohwada T, Masuda H (2004) Isolation and characterization of cDNA encoding P-19. 5 protein accumulated preferentially at early stage of carrot somatic embryogenesis. Plant Sci 167:1211–1217
Santos CAF, Simon PW (2002a) QTL analyses reveal clustered loci for accumulation of major provitamin A carotenes and lycopene in carrot roots. Mol Genet Genom 268:122–129
Santos CAF, Simon PW (2002b) Some AFLP amplicons are highly conserved DNA sequences mapping to the same linkage groups in two F2 populations of carrot. Genet Mol Biol 25:195–201
Santos CAF, Simon PW (2004) Merging carrot linkage groups based on conserved dominant AFLP markers in F2 populations. J Am Soc Hort Sci 129:211–217
Schmidt ED, Guzzo F, Toonen MA, de Vries SC (1997) Aleucinerice repeat containing receptor-like kinase marks somatic plant cells competent to form embryos. Development 124:2049–2062
Schulz B, Westphal L, Wricke G (1993) Linkage groups of isozymes, RFLP and RAPD markers in carrot (Daucus carota L. sativus). Euphytica 74:67–76
Schulz B, Westphal L, Wricke G (1994) Linkage groups of isozymes, RFLP and RAPD markers in carrot (Daucus carota L. sativus). Euphytica 74:67–76
Sebastian RL, Howell EC, King GJ, Marshall DF, Kearsey MJ (2000) An integrated AFLP and RFLP Brassica oleracea linkage map from two morphologically distinct doubled-haploid mapping populations. Theor Appl Genet 100:75–81
Sebkova V, Unger C, Hardegger M, Sturm A (1995) Biochemical, physiological, and molecular characterization of sucrose synthase from Daucus carota. Plant Physiol 108:75–83
Sharma AK, Bhattacharyya NK (1954) Further investigations on several genera of Umbelliferae and their relationship. Gentica 30:1–68
Simon PW (1992) Genetic improvement of vegetable carotene content. Biotechnology and Nutrition Third International Symposium, London 1992. Butterworth-Heinemann, London, pp 291–300
Simon PW (1996) Inheritance and expression of purple and yellow storage root color in carrot. J Hered 87:63–66
Simon PW (2000) Domestication, historical development, and modern breeding of carrot. Plant Breed Rev 19:157–190
Simon PW, Matthews WC, Roberts PA (2000) Evidence for simply inherited dominant resistance toMeloidogyne javanica in carrot. Theor Appl Genet 100:735–742
Simon PW, Rubatzky VE, Bassett MJ, Strandberg JO, White JM (1997) B7262, purple carrot inbred. Hort Science 32:146–147
Simon PW, Wolff XY (1987) Carotene in typical and dark orange carrots. J Agri Food Chem 35:1017–1022
Simpson KL (1983) Relative value of carotenoids as precursors of vitamin A. Am Proc Nutr Soc 42:7–17
Small E (1978) A numerical taxonomic analysis of the Daucus carota complex. Can J Bot 56:248–276
Smith MW, Ito M, Yamada T, Suzuki T, Komamine A (1993) Isolation and characterization of a cDNA clone for plant nuclear antigen 21D7 associated with cell division. Plant Physiol 101:809–817
Sondur SN, Manshardt RM, Stiles JI (1996) A genetic linkage map of papaya based on randomly amplified polymorphic DNA markers. Theor Appl Genet 93:547–553
St. Pierre MD, Bayer RJ (1991) The impact of domestication on the genetic variability in the orange carrot, cultivated Daucus carota ssp. sativus and the genetic homogeneity of various cultivars. Theor Appl Genet 82:249–253
St. Pierre MD, Bayer RJ, Weis IM (1990) An isozyme-based assessment of the genetic variability within the Dau cus carota complex (Apiaceae: Caucalideae). Can J Bot 68:2449–2457
Stam P (1993) Construction of integrated genetic linkage maps by means of a new computer package: Join Map. Plant J 3:739–744
Stintzing FC, Carle R (2004) Functional properties of anthocyanins and betalains in plants, food, and in human nutrition. Trends Food Sci Technol 15:19–38
Sturm A, Chrispeels MJ (1990) cDNA cloning of carrot extra-cellular beta-fructosidase and its expression in response to wounding and bacterial infection. Plant Cell 2:1107–1119
Sturm A, Hess D, Lee H, Lienhard S (1999a) Neutral invertase is a novel type of sucrose-cleaving enzyme. Physiol Plant 107:159–165
Sturm A, Lienhard S, Schatt S, Hardegger M (1999b) Tissuespecific expression of two genes for sucrose synthase in carrot (Daucus carota L.). Plant Mol Biol 39:349–360
Surles RL, Weng N, Simon PW, Tanumihardjo SA (2004) Carotenoid profiles and consumer sensory evaluation of specialty carrots (Daucus carota L.) of various colors. J Agri Food Chem 52:3417–3421
Szklarczyk M, Oczkowski M, Augustyniak H, Borner T, Linke B, Michalik B (2000) Organisation and expression of mitochondrial atp9 genes from CMS and fertile carrots. Theor Appl Genet 100:263–270
Takhtajan AL (1980) Outline of the classification of flowering plants (Magnoliophyta). Bot Rev 46:225–359
Tang G, Luscher M, Sturm A (1999) Antisense repression of vacuolar and cell wall invertase in transgenic carrot alters early plant development and sucrose partitioning. Plant Cell 11:177–189
Tang G, Sturm A (1999) Antisense repression of sucrose synthase in carrot (Daucus carota L.) affects growth rather than sucrose partitioning. Plant Mol Biol 41:465–479
Thormann CE, Ferreira ME, Camargo LEA, Tivang JG, Osborn TC (1994) Comparison of RFLP and RAPD markers for estimating genetic relationships within and among cruiferous species. Theor Appl Genet 88:973–980
Thorne RF (1968) Synopsis of a putatively phylogenetic classification of the flowering plants. Aliso 6:57–66
Unger C, Hardegger M, Lienhard S, Sturm A (1994) cDNA cloning of carrot (Daucus carota) soluble acid betafructofuranosidases and comparison with the cell wall isoenzyme. Plant Physiol 104:1351–1357
van den Berg H, Faulks R, Granado HF, Hirschberg J, Olmedilla B, Sandmann G, Southon S, Stahl W (2000) The potential for the improvement of carotenoid levels in foods and the likely systemic effects. J Sci Food Agri 80:880–912
Vavilov NI (1951) The origin, variation, immunity and breeding of cultivated plants. Chron Bot 13:1–366 (translated from Russian by Chester S)
Vivek BS, Simon PW (1999a) Linkage relationships among molecular markers and storage root traits of carrot (Daucus carota L. ssp. sativus). Theor Appl Genet 99:58–64
Vivek BS, Simon PW (1999b) Phylogeny and relationships in Daucus based on restriction fragment length polymorphisms (RFLPs) of the chloroplast and mitochondrial genomes. Euphytica 105:183–189
Vos P, Hogers R, Bleeker M, Reijans M, Lee T, Hornes M, Frijters A, Pot J, Peleman J, Kuiper M, Zabeau M (1995) AFLP: a new technique for DNA fingerprinting. Nucl Acids Res 23:4407–4414
Vuylsteke M, Mank R, Antonise R, Bastiaans E, Senior ML, Stuber CW, Melchinger AE, Lubbersted T, Xia XC, Stam P, Zabeau M, Kuiper M (1999) Two high-density AFLP linkage maps of Zeamays L.: analysis of distribution of AFLP markers. Theor Appl Genet 99:921–935
Welch JE, Grimball EL (1947) Male sterility in carrot. Science 106:594
Welsh RM (1997) Agronomic problems related to provitamin A carotenoid-rich plants. Eur J Clin Nutr 51:S34–S38
Westphal L, Wricke G (1991) Genetic and linkage analysis of isozyme loci in Daucus carota L. Euphytica 56:259–267
Westphal L, Wricke G (1997) Construction of a linkage map of Daucus carota L. sativus and its application for the mapping of disease resistance and restorer genes. J Appl Genet 38A:13–19
Williams JGK, Kubelik AR, Livak KJ, Rafalski JA, Tingey SV (1990) DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. Nucl Acids Res 18:6531–6535
Worrall D, Elias L (1998) A carrot leucine-rich-repeat protein that inhibits ice recrystallization. Science 282:115–117
Wurtele ES, Wang H, Durgerian S, Nikolau BJ, Ulrich TH (1993) Characterization of a gene that is expressed early in somatic embryogenesis ofDaucus carota. Plant Physiol 102:303–312
Yamato K, Ogura Y, Kanegae T, Yamada Y, Ohyama K (1992) Mitochondrial genome structure of rice suspension culture from cytoplasmic male-sterile line (A-58CMS): reappraisal of the master circle. Theor Appl Genet 83:279–288
Yang XF, Quiros CF (1995) Construction of a genetic linkage map in celery using DNA-based markers. Genome 38:36–44
Yau Y, Simon PW (2003) A 2.5-kb insert eliminates acid soluble invertase isozyme II transcript in carrot (Daucus carota L.) roots, causing high sucrose accumulation. Plant Mol Biol 53:151–162
Yau Y, Santos K, Simon PW (2005) Molecular tagging and selection for sugar type in carrot roots with codominant, PCR-based markers. Mol Breed 16:1–10
Zenkteler M (1962) Microsporogenesis and tapetal development in normal and male-sterile carrots (Daucus carota L.). Am J Bot 49:341–348
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Bradeen, J.M., Simon, P.W. (2007). Carrot. In: Kole, C. (eds) Vegetables. Genome Mapping and Molecular Breeding in Plants, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-34536-7_4
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