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Abstract

Among the primary risk factors of coronary heart disease hypercholesterolemia, hypertension and nicotine abuse take highest precedence. A total cholesterol level > 300 mg/dl signifies a high atherogenic risk for the individual in question. However, hypercholesterolemia (> 300 mg/dl) is observed in only approx. 25% of all patients with CHD (1). The majority of patients with coronary heart disease exhibit a total cholesterol level between 240 and 300 mg/dl. Corresponding to the results of the Framingham Study the distribution curve for total serum cholesterol in probands who have developed CHD overlaps considerably with that of probands who exhibited no coronary heart disease (1). The average cholesterol value of probands suffering from coronary heart disease was 255 mg/dl (219 mg/dl in probands who did not develop CHD) (1). Taking these results as a basis, it is not possible in an individual case with a total cholesterol level between 150 and 300 mg/dl to make a statement regarding the coronary risk only on the basis of determining the total cholesterol.

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© 1983 Westdeutscher Verlag GmbH, Opladen

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Assmann, G., Schriewer, H., Juchem, K.H. (1983). The Role of HDL Cholesterol in Preventive Medicine. In: Clinical Implications of Recent Research Results in Arteriosclerosis. Abhandlungen der Rheinisch-Westfälischen Akademie der Wissenschaften, vol 70. VS Verlag für Sozialwissenschaften, Wiesbaden. https://doi.org/10.1007/978-3-322-98699-3_27

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  • DOI: https://doi.org/10.1007/978-3-322-98699-3_27

  • Publisher Name: VS Verlag für Sozialwissenschaften, Wiesbaden

  • Print ISBN: 978-3-322-98700-6

  • Online ISBN: 978-3-322-98699-3

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