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Essentials of Interventional Cancer Pain Management pp 273–276Cite as

Intrathecal Drug Delivery System Trialing for Cancer Pain Management

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Abstract

Intrathecal drug delivery systems (IDDS) play an important role in cancer pain management. Early placement of IDDS in cancer patients with moderate to severe pain can improve pain control, significantly decrease side effects, and even increase life expectancy (Smith TJ, Coyne PJ, Staats PS, et al., Ann Oncol 16:825–33, 2005; Smith TJ, Staats PS, Deer T, et al., J Clin Oncol 20:4040–9). Proper patient selection is an integral component to the ultimate success of implantation, and the final criteria in the selection process are often response to a trial. While IDDS trials play an important role for patients requiring long-term therapy, the necessity of a trial in cancer patients has been questioned as cancer pain and its treatments can differ from non-cancer pain in a variety of ways. There is currently no standardized trialing technique, and no method has been shown to be superior in predicting post-implantation outcomes.

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, Perioperative and Pain Medicine, The Pain Management Center at Brigham and Women’s Hospital, Chestnut Hill, MA, USA

    Namrata Khimani

  2. Department of Anesthesiology, Perioperative and Pain Medicine, The Pain Management Center at Brigham and Women’s Hospital, Harvard Medical School, Chestnut Hill, MA, USA

    Sanjeet Narang

Authors
  1. Namrata Khimani
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  2. Sanjeet Narang
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Editor information

Editors and Affiliations

  1. Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Amitabh Gulati

  2. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Vinay Puttanniah

  3. Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA

    Brian M. Bruel

  4. Midwest Neuroscience Institute, Center for the Relief of Pain, Kansas City, MO, USA

    William S. Rosenberg

  5. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Joseph C. Hung

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Khimani, N., Narang, S. (2019). Intrathecal Drug Delivery System Trialing for Cancer Pain Management. In: Gulati, A., Puttanniah, V., Bruel, B., Rosenberg, W., Hung, J. (eds) Essentials of Interventional Cancer Pain Management. Springer, Cham. https://doi.org/10.1007/978-3-319-99684-4_30

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  • DOI: https://doi.org/10.1007/978-3-319-99684-4_30

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-99682-0

  • Online ISBN: 978-3-319-99684-4

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