Abstract
The incidence of malignant melanoma is increasing dramatically in people with light-colored skin in all parts of the world [1]. In 2004, an estimated 55,000 Americans were diagnosed with cutaneous melanoma, and 7,900 died from the disease [2]. Melanoma prognosis is linked to the stage at diagnosis. Fortunately, most new patients are diagnosed early in the clinical course of disease, when it can be cured with excision of the primary tumor and sentinel lymphadenectomy. Histologie confirmation of diagnosis and microstaging with an accurate tumor thickness are essential before embarking on treatment [3, 4]. Invasive primary melanomas to a depth of 2.0 mm or less without ulceration and negative nodal metastases are essentially curable, whereas melanomas of increasing depth become progressively less curable [4, 5]. Thus, the relationship between tumor thickness and 10-year survival rates is pivotal [5].
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Reinhardt, M.J. (2008). Cutaneous Melanoma. In: Dresel, S. (eds) PET in Oncology. Recent Results in Cancer Research, vol 170. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-31203-1_12
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DOI: https://doi.org/10.1007/978-3-540-31203-1_12
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