Abstract
The management of peritoneal metastases remains one of the most challenging problems in clinical oncology. Over the last decade, interest in the use of aggressive cytoreductive surgery combined with intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) has increased. This interest has been fueled by data from single institutions and collected series demonstrating long-term survival for selected patients with peritoneal surface metastases treated with this combined modality approach. Along with the availability of new cytotoxic and biological therapies for gastrointestinal cancers, recent data demonstrating the value of intraperitoneal therapy for ovarian cancer have provided new energy to investigations of HIPEC. Despite the proliferation of single-institution studies, there has been only a single large randomized study of HIPEC in colon carcinoma.
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© 2007 Springer-Verlag Berlin Heidelberg
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Sarnaik, A.A., Sussman, J.J., Ahmad, S.A., McIntyre, B.C., Lowy, A.M. (2007). Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques. In: González-Moreno, S. (eds) Advances in Peritoneal Surface Oncology. Resent Results in Cancer Research, vol 169. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-30760-0_6
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DOI: https://doi.org/10.1007/978-3-540-30760-0_6
Publisher Name: Springer, Berlin, Heidelberg
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