Skip to main content

Thyroid Anatomy and Physiology

  • Chapter
  • First Online:
Book cover Advanced Practice in Endocrinology Nursing

Abstract

The term anatomy can be defined as the study of structure and form of an organism including its body parts, while physiology refers to the study of how these structures function and work.

This chapter outlines the anatomy of the thyroid gland, including the embryology and development, location, blood and nerve supply, and histology. It then details thyroid hormone physiology including thyroid hormone synthesis and secretion, transport and metabolism, and mechanism of action. It concludes with discussion of the thyroid hormone axis.

Relevant knowledge and understanding is fundamental to the understanding of thyroid disorders and key to underpinning care in clinical decision-making. Applying accurate knowledge of thyroid anatomy and physiology enables clinical practitioners to care, treat, and manage patients with thyroid disorders more effectively.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

T3:

Triiodothyronine

T4:

Thyroxine

TBG:

Thyroid-binding globulin

TPO:

Thyroperoxidase

TRH:

Thyrotropin-releasing hormone

TSH:

Thyroid-stimulating hormone

TTR:

Transthyretin

References

  • Benvenga S. Thyroid hormone transport proteins and the physiology of hormone binding. In: Braverman LE, Utiger RD, editors. The thyroid: fundamental and clinical text. 9th ed. Philadelphia: Lippincott Williams and Wilkins; 2005. p. 97.

    Google Scholar 

  • Bliss RD, Gauger PG, Delbridge LW. Surgeon’s approach to the thyroid gland: surgical anatomy and the importance of technique. World J Surg. 2000;24:891.

    Article  CAS  Google Scholar 

  • Braun EM, Windisch G, Wolf G, et al. The pyramidal lobe: clinical anatomy and its importance in thyroid surgery. Surg Radiol Anat. 2007;29:21.

    Article  Google Scholar 

  • Fawcett D, Jensh R. Bloom & Fawcett’s concise histology. New York: Arnold Publishers; 2002. p. 257–8. ISBN 0-340-80677-X.

    Google Scholar 

  • Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennstrom B, Samarut J. International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors. Pharmacol Rev. 2006;58(4):705–11.

    Article  CAS  Google Scholar 

  • Friesema EC, Ganguly S, Abdalla A, Manning Fox JE, Halestrap AP, Visser TJ. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J Biol Chem. 2003;278(41):40128–35.

    Article  CAS  Google Scholar 

  • Pankow BG, Michalak J, McGee MK. Adult human thyroid weight. Health Phys. 1985;49:1097.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bushra Ahmad .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Broughton, C., Ahmad, B. (2019). Thyroid Anatomy and Physiology. In: Llahana, S., Follin, C., Yedinak, C., Grossman, A. (eds) Advanced Practice in Endocrinology Nursing. Springer, Cham. https://doi.org/10.1007/978-3-319-99817-6_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-99817-6_26

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-99815-2

  • Online ISBN: 978-3-319-99817-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics