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Molecular Physiology of Toxin Production and Growth Regulation in Harmful Algae

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Ecology of Harmful Algae

Part of the book series: Ecological Studies ((ECOLSTUD,volume 189))

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References

  • Alpermann T, John U, Tillmann U, Evans K, Cembella A (2004) Genotypic and phenotypic variability in allelochemical potential within populations of Alexandrium tamarense. XI Inter Conf on Harmful Algal Blooms, Cape Town, South Africa (Abstract), p 57

    Google Scholar 

  • Barbier M, Leighfield TA, Soyer-Gobillard M-O, Van Dolah FM (2003) Expression of a cyclin B homologue in the cell cycle of the dinoflagellate, Karenia brevis. J Eukaryot Microbiol 50:123–131

    Article  PubMed  CAS  Google Scholar 

  • Bates SS (1998) Ecophysiology and metabolism of ASP toxin production. In: Anderson DM, Cembella AD, Hallegraeff GM (eds) Physiological ecology of harmful algal blooms. NATO ASI Series 41. Springer, Berlin Heidelberg New York, pp 405–426

    Google Scholar 

  • Bertomeu T, Morse D (2004) Isolation of a dinoflagellate mitotic cyclin by functional complementation in yeast. Biochem Biophys Res Comm 323:1172–1183

    Article  PubMed  CAS  Google Scholar 

  • Börner T, Dittmann E (2005) Molecular biology of cyanobacterial toxins. In: Huisman J, Matthijs HCP, Visser PM (eds) Harmful cyanobacteria. Springer, Berlin Heidelberg New York, pp 25–40

    Chapter  Google Scholar 

  • Cembella AD (1998) Ecophysiology and metabolism of paralytic shellfish toxins in marine microalgae. In: Anderson DM, Cembella AD, Hallegraeff GM (eds) Physiological ecology of harmful algal blooms. NATO ASI Series 41. Springer, Berlin Heidelberg New York, pp 381–403

    Google Scholar 

  • Cembella AD (2003) Chemical ecology of eukaryotic microalgae in marine ecosystems. Phycologia 42:420–447

    Article  Google Scholar 

  • Cembella AD, John U, Singh R, Walter J, MacKinnon S (2004) Molecular genetic analysis of spirolide biosynthesis in the toxigenic dinoflagellate Alexandrium ostenfeldii. XI Inter Conf on Harmful Algal Blooms, Cape Town, South Africa (Abstract), p 82

    Google Scholar 

  • Chan LL, Hodgkiss IJ, Lu S, Lo SC-L (2004) Use of two-dimensional gel electrophoresis proteome reference maps of dinoflagellates for species recognition of causative agents of harmful algal blooms. Proteomics 4:180–192

    Article  PubMed  CAS  Google Scholar 

  • Eschbach E, John U, Reckermann M, Cembella AD, Edvardsen B, Medlin LK (2005). Cell cycle dependent expression of toxicity by the ichthyotoxic prymnesiophyte Chrysochromulina polylepis. Aquat Microb Ecol 39:85–95

    Google Scholar 

  • Evans KM, Kühn SF, Hayes PK (2005) High levels of genetic diversity and low levels of genetic differentiation in North Sea Pseudo-nitzschia pungens (Bacillariophyceae) populations. J Phycol 41:506–514

    Article  CAS  Google Scholar 

  • John U, Groben R, Beszteri B, Medlin L (2004b) Utility of amplified fragment length polymorphisms (AFLP) to analyse genetic structures within the Alexandrium tamarense species complex. Protist 155:169–179

    Article  PubMed  CAS  Google Scholar 

  • John U, Tillmann U, Cembella A, Medlin L (2004a) Expression of polyketide synthases (PKS) during induction of toxicity in the ichthyotoxic prymnesiophyte Chrysochromulina polylepis. XI Inter Conf on Harmful Algal Blooms, Cape Town, South Africa (Abstract), p 147

    Google Scholar 

  • Leighfield TA, Van Dolah FM (1999) Cell cycle regulation in a dinoflagellate, Amphidinium operculatum: identification of the diel entraining cue and a possible role of cyclic AMP. J Exp Mar Biol Ecol 262:177–197

    Article  Google Scholar 

  • Lidie KB, Ryan JC, Barbier M, Van Dolah, FM (2005) Gene expression in Florida red tide dinoflagellate Karenia brevis: analysis of an expressed sequence tag library and development of DNA microarray. Mar Biotechnol Oct 2005, p 46

    Google Scholar 

  • Lin S, Carpenter EJ (1999) A PSTTLRE-form of cdc2-like gene in the marine microalga Dunaliella tertiolecta. Gene 239:39–48

    Article  PubMed  CAS  Google Scholar 

  • Lin S, Corstjens PLAM (2002) Molecular cloning and expression of the proliferating cell nuclear antigen from the coccolithophorid Pleurochrysis carterae (Haptophyceae). J Phycol 38:164–173

    Article  Google Scholar 

  • Macpherson GR, Burton IW, LeBlanc P, Walter JA, Wright JLC (2003) Studies of the biosynthesis of DTX-5a and DTX-5b by the dinoflagellate Prorocentrum maculosum: regiospecificity of the putative Baeyer-Villigerase and insertion of a single amino acid in a polyketide chain. J Org Chem 68:1659–1664

    Article  PubMed  CAS  Google Scholar 

  • O’Brian GR, Fakhoury AM, Payne GA (2003) Identification of genes differentially expressed during aflatoxin biosynthesis in Aspergillus flavus and Aspergillus parasiticus. Fungal Genet Biol 39:118–127

    Article  CAS  Google Scholar 

  • Pan Y, Bates S, Cembella AD (1998) Environmental stress and domoic acid production by Pseudo-nitzschia: a physiological perspective. Nat Tox 6:127–135

    Article  CAS  Google Scholar 

  • Plumley FJ (1997) Marine algal toxins: biochemistry, genetics and molecular biology. Limnol Oceanogr 42:1252–1264

    Article  CAS  Google Scholar 

  • Scholin CA, Doucette GJ, Cembella AD (2006) Prospects for developing automated systems for in situ detection of harmful algae and their toxins. In: Babin M, Roesler C, Cullen J (eds) HABwatch: monographs on oceanographic methodology. UNESCO, Paris, (in press)

    Google Scholar 

  • Scholin CA, Herzog M, Sogin M, Anderson DM (1994) Identification of group-and strain-specific genetic markers for globally distributed Alexandrium (Dinophyceae). 2. Sequence analysis of a fragment of the LSU rRNA gene. J Phycol 30:999–1011

    Article  CAS  Google Scholar 

  • Snyder VR, Guerrero MA, Sinigalliano CD, Winshell J, Perez R, Lopez JV, Rein KS (2005) Localization of polyketide synthase encoding genes to the toxic dinoflagellate Karenia brevis. Phytochemistry 66:1767–1780

    Article  PubMed  CAS  Google Scholar 

  • Taroncher-Oldenburg G, Anderson DM (2000) Identification and characterization of three differentially expressed genes, encoding S-adenosylhomocysteine hydrolase, methionine aminopeptidase, and a histone-like protein, in the toxic dinoflagellate Alexandrium fundyense. Appl Environ Microbiol 66:2105–2112

    Article  PubMed  CAS  Google Scholar 

  • Taroncher-Oldenburg G, Griner EM, Francis CA, Ward BB (2003) Oligonucleotide microarray for the study of functional gene diversity in the nitrogen cycle of the environment. Appl Environ Microbiol 69:1159–1171

    Article  PubMed  CAS  Google Scholar 

  • Wright JLC, Cembella AD (1998) Ecophysiology and biosynthesis of polyether marine biotoxins. In: Anderson DM, Cembella AD, Hallegraeff GM (eds) Physiological ecology of harmful algal blooms. NATO ASI Series 41. Springer, Berlin Heidelberg New York, pp 427–451

    Google Scholar 

  • Zhu G, LaGier MJ, Stejskal F, Millership JJ, Cai X, Keithly JS (2002) Cryptosporidium parvum: the first protist known to encode a putative polyketide synthase. Gene 298:79–89

    Article  PubMed  CAS  Google Scholar 

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Cembella, A., John, U. (2006). Molecular Physiology of Toxin Production and Growth Regulation in Harmful Algae. In: Granéli, E., Turner, J.T. (eds) Ecology of Harmful Algae. Ecological Studies, vol 189. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-32210-8_17

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