Abstract
Drug absorption is essential for a systemic medication to elicit its pharmacological response. The extent and rate of drug absorption have a direct impact on drug bioavailability. Here, we describe the key factors influencing drug absorption, the main mechanisms of drug absorption, and the most common models used to describe absorption kinetics. Examples and case studies are included.
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Further Reading
The reader is referred to the wonderful volume by Carsten Ehrhardt and Kwan-Jin Kim for additional insight on the absorption process with a focus on experimental and computational models of absorption (Drug Absorption Studies. In Situ, In Vitro and In Silico models, Springer, 2008). The Molecular Biopharmaceutics volume by Bente Steffansen et al. is also highly recommended to study experimental models of drug absorption (Molecular Biopharmaceutics, Pharmaceutical Press, 2010)
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Talevi, A., Bellera, C.L. (2018). Drug Absorption. In: Talevi, A., Quiroga, P. (eds) ADME Processes in Pharmaceutical Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-99593-9_2
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DOI: https://doi.org/10.1007/978-3-319-99593-9_2
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