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Essentials of Interventional Cancer Pain Management pp 339–352Cite as

External Beam Radiotherapy in the Treatment of Painful Bone Metastases

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Abstract

The management of bone metastases is a multidisciplinary effort. External beam radiotherapy (EBRT) remains an effective and efficient method by which to palliate pain and prevent pathologic fracture. Various regimens have been utilized in the treatment of bone metastasis. The most commonly used and guideline-supported regimens range from 8 Gy in a single fraction to 30 Gy in 10 fractions. These regimens provide equivalent pain relief with minimal side effects. Stereotactic body radiation therapy (SBRT), a form of high-dose, highly conformal radiation therapy, shows promise in the treatment of selected patients. Due to the expense and complexity, the most appropriate indications for this technology are yet to be determined through continued accrual to ongoing clinical trials. National guidelines and quality metrics help define the use of EBRT in the treatment of uncomplicated bone metastasis.

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Authors and Affiliations

  1. Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA

    Candice Johnstone

  2. University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Houston, TX, USA

    Amol J. Ghia

  3. King Chulalongkorn Memorial Hospital and Chulalongkorn University, Department of Radiation Oncology, Bangkok, Thailand

    Anussara Prayongrat

Authors
  1. Candice Johnstone
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  2. Amol J. Ghia
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  3. Anussara Prayongrat
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Corresponding author

Correspondence to Candice Johnstone .

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Editors and Affiliations

  1. Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Amitabh Gulati

  2. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Vinay Puttanniah

  3. Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA

    Brian M. Bruel

  4. Midwest Neuroscience Institute, Center for the Relief of Pain, Kansas City, MO, USA

    William S. Rosenberg

  5. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Joseph C. Hung

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Johnstone, C., Ghia, A.J., Prayongrat, A. (2019). External Beam Radiotherapy in the Treatment of Painful Bone Metastases. In: Gulati, A., Puttanniah, V., Bruel, B., Rosenberg, W., Hung, J. (eds) Essentials of Interventional Cancer Pain Management. Springer, Cham. https://doi.org/10.1007/978-3-319-99684-4_38

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