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Allergic and Pseudoallergic Reactions to Drugs

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Pediatric Allergy, Asthma and Immunology

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Abstract

The rapid development of new drugs to cure or control human illness corresponds to an expanding spectrum of adverse reactions to such agents. Before the introduction of sulfonamides in the late 1930s, the incidence of adverse drug reaction (ADR) approximated 0.5%–1.5% of all patients. Currently, 15%–30% of hospitalized patients experience an ADR [120]. The zenith is found in nurslings and toddlers. Drugs cause allergic and pseudoallergic reactions (PAR), even though other researchers, especially the Anglo-Americans, seem to consider it more suitable to call them ADRs, obviously shaped on the definition of adverse reactions to food, thus foregoing a pathogenic classification [2].

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(2008). Allergic and Pseudoallergic Reactions to Drugs. In: Pediatric Allergy, Asthma and Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33395-1_19

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