Abstract
Biopharmaceutics and pharmacokinetics are pharmaceutical disciplines useful to improve the outcome of drug therapies, assist drug product development, and establish pharmacokinetics-pharmacodynamics models and in vitro-in vivo correlations. Here, we introduce some essential lexicon that will be used throughout this volume and discuss the relationship between drug exposure and pharmacological response, in the framework of the free drug theory/hypothesis.
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Further Reading
This introductory chapter has discussed some pharmacological concepts in a very brief and general manner. The reader is directed to pharmacology textbooks for a deeper insight into pharmacology basis. Chapter 4 of the volume Pharmacology: Principles and Practice (by Hacker et al, Elsevier, 2009) would be an excellent place to find more on ligand binding and tissue response
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Talevi, A., Quiroga, P.A.M. (2018). Introduction. Biopharmaceutics and Pharmacokinetics. In: Talevi, A., Quiroga, P. (eds) ADME Processes in Pharmaceutical Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-99593-9_1
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DOI: https://doi.org/10.1007/978-3-319-99593-9_1
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