Neurobiological Foundation for the Meaning of Information

  • Walter J. Freeman
Part of the Lecture Notes in Computer Science book series (LNCS, volume 3316)


Brains create meaning and express it in information. They select and pre-process the information carried by sensory stimuli as sense data, from which they construct meaning. They post-process cognitive meaning into informative commands that control the goal-directed actions that express meaning. Meaning exists in the interaction of subjects with their environments. The process of perception by which brains construct meaning from information can be explained by analyzing the neural activity in human and animal brains as subjects engage in meaningful behaviors. Measurement is followed by decomposition and modeling of the neural activity in order to deduce brain operations. Brains function hierarchically with neuronal interactions within and between three levels: microscopic of single neurons, mesoscopic of local networks forming modules, and macroscopic of the global self-organization of the cerebral hemispheres by the organic unity of neocortex. Information is carried in continuous streams of microscopic axonal pulses. Meaning is carried in mesoscopic local mean fields of dendritic currents in discontinuous frames resembling cinemas, each frame having a spatial pattern of amplitude modulation of an aperiodic carrier wave.


Phase Velocity Amplitude Modulation Chaotic Attractor Gamma Oscillation Primary Sensory Cortex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Walter J. Freeman
    • 1
  1. 1.Department of Molecular and Cell BiologyUniversity of CaliforniaBerkeleyUSA

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