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In Vitro Translation-Based Computations

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Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2943))

Abstract

The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5’-end to 3’-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coliin vitro translation system with four-base codons.

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References

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© 2004 Springer-Verlag Berlin Heidelberg

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Sakakibara, Y., Hohsaka, T. (2004). In Vitro Translation-Based Computations. In: Chen, J., Reif, J. (eds) DNA Computing. DNA 2003. Lecture Notes in Computer Science, vol 2943. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-24628-2_19

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  • DOI: https://doi.org/10.1007/978-3-540-24628-2_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20930-0

  • Online ISBN: 978-3-540-24628-2

  • eBook Packages: Springer Book Archive

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