Skip to main content
SpringerLink
Log in

Polynucleotide (Nucleinsäuren)

  • Chapter
Book cover Biopolymere

Part of the book series: Teubner Studienbücher Chemie ((TSBC))

  • 220 Accesses

Zusammenfassung

Vom Standpunkt der Polymerchemie aus gesehen, handelt es sich bei den Polynucleotiden (Pn) um lineare Polyester aus Orthophosphorsäure und einer Pentose (D-Desoxyribose oder D-Ribose), die in der 1’-Position des Zuckerrestes N-ß-glykosidisch mit einer Purin- oder Pyrimidinbase als Seitengruppe verknüpft sind (Abb. 2.1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 49.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur Polynucleotide

  1. Miescher, F., Hoppe-Seyler’s Med.-ehem.Untersuchungen 1871, 441–460

    Google Scholar 

  2. Harbers, E., Nucleinsäuren, Thieme Verlag, Stuttgart, 2.Aufl. 1975

    Google Scholar 

  3. Beyersmann, D., Nucleinsäuren, Verlag Chemie, Heidelberg 1971

    Google Scholar 

  4. Doenecke, D., Naturwiss.Rdsch. 36, 432–438 (1983)

    Google Scholar 

  5. Avery, O.T., MacLeod, C.M., McCarty, M., J.Exp.Med. 79, 137 (1944)

    Google Scholar 

  6. Agarwal, K.L., Yamazaki, A., Cashion, P.J., Khorana, H.G., Angew.Chem. 84,489–, 498 (1972)

    Google Scholar 

  7. Sinha, N.D., Biernat, J., McManus, J., Köster, H., Nucleic Acids Res. 12, 4539–4557 (1984)

    Google Scholar 

  8. Engels, J.W., Uhlmann, E., Angew.Chem.101, 733–752 (1987)

    Google Scholar 

  9. Razin, A., Riggs, A.D., Science 210, 604–610 (1980)

    Google Scholar 

  10. Doerfler, W., Angew.Chem. 96, 917–929 (1984)

    Google Scholar 

  11. Chargaff, E., Experientia 6, 201–209 (1950)

    Google Scholar 

  12. Walton, G., Blackwell, J., Biopolymers, Academic Press, New York & London 1973, S. 514–546

    Google Scholar 

  13. Wyatt, G.R., Biochem.J.48 583–590 (1951)

    Google Scholar 

  14. Chargaff, E., Lipschitz, R., J.Am.Chem.Soc. 75, 3658–3661 (1953)

    Google Scholar 

  15. Vischer, E., Zamenhof, S., Chargaff, E., J.Biol.Chem. 177, 429–438 (1949)

    Google Scholar 

  16. Gandelman, B., Zamenhof, S., Chargaff, E., Biochim. Biophys.Acta 9, 399–401 (1952)

    Google Scholar 

  17. Hershey, E.D., Meiechen, N.E., Virology 3, 203 (1957)

    Google Scholar 

  18. Sinsheimer, R.L., J.Mol.Biol. 1, 43–53 (1959)

    Google Scholar 

  19. Volkin, E., Carter, C.E., J.Am.Chem.Soc. 73, 1516–1519 (1951)

    Google Scholar 

  20. Crosbie, G.W., Smellie, R.M.S., Davidson, N., Biochem. J. 54, 287–292 (1953)

    Google Scholar 

  21. Chargaff, E., Magsanik, B., Vischer, E., Green, C., Doninger, R., Elson, D., J.Biol.Chem. 186, 51–67 (1953)

    Google Scholar 

  22. Knight, C.A., J.Biol.Chem. 171, 297–308 (1948)

    Google Scholar 

  23. Elson, D., Chargaff, E., Biochim.Biophys.Acta 17, 367–376 (1955)

    Google Scholar 

  24. Astbury, W.T., Bell, F.O., Nature 141, 747ff. (1938)

    Google Scholar 

  25. Astbury, W.T., Cold Spring Harbor Symp.Quant.Biol. 6 109ff. (1938)

    Google Scholar 

  26. Cochran, W., Crick, F.C.H., Vand, V., Acta Crystallogr. 5, 581–586 (1952)

    Google Scholar 

  27. Watson, J.D., Crick, F.C.H., Nature 171, 737–738, 964–967 (1953)

    Google Scholar 

  28. Mitsui, Y., Langridge, R., Shortle, B.E., Cantor, C.R., Grant, R.C., Kodama, M., Wells, R.D., Nature 228, 1166–1169 (1970)

    Google Scholar 

  29. Pohl, F.M., Jovin, T.M., J.Mol.Biol. 67, 375–396 (1972)

    Google Scholar 

  30. Saenger, W., Principles of Nucleic Acid Structure, Springer Verlag, New York, Berlin, Heidelberg, Tokyo 1984

    Google Scholar 

  31. Langridge, R., Wilson, H.R., Hooper, C.W., Wilkins, M.H.F., Hamilton, L.D., J.Mol.Biol. 2, 19–37 (1960)

    Google Scholar 

  32. Marvin, D.A., Spencer, M., Wilkins, M.H.F., Hamilton, L.D., J.Mol.Biol. 3, 547–565 (1961)

    Google Scholar 

  33. Wilkins, M.H.F., Stokes, A.R., Wilson, H.R., Nature 171, 738–740 (1953)

    Google Scholar 

  34. Füller, W., Wilkins, M.H.F., Wilson, H.R., Hamilton, L.D., Arnott, S., J.Mol.Biol. 12, 60–80 (1965)

    Google Scholar 

  35. Arnott, S., in:Proceedings of the First Cleveland Symposium of Macromolecules (Herausg.: A. Walton), Elsevier, Amsterdam, Oxford, New York 1977, S. 87–104

    Google Scholar 

  36. Dickerson, R.E., Scientific American 249 (6), 86–102 (1983)

    Google Scholar 

  37. Sundaralingam, M., in: Structure and Conformation of Nucleic Acids and Protein-Nucleic Interactions (Herausg.: M. Sundaralingam, S.T. Rao), University Park Press, Baltimore 1975

    Google Scholar 

  38. Wang, A.H., Quigley, G.J., Kolpak, F.J., Crawford, J.L., van Boom, J.H., Van der Marel, G., Rieh, A., Nature 282, 680–686 (1979)

    Google Scholar 

  39. Wang, A.H., Quigley, G.J., Kolpak, F.J., van der Marel, G., van Boom, J.H., Rieh, A., Science 211, 171–176 (1981)

    Google Scholar 

  40. Gessner, R.V., Frederick, C.A., Quigley, G.J., Rieh, A., Wang, A.H.-J., J.Biol.Chem.264, 7921–7935 (1989)

    Google Scholar 

  41. Conner, B.N., Takano, T., Tanaka, S., Itakura, K., Dickerson, R.E., Nature 295, 294–299 (1982)

    Google Scholar 

  42. Wang, H.J., Fujii, S., van Boom, J.H., Rieh, A., Proc. Nat1.Acad.Sci.USA 79, 3964–3972 (1982)

    Google Scholar 

  43. Drew, H., Takano, T., Tanaka, S., Itakura, K., Dickerson, R.E., Nature 286 567–573 (1980)

    Google Scholar 

  44. Pohl, F.M., Nature 260, 365–366 (1976)

    Google Scholar 

  45. Hall, K.B., Maestre, M.F., Biopolymers 23, 2127–2139 (1984)

    Google Scholar 

  46. Härder, M.E., Johnson, W.C.jr., Nucleic Acids Res. 18, 2141–2148 (1990)

    Google Scholar 

  47. Behe, M., Felsenfeld, G.F., Proc.Natl.Acad.Sci.USA 78, 1619–1623 (1981)

    Google Scholar 

  48. Chaires, J.B., Biochemistry 24, 7479–7485 (1985)

    Google Scholar 

  49. Chen, F.-M., Nucleic Acids Res. 14, 5081–5097 (1986)

    Google Scholar 

  50. Devarajan, S., Shafer, R.H., Nucleic Acids Res. 14, 5099–5109 (1986)

    Google Scholar 

  51. Zhong, L., Johnson, W.C.jr., Biopolymers 30 821–828 (1990)

    Google Scholar 

  52. Vertino, P.M., Bergeron, R.J., Cavanaugh, P.F.jr., Porter, C.W., Biopolymers 26, 691–703 (1987)

    Google Scholar 

  53. Thomas, T.J., Gunnia, U.B., Thomas, T., J.Biol.Chem. 266, 6137–6141 (1991)

    Google Scholar 

  54. Takeuchi, H., Hanamura, N., Hayasaka, H., Harada, I., FEBS Letters 279, 253–255 (1991)

    Google Scholar 

  55. Jaworski, A., Hsieh, W.T., Blaho, J.A., Larson, J.E., Wells, R.D., Science 238, 773–777 (1987)

    Google Scholar 

  56. Lesnik, E.A., Bes’chetnikoba, Zh.A., Maslova, R.N., Varshavsky, Ja.M., FEBS Letters 280, 91–93 (1991)

    Google Scholar 

  57. Falk, M., Hartmann, K.A.jr., Lord, R.C., J.Am.Chem. Soc. 85, 387–391, 391–394 (1963)

    Google Scholar 

  58. Wolf, B., Hanion S., Biochemistry 14, 1661–1670 (1975)

    Google Scholar 

  59. Tao, N.J., Lindsay, S.M., Rupprecht, A., Biopolymers 28, 1019–1030 (1989)

    Google Scholar 

  60. Kopka, M.L., Fratini, A.V., Drew, H.R., Dickerson, R.E., J.Mol.Biol. 163, 129–146 (1983)

    Google Scholar 

  61. Umehara, T., Kuwabara, S., Mashimo, S., Yagihara, S., Biopolymers 30, 649–656 (1990)

    Google Scholar 

  62. De Voe, H., Tinoco, I.jr., J.Mol.Biol. 4, 518 (1962)

    Google Scholar 

  63. Marmur, J., Doty, P., Nature 183, 1427–1429 (1959)

    Google Scholar 

  64. Marmur, J., Doty, P., J.Mol.Biol. 5, 109–118 (1962)

    Google Scholar 

  65. Sueoka, N., Marmur, J., Doty, P., Nature 183, 1429–1431 (1959)

    Google Scholar 

  66. Frisman, V., Veselkov, V.S., Slonitsky, S.V., Karavaev, L.S., Varoblev, Biopolymers 13, 2169–2178 (1974)

    Google Scholar 

  67. Langlais, M., Tajmir-Riahl, K.A., Savoie, R., Biopolymers 30, 743–752 (1990)

    Google Scholar 

  68. Devarajan, S., Pattabiraman, N., Shafer, R.H., Biopolymers 27, 187–200 (1988)

    Google Scholar 

  69. Lerman, L.S., J.Mol.Biol. 3, 18–30 (1961)

    Google Scholar 

  70. Lerman, L.S., Proc.Natl.Acad.Sci.USA 49, 94–102 (1963)

    Google Scholar 

  71. Gabbay, E.J., Scotfield, R.E., Baxter, C.S., J.Am. Chem.Soc 95, 7850–7857 (1973)

    Google Scholar 

  72. Förster, W., Stutter, E., Int.J.Biol.Macromol. 6, 114–124 (1984)

    Google Scholar 

  73. Prabhakaran, M., Harvey, S.C., Biopolymers 27, 1239–1248 (1988)

    Google Scholar 

  74. Xodo, L.M., Manzini, G., Ruggiero, J., Quadrifoglio, F., Biopolymers 27, 1839–1857 (1988)

    Google Scholar 

  75. Zimmermann, H.W., Angew.Chem. 98, 115–131 (1986)

    Google Scholar 

  76. Chou, K.C., Mao, B., Biopolymers 27, 1795–1815 (1988)

    Google Scholar 

  77. Grivell, L.A., Scientific American 248 (3), 60–73 (1983)

    Google Scholar 

  78. Holley, R.W., Apgar, J., Everett, G.A., Madison, J.T., Marquises, M., Merrill, S.H., Penswick, J.R., Zamir, A., Science 147, 1462–1465 (1965)

    Google Scholar 

  79. McCloskey, J.A., Nishimura, S., Acc.Chem.Res. 10, 403–410 (1977)

    Google Scholar 

  80. Levitt, M., Nature 224, 759–763 (1969)

    Google Scholar 

  81. Zachau, H.G., Dütting, D., Feldmann, H., Hoppe-Seylers Z.physiol.Chem. 347, 212–235 (1966)

    Google Scholar 

  82. Zachau, H.G., Dütting, D., Feldman, H., Melchers, F., Karare, W., Cold Spring Harbor Symp.Quant.Biol. 31, 417 (1966)

    Google Scholar 

  83. Johnson, C.D., Adolph, K., Rosa, J.J., Hall, M.D., Sigler, P., Nature 226, 1246–1247 (1970)

    Google Scholar 

  84. Kim, S.H., Quigley, G.J., Suddath, F.L., McPherson, A., Sneden, D., Kim, J.J., Weinzierl, J., Rieh, A., Science 179, 285–288 (1972)

    Google Scholar 

  85. Schevitz, R.W., Podjarny, A.D., Krishnamachari, N., Hughes, J.J., Sigler, P.B., Sussman, J.L., Nature 278, 188–190 (1979)

    Google Scholar 

  86. Woo, N.H., Roe, B.A., Rieh, A., Nature 286, 346–351 (1980)

    Google Scholar 

  87. Moras, D., Comarmond, M.B., Fischer, J., Weiss, R., Thierry., Ebel, J.P., Giege, R., Nature 288, 669–674 (1980)

    Google Scholar 

  88. Quigley, G.J., Wang, A.J.H., Seeman, N.C., Suddath, F.C., Rieh, A., Sussman, J.L., Kein, S.H., Proc.Natl. Acad.Sci.USA 72, 4866–4870 (1975)

    Google Scholar 

  89. Reith, G., Picaud, F., Weissenbach, J., Ebel, P.J., Petrissant, G., Dirheimer, G., FEBS Letters 31, 345–347 (1973)

    Google Scholar 

  90. Schernau, U., Ackermann, T., Biopolymers 16, 1735–1745 (1977)

    Google Scholar 

  91. Schott, F.J., Grubert, M., Wangler, W., Ackermann, T., Biophysical Chemistry 14,25–30 (1981)

    Google Scholar 

  92. Diener, T.O., Ann.Rev.Microbiol. 28, 23–39 (1974)

    Google Scholar 

  93. Wild, U., Ramm, K., Sänger, H.L., Riesner, D., Europ. J.Biochem.103, 227–235 (1980)

    Google Scholar 

  94. Riesner, D., Steger, G., Schuhmacher, J., Gross, H.J., Randles, J.W., Sänger, H.L., Biophys.Struct.Mech. 9, 145–170 (1983)

    Google Scholar 

  95. Riesner, D., Gross, H.J., Ann.Rev.Biochem. 54, 531–564 (1985)

    Google Scholar 

  96. Mills, D.R., Kramer, F.R., Spiegelmann, S., Science 180, 916–927 (1973)

    Google Scholar 

  97. Stryer, Biochemie, Verlag Spektrum der Wissenschaft, Heidelberg 1990

    Google Scholar 

  98. Fiers, W., Contreras, R., Duerinck, F., Haegmean, G., Merregaert, J, Min Jou, W., Raeymakers, A., Volckaert, G., Ysebaert, M., Van de Kerckhove, J., Nolf, F., Van Montagu, M., Nature 256, 273–278 (1975)

    Google Scholar 

  99. Fiers, W., Medizin in unserer Zeit 1, 10–17 (1977)

    Google Scholar 

  100. Raviprakash, K.S., Cherayil, J.D., Int.J.Biol.Macro- mol. 7, 230–234 (1985)

    Google Scholar 

  101. Fukushima, T., Nitta, K., Sugai, Sh., Int.J.Biol. Macromol. 10, 25–33 (1988)

    Google Scholar 

  102. Davis, D.R., Ann.Rev.Biochem. 36, 321–364 (1967)

    Google Scholar 

  103. Fresco, J., Trans.N.Y.Acad.Sei. 21, 653 (1959)

    Google Scholar 

  104. Felsenfeld, G., Rieh, A., Biochim.Biophys.Acta 26, 425 (1957)

    Google Scholar 

  105. Krakauer, H., Sturtevant, J.M., Biopolymers 6, 491–512 (1968)

    Google Scholar 

  106. Goldstein, B., Biopolymers 12, 461–475 (1973)

    Google Scholar 

  107. Neumann, E., Ackermann, T., J.Phys.Chem. 73, 2170–2178 (1969)

    Google Scholar 

  108. Ackermann, T., Angew.Chem. 101, 1005–1016 (1989)

    Google Scholar 

  109. Hinz, H.-J., Haar, W., Ackermann, T., Biopolymers 9, 923–936 (1970)

    Google Scholar 

  110. Darneil, J.E., Wall, R., Tushinski, R.J., Proc.Nat. Acad.Sci.USA 68, 1321–1325 (1971)

    Google Scholar 

  111. Hozumi, N., Haruna, I., Watanabe, I., Mikoshiba, K., Tsukada, Y., Nature, 256, 337–339 (1975)

    Google Scholar 

  112. Mikoshiba, K.,Tsukada, Y., Haruna, I., Watanabe, I., Nature, 249, 445–448 (1974)

    Google Scholar 

  113. Uesugi, S., Ohkubo, M., Urata, H., Ikehara, M., Kobayashi, Y., Kyogoku, Y., J.Am.Chem.Soc. 106, 3675–3676 (1984)

    Google Scholar 

  114. Hall, K., Cruz, P., Tinoco, W.C.jr., Jovin, T.M., van de Sande, Nature 311, 584–586 (1984)

    Google Scholar 

  115. Adamiak, R.W., Galat, A., Skalski, B., Biochim. et Biophys.Acta 825, 345–352 (1985)

    Google Scholar 

  116. Davis, P.W., Adamiak, R.W., Tinoco, J.jr., Biopolymers 29, 109–122 (1990)

    Google Scholar 

  117. Tilghman, S.M., Tiemeier, D.C., Polski, F., Edgell, M.H., Seidman, J.G., Leder, A., Enquist, J.G., Norman, B., Leder, P., Proc.Natl.Acad.Sci.USA 74, 4406–4410 (1977)

    Google Scholar 

  118. Tilghman, S.M., Curtis, P.J., Tiemeyer, D.C., Leder, P., Weissmann, C., Proc.Natl.Acad.Sci.USA 75, 1309–1313 (1978)

    Google Scholar 

  119. Williamson, B., Nature 270, 295–297 (1977)

    Google Scholar 

  120. Darnell, J.E., Scientific American 249 (4), 72–82 (1983)

    Google Scholar 

  121. Chambon, P., Spektrum der Wissenschaft 1981, 104–117

    Google Scholar 

  122. Cech, T.R., Zaug, A.J., Grabowski, P.J., Cell 27, 487- (1981)

    Google Scholar 

  123. Zaug, A.J., Cech, T.R., Science 231, 470–475 (1986)

    Google Scholar 

  124. Cech, T.R., Spektrum der Wissenschaft 1987, 42–51

    Google Scholar 

  125. Cech, T.R., Angew.Chem.102 745–755 (1990)

    Google Scholar 

  126. Altman, S., Angew.Chem.102, 735–744 (1990)

    Google Scholar 

  127. Herschlag, D., Cech, T.R., Nature 344, 405–409 (1990)

    Google Scholar 

  128. Gassen, H.G., Angew.Chem.94, 15–27 (1982)

    Google Scholar 

  129. Wittmann, H.G., Biol.Chem.Hoppe-Seyler 370, 87–99 (1989)

    Google Scholar 

  130. Green, M., Mazarella, R.A., in Polymers: Biomaterials and Medical Applications (Herausg.: Jaqueline E. Kroschwitz), John Wiley & Sons, New York, Chichester, Brisbane, Toronto, Singapore 1989, S.474–496

    Google Scholar 

  131. Giri, L., Hill, W.E., Wittmann, H.G., Wittmann- Liebold, B., Advances in Protein Chemistry 36, 1–78, 1984

    Google Scholar 

  132. Wittmann, H.G., Wittmann-Liebold B., Cold Harbor Symp. 31, 163 (1966)

    Google Scholar 

  133. Lehninger, A.L., Biochemie, Verlag Chemie, Weinheim, 2.Auflage 1977, S. 763ff

    Google Scholar 

  134. Nierhaus, K.H., Rheinberger, H.J., Geigenmüller, U., Gnirke, A., Saruyama, H., Schilling, S., Wurmbach, P., in “Structure, Function and Genetics of Ribosomes” (Herausg.: B.Hardesty, G.Kramer) Springer-Verlag, Heidelberg 1986, S.454–472

    Google Scholar 

  135. Jacob, F., Monod, J., J.Mol.Biol. 3, 318–356 (1961)

    Google Scholar 

  136. Göhrisch, H., Forum Mikrobiologie 6, 210–220 (1983)

    Google Scholar 

  137. Ptashne, M., Johnson, A.D., Pabo, C.O., Spektrum der Wissenschaft 1983, 30–40

    Google Scholar 

  138. Pabo, C.O., Sauer, R.T., Ann.Rev.Biochem. 53, 293–321 (1984)

    Google Scholar 

  139. Sauer, R.T., Jordan, S.R., Pabo, C.O., Advances in Protein Chemistry 40, 2–61 (1990)

    Google Scholar 

  140. Lipman, F., Acc.Chem.Res. 6, 361–367 (1973)

    Google Scholar 

  141. Kleinkauf, H., Chemie in unserer Zeit 14, 105–114 (1980)

    Google Scholar 

  142. Kleinkauf, H., von Döhren, H., Current Topics Microbiol.Immunol. 91, 129–177 (1981)

    Google Scholar 

  143. Naturwissensch.Rdsch. 40, 104 (1987)

    Google Scholar 

  144. Brennicke, A., Naturwiss.Rdsch. 40, 394–396 (1987)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Universität Marburg, Deutschland

    Prof. Dr. rer. nat. Gotthold Ebert

Authors
  1. Prof. Dr. rer. nat. Gotthold Ebert
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1992 B. G. Teubner Stuttgart

About this chapter

Cite this chapter

Ebert, G. (1992). Polynucleotide (Nucleinsäuren). In: Biopolymere. Teubner Studienbücher Chemie. Vieweg+Teubner Verlag. https://doi.org/10.1007/978-3-322-92132-1_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-322-92132-1_2

  • Publisher Name: Vieweg+Teubner Verlag

  • Print ISBN: 978-3-519-03516-9

  • Online ISBN: 978-3-322-92132-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation