Zusammenfassung
Das Spektrum der Glukose-Stoffwechselstörungen durch Neuroleptika reicht von Störungen des Glukose-Toleranztests mit Hyperglykämie über pharmakogen induzierten Diabetes mellitus Typ II bis hin zu ketoazidotischen Zuständen. Keineswegs werden diese Stoffwechselstörungen nur durch atypische Neuroleptika ausgelöst. Zwar werden die meisten Fälle für Clozapin, gefolgt von Olanzapin, berichtet, aber auch unter Phenothiazinen und Lithium sind solche Fälle bekannt geworden (Naber et al., 2000). Wie Henderson (2002) anmerkt, wirken die Berichte über Glukose-Stoffwechselstörungen auf erfahrenere Psychiater wie Déjàvu-Erlebnisse, stand doch die Diskussion solcher Effekte bereits bei der Einführung der Phenothiazine vor mehr als 50 Jahren im Mittelpunkt des Interesses.
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Volz, HP. (2004). Störungen des Glukose-Stoffwechsels und Gewichtsveränderungen. In: Volz, HP., Kasper, S., Möller, HJ. (eds) Kasuistische Beiträge zur modernen Pharmakotherapie mit Quetiapin. Deutscher Universitätsverlag. https://doi.org/10.1007/978-3-322-83447-8_3
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DOI: https://doi.org/10.1007/978-3-322-83447-8_3
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