A Membrane System for the Leukocyte Selective Recruitment

  • Giuditta Franco
  • Vincenzo Manca
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2933)


A formal description is developed for the phenomenon of leukocyte recruitment that plays a critical role in the immune response. Due to its complex nature and capability to rapidly adapt to the attack of infectious agents, the immune system may be considered a typical example of complex adaptive system [9].

Here the leukocyte selective recruitment, crucial in immunity, is modeled as a dynamical system of interactions between leukocytes and endothelial cells, where a special kind of membrane structure turns out to be a very useful tool in the formal analysis of the recruitment process. In our membrane system, besides the traditional rules for communication and transformation of P systems [8], rules are allowed for the expression of receptors, for adhesion between membranes, and for the encapsulation of a membrane inside another membrane.


Membrane System Complex Adaptive System Leukocyte Recruitment Traditional Rule Leukocyte Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Giuditta Franco
    • 1
  • Vincenzo Manca
    • 1
  1. 1.Dipartimento di InformaticaUniversità di VeronaItaly

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