Abstract
Finely dispersed (particle size less than 100 nm) NaYF4:Yb3+,Er3+ and YF3:Yb3+,Er3+ phosphors are synthesized using a hydrothermal method. YF3:Yb3+,Er3+ phosphor is found to be mostly appropriate for IR radiation based photodynamic therapy (PDT). The efficiency of infrared laser stimulated generation of singlet (active) oxygen by a drug composition containing YF3:Yb3+,Er3+ phosphor and “Radachlorin” photosensitizer is characterized.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gelfond, M.L.: Photodynamic therapy in oncology. Pract. Oncol. 8(4), 204–210 (2007)
Evtushenko, V.A., Vusik, M.V., Chizhikov, E.A.: Photodynamic therapy of skin relapse cancer with fotoditazin photosensitizer. Russ. Biother. J. 5(1), 25 (2006)
Gelfond, M.L., Barchuk, A.S., Vasilyev, D.V., Stukov, A.N.: Possibilities of photodynamic therapy in oncological practice. Russ. Biother. J. 2(4), 67–71 (2003)
Bakhmetyev, V.V., Sychov, M.M., Orlova, A.I., Potanina, E.A., Sovestnov, A.E.: Nanophosphors for photodynamic therapy of oncological diseases. Nanoindustry 8, 46–50 (2013)
Minakova, T.S., Sychov, M.M., Bakhmetyev, V.V., Eremina, N.S., Bogdanov, S.P., Zyatikov, I.A., Minakova, L.Yu.: The influence of Zn3(PO4)2: Mn – luminophores synthesis conditions on their surface and luminescent features. Adv. Mater. Res. 872, 106–111 (2014)
Malygin, V.V., Lebedev, L.A., Bakhmetyev, V.V., Keskinova, M.V., Sychov, M.M., Mjakin, S.V., Nakanishi, Y.: Synthesis and study of luminescent materials on the basis of mixed phosphates. Adv. Intell. Syst. Comput. 519, 47–54 (2016)
Bakhmetyev, V.V., Lebedev, L.A., Vlasenko, A.B., Bogdanov, S.P., Sovestnov, A.E., Minakova, T.S., Minakova, L.Yu., Sychov, M.M.: Luminescent materials on the basis of yttrium oxide and yttrium aluminum garnet used for photodynamic therapy. Key Eng. Mater. 670, 232–238 (2016)
Bakhmetyev, V.V., Minakova, T.S., Mjakin, S.V., Lebedev, L.A., Vlasenko, A.B., Nikandrova, A.A., Ekimova, I.A., Eremina, N.S., Sychov, M.M., Ringuede, A.: Synthesis and surface characterization of nanosized Y2O3: Eu and YAG: Eu luminescent phosphors which are useful for photodynamic therapy of cancer. Eur. J. Nanomed. 8(4), 173–184 (2016)
Wang, C., Cheng, X.: Hydrothermal synthesis and upconversion properties of α-NaYF4: Yb3+, Er3+ nanocrystals using citric acid as chelating ligand and NaNO3 as mineralizer. J. Nanosci. Nanotechnol. 15, 9656–9664 (2015)
Zeng, S., Tsang, M.-K., Chan, C.-F., Wong, K.-L., Hao, J.: Biomaterials 33(36), 9232–9238 (2012)
Ohyashiki, T., Nunomura, M., Katoh, T.: Detection of superoxide anion radical in phospholipid liposomal membrane by fluorescence quenching method using 1,3-diphenylisobenzofuran. Biochem. Biophys. Acta 1421, 131–139 (1999)
Wang, D.F., Zhang, X.D., Liu, Y.J., Wu, C.Y., Zhang, C.S., Wei, C.C., Zhao, Y.: Hydrothermal synthesis of hexagonal-phase NaYF4:Er, Yb with different shapes for application as photovoltaic up-converters. Chin. Phys. B. 22, 027801-1–027801-7 (2013)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Dorokhina, A.M., Bakhmetyev, V.V. (2019). Up-Conversion Nanosized Phosphors Based Fluoride for Photodynamic Therapy of Malignant Tumors. In: Laukaitis, G. (eds) Recent Advances in Technology Research and Education. INTER-ACADEMIA 2018. Lecture Notes in Networks and Systems, vol 53. Springer, Cham. https://doi.org/10.1007/978-3-319-99834-3_16
Download citation
DOI: https://doi.org/10.1007/978-3-319-99834-3_16
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-99833-6
Online ISBN: 978-3-319-99834-3
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)