Abstract
Nanoscience and Technology has emerged as a potentially promising field which encompasses physics, chemistry, biology, engineering science, medical science, material sciences, etc. This prodigal branch ensures production and manipulation of materials at the nanometer scale, thereby witnessing amazing applications in every field including biomedical sciences. The time and capital intensity along with potential annihilation to the environment led to the emergence of green protocols for the synthetic cues. It unfolded slowly and gained quantum popularity within a very short span of time. One can ensure synthesis of different metal/oxide with aptness and amenability for different applications. Health has been our prime concern since our inception on this planet and that might have compelled the human beings to peruse nature for remedies. Plants have always been our first choice for food, medicine, cloth, and shelter. It must have been quite exciting for our ancient harbingers to reckon plants as source of medicine and a therapeutic mean to alleviate ailments. Ayurveda—our ancient treasure of knowledge—is a wonderful source that delineates the interaction between metal salts and herb extracts, better known as Shodhan in ayurvedic cues, today better known as functional nanomaterials. Later on, we realized with time that plants have treasures of primary and secondary metabolites like flavonoids, alkaloids, steroids, poly phenols, saponins, tannins, and other compounds, which act as reducing and stabilizing agents for the bioreduction reaction to synthesized novel metal nanoparticles. So, our glorious ancient mythology has emerged as a prodigally promising technology. The green synthesized nanoparticles have effectively been used to control the various endemic diseases such as malaria, cancer, HIV, hepatitis, and other acute diseases. Recently, nanoparticles of silver and gold are found extremely useful for different applications such as in optoelectronic devices, ultrasensitive chemical sensor, biosensors, catalysts, separation sciences, drug delivery, DNA and RNA analysis, gene therapy, antimicrobial agent, etc. This chapter discusses the biosynthesis of metal nanoparticles using medicinal plant and/or plant parts, which enhance the medicinal values. Also, discussed the role of primary as well as secondary metabolites of different plant and/or plant parts in accomplishing the nanotransformation, bioreduction, and stabilization of nanoparticles.
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References
Ahmad A, Mukherjee P, Senapati S, Mandal D, Khan MI, Kumar R, Sastry M (2003) Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium oxysporum. Colloids Surf B Biointerfaces 28:313–318
Ahmed M, Hussain F (2013) Chemical composition and biochemical activity of Aloe vera (Aloe barbadensis miller) leaves. Int J Chem Biochem Sci 3:29–33
Ahmed S, Ahmad M, Swami BL, Ikram S (2016) A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise. J Adv Res 7:17–28
Ali DM, Thajuddin N, Jeganathan K, Gunasekaran M (2011) Plant extract mediated synthesis of silver and gold nanoparticles and its antibacterial activity against clinically isolated pathogens. Colloids Surf B Biointerfaces 85:360–365
Amarnath K, Kumar J, Reddy T, Mahesh V, Ayyappan SR, Nellore J (2012) Synthesis and characterization of chitosan and grape polyphenols stabilized palladium nanoparticles and their antibacterial activity. Colloids Surf B Biointerfaces 92:254–261
Amin M, Anwar F, Janjua MRSA, Iqbal MA, Rashid U (2012) Green synthesis of silver nanoparticles through reduction with Solanum xanthocarpum L. berry extract: characterization, antimicrobial and urease inhibitory activities against Helicobacter pylori. Int J Mol Sci 13:9923–9941
Aromal SA, Philip D (2012) Green synthesis of gold nanoparticles using Trigonella foenumgraecum and its size dependent catalytic activity. Spectrochim Acta A 97:1–5
Asharani PV, Mun GLK, Hande MP, Valiyaveettil S (2009) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–290
Azam A, Ahmed AS, Oves M, Khan MS, Habib SS, Memic A (2012) Antimicrobial activity of metal oxide nanoparticles against Gram-positive and Gram-negative bacteria: a comparative study. Int J Nanomed 2012:6003–6009
Aziz N, Fatma T, Varma A, Prasad R (2014) Biogenic synthesis of silver nanoparticles using Scenedesmus abundans and evaluation of their antibacterial activity. J Nanopart 2014:689419. https://doi.org/10.1155/2014/689419
Aziz N, Faraz M, Pandey R, Sakir M, Fatma T, Varma A, Barman I, Prasad R (2015) Facile algae-derived route to biogenic silver nanoparticles: synthesis, antibacterial and photocatalytic properties. Langmuir 31:11605–11612. https://doi.org/10.1021/acs.langmuir.5b03081
Aziz N, Pandey R, Barman I, Prasad R (2016) Leveraging the attributes of Mucor hiemalis-derived silver nanoparticles for a synergistic broad-spectrum antimicrobial platform. Front Microbiol 7:1984. https://doi.org/10.3389/fmicb.2016.01984
Azzazy HME, Mansour MMH, Samir TM, Franco R (2012) Gold nanoparticles in the clinical laboratory: principles of preparation and applications. Clin Chem Lab Med 50:193–209
Banerjee J, Narendhirakannan RT (2011) Biosynthesis of silver nanoparticles from Syzygium cumini (L.) seed extract and evaluation of their in vitro antioxidant activities. Dig J Nanomater Biostruct 6:961–968
Bankar A, Joshi B, Kumar AR, Zinjarde S (2010) Banana peel extract mediated novel route for the synthesis of silver nanoparticles. Colloids Surf A Physicochem Eng Asp 368:58–63
Bankura P, Maity D, Mollick MM, Mondal D, Bhowmick B, Bain MK, Chakraborty A, Sarkar J, Acharya K, Chattopadhyay D (2012) Synthesis, characterization and antimicrobial activity of dextran stabilized silver nanoparticles in aqueous medium. Carbohydr Polym 1:1159–1165
Bar H, Bhui DK, Sahoo GP, Sarkar P, De SP (2009) Green synthesis of silver nanoparticles using latex of Jatropha Curcas. Colloids Surf A Physicochem Eng Aspects 339:134–139
Barkalina N, Charalambous C, Jones C, Coward K (2014) Nanotechnology in reproductive medicine: emerging applications of nanomaterials. Nanomedicine 10(5):921–938
Baruwati B, Polshettiwar V, Varma RS (2009) Glutathione promoted expeditious green synthesis of silver nanoparticles in water using microwaves. Green Chem 11:926–930
Bhuyan T, Mishra K, Khanuja M, Prasad R, Varma A (2015) Biosynthesis of zinc oxide nanoparticles from Azadirachta indica for antibacterial and photocatalytic applications. Mater Sci Semicond Process 32:55–61
Bindhu MR, Umadevi M (2013) Synthesis of monodispersed silver nanoparticles using Hibiscus cannabinus leaf extract and its antimicrobial activity. Spectrochim Acta A Mol Biomol Spectrosc 101:184–190
Birla SS, Tiwari VV, Gade AK, Ingle AP, Yadav AP, Rai MK (2009) Fabrication of silver nanoparticles by Phoma glomerata and its combined effect against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Lett Appl Microbiol 1:2173–2179
Chandran SP, Chaudhary M, Pasricha R, Ahmad A, Sastry M (2006) Synthesis of gold nanotriangles and silver nanoparticles using Aloe vera plant extract. Biotechnol Prog 22:577–583
Cruz D, Fale PL, Mourato A, Vaz PD, Serralheiro ML, Lino ARL (2010) Preparation and physicochemical characterization of Ag nanoparticles biosynthesized by Lippia citriodora (Lemon Verbena). Colloids Surf B Biointerfaces 81:67–73
Daisy P, Saipriya K (2012) Biochemical analysis of Cassia fistula aqueous extracts and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus. Int J Nanomed 7:1189–1202
Daniel MC, Astruc D (2004) Gold nanoparticles: assembly, supramolecular chemistry, quantum size related properties, and applications toward biology, catalysis, and nanotechnology. Chem Rev 104:293–346
Das RK, Gogoi N, Bora U (2011) Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract. Bioprocess Biosyst Eng 34:615–619
Cormode DP, Skajaa T, Fayad ZA, Willem JMM (2009) Nanotechnology in medical imaging: probe design and applications. Arterioscler Thromb Vasc Biol 29:992–1000
Dipankar C, Murugan S (2012) The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts. Colloids Surf B Biointerfaces 98:112–119
Dubey SP, Lahtinen M, Sarkka H, Sillanpaa M (2010) Bioprospective of Sorbus aucuparia leaf extract in development of silver and gold nanocolloids. Colloids Surf B Biointerfaces 80:26–33
Dhuper S, Panda D, Nayak PL (2012) Green synthesis and characterization of zero valent iron nanoparticles from the leaf extract of Mangifera indica. Nano Trends: J Nanotech App 13:16–22
Du L, Jiang H, Liu X, Wang E (2007) Biosynthesis of gold nanoparticles assisted by Escherichia coli DH5α and its application on direct electrochemistry of hemoglobin. Electrochem Commun 9:1165–1170
Durán N, Marcato PD, De Souza GIH, Alves OL, Esposito E (2007) Antibacterial effect of silver nanoparticles produced by fungal process on textile fabrics and their effluent treatment. J Biomed Nanotechnol 3:203–208
El-Rafie MH, Mohamed AA, Shaheen TI, Hebeish A (2010) Antimicrobial effect of silver nanoparticles produced by fungal process on cotton fabrics. Carbohydr Polym 80:779–782
Fakruddin M, Hossain Z, Afroz H (2012) Prospects and applications of nanobiotechnology: a medical perspective. J Nanobiotechnol 10:1–8
Fatima F, Bajpai P, Pathak N, Singh S, Priya S, Verma SR (2015) Antimicrobial and immunomodulatory efficacy of extracellularly synthesized silver and gold nanoparticles by a novel phosphate solubilizing fungus Bipolaris tetramera. BMC Microbiol 15:52–61
Fayaz AM, Balaji K, Girilal M, Kalaichelvan PT, Venkatesan R (2009) Mycobased synthesis of silver nanoparticles and their incorporation into sodium alginate films for vegetable and fruit preservation. J Agric Food Chem 57:6246–6252
Flores CY, Miñán AG, Grillo CA, Salvarezza RC, Vericat C, Schilardi PL (2013) Citrate capped silver nanoparticles showing good bactericidal effect against both planktonic and sessile bacteria and a low cytotoxicity to osteoblastic cells. ACS Appl Mater Interfaces 5:3149–3159
Fortin D, Beveridge TJ (2000) From biology to biotechnology and medical applications. In: Aeuerien E (ed) Biomineralization. Weinheim, Wiley VCH
Fortina P, Kricka LJ, Graves DJ, Park J, Hyslop T, Tam F (2007) Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer. Trends Biotechnol 25:145–152
Gade A, Gaikwad S, Tiwari V, Yadav A, Ingle A, Rai M (2010) Biofabrication of silver nanoparticles by Opuntiaficus-indica: in vitro antibacterial activity and study of the mechanism involved in the synthesis. Curr Nanosci 6:370–375
Gan PP, Li SFY (2012) Potential of plant as a biological factory to synthesize gold and silver nanoparticles and their applications. Rev Environ Sci Biotechnol 11:169–206
Geethalakshmi R, Sarada DVL (2010) Synthesis of plant mediated silver nanoparticles using Trianthema decandra extract and evaluation of their antimicrobial activities. Int J Eng Sci Technol 2:970–975
Ghodake G, Lim SR, Lee DS (2013) Casein hydrolytic peptides mediated green synthesis of antibacterial silver nanoparticles. Colloids Surf B Biointerfaces 108:147–151
Ghosh S, Patil S, Ahire M, Kitture R, Kale S, Pardesi K, Cameotra SS, Bellare J, Dhavale DD, Jabgunde A, Chopad BA (2012) Synthesis of silver nanoparticles using Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents. Int J Nanomed 7:483–496
Gopinath V, MubarakAli D, Priyadarshini S, Priyadharsshini NM, Thajuddin N, Velusamy P (2012) Biosynthesis of silver nanoparticles from Tribulus terrestris and its antimicrobial activity a novel biological approach. Colloids Surf B Biointerfaces 96:69–74
Gordon T, Perlstein B, Houbara O, Felner I, Banin E, Margel S (2011) Synthesis and characterization of zinc/iron oxide composite nanoparticles and their antibacterial properties. Colloids Surf A Physicochem Eng Aspects 374:1–8
Guo D, Zhu L, Huang Z, Zhou H, Ge Y, Ma W, Wu J, Zhang X, Zhou X, Zhang Y (2013) Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions. Biomaterials 34:7884–7894
Han G, Ghosh P, Rotello VM (2007) Functionalized gold nanoparticles for drug delivery. Nanomedicine 2:113–123
Haverkamp RG, Marshall AT (2009) The mechanism of metal nanoparticle formation in plants: limits on accumulation. J Nanopart Res 11:1453–1463
Jha AK, Prasad K (2010) Green synthesis of silver nanoparticles using Cycas leaf. Int J Green Nanotechnol Phy Chem 1:110–117
Jha AK, Prasad K (2011a) Biosynthesis of gold nanoparticles using bael (Aegle marmelos) leaf: mythology meets technology. Int J Green Nanotechnol Phys Chem 3:92–97
Jha AK, Prasad K (2011b) Green fruit of chili (Capsicum annum L.) synthesizes nano silver. Dig J Nanomater Biostruct 6:1717–1723
Jha AK, Prasad K (2012) Biosynthesis of gold nanoparticles using common aromatic plants. Int J Green Nanotechnol Phy Chem 4:219–224
Jha AK, Prasad K (2013) Rose (Rosa sp.) petals assisted green synthesis of gold nanoparticles. J Bionanosci 7:1–6
Jha AK, Prasad K (2015) Facile green synthesis of metal and oxide nanoparticles using Papaya juice. J Bionanosci 9:311–314
Jha AK, Prasad K (2016a) Aquatic fern (Azolla Sp.) assisted synthesis of gold nanoparticles. Int J Nanosci 15:1650008–1650005
Jha AK, Prasad K (2016b) Green synthesis and antimicrobial activity of silver nanoparticles onto cotton fabric: an amenable option for textile industries. Adv Mater Lett 7:42–46
Jha AK, Prasad K, Kumar V, Prasad K (2009) Biosynthesis of silver nanoparticles using Eclipta leaf. Biotechnol Prog 25:1476–1479
Jha AK, Kumar V, Prasad K (2011) Biosynthesis of metal and oxide nanoparticles using orange juice. J Bionanosci 5:162–166
Jayaprakash A, Sangeetha R (2015) Phytochemical screening of Punica granatum Linn. peel extracts. J Acad Indust Res 4:160–162
Jain D, Daima HK, Kachhwaha S, Kothari SL (2009) Synthesis of plant-mediated silver nanoparticles using papaya fruit extract and evaluation of their anti-microbial activities. Dig J Nanomat Biostruct 4:557–563
Jayaseelan C, Rahuman AA, Rajakumar G, Kirthi AV, Santhoshkumar T, Marimuthu S (2011) Synthesis of pediculocidal and larvicidal silver nanoparticles by leaf extract from heart leaf moon seed plant Tinospora cordifolia Miers. Parasitol Res 109:185–194
Joerger R, Klaus T, Granqvist CG (2000) Biologically produced silver–carbon composite materials for optically functional thin-film coatings. Adv Mater 12:407–409
Joshi N, Jain N, Pathak A, Singh J, Prasad R, Upadhyaya CP (2018) Biosynthesis of silver nanoparticles using Carissa carandas berries and its potential antibacterial activities. J Sol-Gel Sci Techn 86(3):682–689. https://doi.org/10.1007/s10971-018-4666-2
Jacob SJP, Finub JS, Narayanan A (2012) Synthesis of silver nanoparticles using Piper longum leaf extracts and its cytotoxic activity against Hep-2 cell line. Colloids Surf B Biointerfaces 91:212–214
Jacob S, Finub J, Narayanan A (2011) Synthesis of silver nanoparticles using Piper longum leaf extracts and its cytotoxic activity against Hep-2 cell line. Colloids Surf B Biointerfaces 91:212–214
Kaviya S, Santhanalakshmi J, Viswanathan B, Muthumary J, Srinivasan K (2011) Biosynthesis of silver nanoparticles using Citrus sinensis peel extract and its antibacterial activity. Spectrochim Acta A 79:594–598
Khalil KA, Fouad H, Elsarnagawy T, Almajhdi FN (2013) Plant mediated green synthesis of silver nanoparticles—a review. Int J Electrochem Sci 8:3483–3493
Kim JS, Kuk E, Yu KN, Jong-Ho K, Park SJ, Lee HJ, Kim SH (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine 3:95–101
Kora AJ, Sashidhar RB, Arunachalam J (2012) Aqueous extract of gum olibanum (Boswellia serrata): a reductant and stabilizer for the biosynthesis of antibacterial silver nanoparticles. Process Biochem 47:1516–1520
Krishnan V, Bupesh G, Manikandan E, Thanigai AK, Magesh S (2016) Green synthesis of silver nanoparticles using Piper nigrum concoction and its anticancer activity against MCF-7 and Hep-2 cell lines. J Antimicrob Agents 2:123–128
Krishnaraj C, Jagan EG, Rajasekar S, Selvakumar P, Kalaichelvan PT, Mohan N (2010) Synthesis of silver nanoparticles using Acalypha indica leaf extracts and its antibacterial activity against water borne pathogens. Colloids Surf B Biointerfaces 76:50–56
Krolikowska A, Kudelski A, Michota A, Bukowska J (2003) SERS studies on the structure of thioglycolic acid monolayers on silver and gold. Surf Sci 532:227–232
Kumar DA, Palanichamy V, Roopan SM (2014) Green synthesis of silver nanoparticles using Alternanthera dentata leaf extract at room temperature and their antimicrobial activity. Spectrochim Acta A Mol Biomol Spectrosc 127:168–171
Kumari N, Kumari P, Jha AK, Prasad K (2018a) Enhanced antimicrobial activity in biosynthesized ZnO nanoparticles. AIP Conf Proc 1953:030054
Kumari P, Kumari N, Jha AK, Singh KP, Prasad K (2018b) Nyctanthes arbortristis mediated synthesis of silver nanoparticles: cytotoxicity assay against THP-1 human leukemia cell lines. AIP Conf Proc 1953:030071
Kumari N, Jha AK, Prasad K (2017) Fungal nanotechnology and biomedicine. In: Prasad R (ed) Fungal nanotechnology: applications in agriculture, industry, and medicine, Fungal biology. Springer. ISBN: 978-3-319-68423-9
Kuppusamy P, Yusoff MM, Maniam GP, Govindan N (2016) Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications—an updated report. Saudi Pharm J 24:473–484
Liu L, Yang J, Xie J, Luo Z, Jiang J, Yang Y (2013) The potent antimicrobial properties of cell penetrating peptide conjugated silver nanoparticles with excellent selectivity for Gram positive bacteria over erythrocytes. Nanoscale 5:3834–3840
Lokina S, Stephen A, Kaviyarasan V, Arulvasu C, Narayanan V (2015) Cytotoxicity and antimicrobial studies of silver nanoparticles synthesized using Psidium guajava L. extract. Synth React Inorg Met-Org Nano-Metal Chem 45:426–432
Maensiri S, Laokul P, Klinkaewnarong J, Phokha S, Promarak V, Seraphin S (2008) Indium oxide (In2O3) nanoparticles using Aloe vera plant extract: synthesis and optical properties. J Optoelectron Adv Mater 10:161–165
Majeed S, Danish M, Zahrudin AHB, Dash GK (2018) Biosynthesis and characterization of silver nanoparticles from fungal species and its antibacterial and anticancer effect. Karbala Int J Modern Sci 4:86–92
Majeed S, Abdullah MS, Nanda A, Ansari MT (2016) In vitro study of the antibacterial and anticancer activities of silver nanoparticles synthesized from Penicillium brevicompactum (MTCC-1999). J Taibah Univ Sci 10:614–620
Makarov VV, Love AJ, Sinitsyna OV, Makarova SS, Yaminsky IV, Taliansky ME, Kalinina NO (2014) “Green” nanotechnologies: synthesis of metal nanoparticles using plants. Acta Nat 6:35–44
Mallikarjuna K, Dillip GR, Narashima G, Sushma NJ, Raju BDP (2012) Phytofabrication and characterization of silver nanoparticles from Piper betel broth. Res J Nanosci Nanotech 2:17–23
Manikandan D, Prakash DG, Gandhi NN (2014) A rapid and green route to synthesis of silver nanoparticles from Plectranthus barbatus (coleus forskohlii) root extract for antimicrobial activity. Int J Chem Tech Res 6:4391–4396
Mittal AK, Chisti Y, Banerjee UC (2013) Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv 31:346–356
Mokhtari N, Daneshpajouh S, Seyedbagheri S, Atashdehghan R, Abdi K, Sarkar S, Minaian S, Shahverdi HR, Shahverdi AR (2009) Biological synthesis of very small silver nanoparticles by culture supernatant of Klebsiella pneumonia: the effects of visible light irradiation and the liquid mixing process. Mater Res Bull 44:1415–1421
Monda S, Roy N, Laskar RA, Sk I, Basu S, Mandal D, Begum NA (2011) Biogenic synthesis of Ag, Au and bimetallic Au/Ag alloy nanoparticles using aqueous extract of mahogany (Swietenia mahogani JACQ.) leaves. Colloids Surf B Biointerfaces 82:497–504
MubarakAli D, Thajuddin N, Jeganathan K, Gunasekaran M (2011) Plant extract mediated synthesis of silver and gold nanoparticles and its antibacterial activity against clinically isolated pathogens. Colloids Surf B Biointerfaces 85:360–365
Nagajyothi PC, Muthuraman P, Sreekanth TVM, Kim DH, Shim J (2017) Green synthesis: in-vitro anticancer activity of copper oxide nanoparticles against human cervical carcinoma cells. Arab J Chem 10:215–225
Nagati VB, Alwala J, Koyyati R, Donda MR, Banala R, Padigya PRM (2012) Green synthesis of plant-mediated silver nanoparticles using Withania somnifera leaf extract and evaluation of their anti-microbial activity. Asian Pac J Trop Biomed 2:1–5
Namratha N, Monica PV (2013) Green synthesis of silver nanoparticles using Mentha asiatica (Mint) extract and evaluation of their antimicrobial potential. J Pharm Tech 3:170–174
Nikalje AP (2015) Nanotechnology and its applications in medicine. Med Chem 5:081–089
Ninganagouda S, Rathod V, Singh D (2014) Characterization and biosynthesis of silver nanoparticles using a fungus Aspergillus niger. Int Lett Nat Sci 10:49–57
Niraimathi KL, Sudha V, Lavanya R, Brindha P (2012) Biosynthesis of silver nanoparticles using Alternanthera sessilis (Linn.) extract and their antimicrobial, antioxidant activities. Colloids Surf B Biointerfaces 88:34–39
Oliveira MM, Ugarte D, Zanchet D, Zarbin AJG (2005) Influence of synthetic parameters on the size, structure, and stability of dodecanethiol-stabilized silver nanoparticles. J Colloid Interface Sci 292:429–435
Panigrahi S, Kundu S, Ghosh S, Nath S, Pal T (2004) General method of synthesis for metal nanoparticles. J Nanopart Res 6:411–414
Phull AR, Abbas Q, Ali A, Raza H, Kim SJ, Zia M, Haq I (2016) Antioxidant, cytotoxic and antimicrobial activities of green synthesized silver nanoparticles from crude extract of Bergenia ciliate. Future J Pharm Sci 2:31–36
Popescu M, Velea A, Lorinczi A (2010) Biogenic production of nanoparticles. Dig J Nanomater Biostruct 5:1035–1040
Prabhu S, Poulose EK (2012) Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 2:32–41
Prasad KS, Pathak D, Patel A, Dalwadi P, Prasad R, Patel P, Kaliaperumal SK (2011) Biogenic synthesis of silver nanoparticles using Nicotiana tobaccum leaf extract and study of their antibacterial effect. Afr J Biotechnol 9(54):8122–8130
Prasad R (2014) Synthesis of silver nanoparticles in photosynthetic plants. J Nanopart 2014:963961. https://doi.org/10.1155/2014/963961
Prasad R, Bhattacharyya A, Nguyen QD (2017) Nanotechnology in sustainable agriculture: recent developments, challenges, and perspectives. Front Microbiol 8:1014. https://doi.org/10.3389/fmicb.2017.01014
Prasad R, Kumar V, Prasad KS (2014) Nanotechnology in sustainable agriculture: present concerns and future aspects. Afr J Biotechnol 13(6):705–713
Prasad R, Pandey R, Barman I (2016) Engineering tailored nanoparticles with microbes: quo vadis. WIREs Nanomed Nanobiotechnol 8:316–330. https://doi.org/10.1002/wnan.1363
Prasad R, Swamy VS (2013) Antibacterial activity of silver nanoparticles synthesized by bark extract of Syzygium cumini. J Nanopart 2013:431218. https://doi.org/10.1155/2013/431218
Prasad R, Swamy VS, Varma A (2012) Biogenic synthesis of silver nanoparticles from the leaf extract of Syzygium cumini (L.) and its antibacterial activity. Int J Pharm Bio Sci 3(4):745–752
Premanathan M, Karthikeyan K, Jeyasubramanian K, Manivannan G (2011) Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. Nanomedicine 7:184–192
Rai M, Ingle AP, Gupta IR, Birla SS, Yadav AP, Abd-Elsalam KA (2013) Potential role of biological systems in formation of nanoparticles: mechanism of synthesis and biomedical applications. Curr Nanosci 9:576–587
Rajeshkumar S (2016) Anticancer activity of eco-friendly gold nanoparticles against lung and liver cancer cells. J Genet Eng Biotechnol 14:195–202
Ramar M, Manikandan B, Marimuthu PN, Raman T, Mahalingam A, Subramanian P (2014) Synthesis of silver nanoparticles using Solanum trilobatum fruits extract and its antibacterial, cytotoxic activity against human breast cancer cell line MCF 7. Spectrochim Acta A 140:223–228
Rao KJ, Paria S (2013) Green synthesis of silver nanoparticles from aqueous Aegle marmelos leaf extract. Mater Res Bull 48:628–638
Ray S, Sarkar S, Kundu S (2011) Extracellular biosynthesis of silver nanoparticles using the mycorrhhizal mushroom Tricholoma crassum (BERK.) SACC: its antimicrobial activity against pathogenic bacteria and fungus, including multidrug resistant plant and human bacteria. Dig J Nanomater Biostruct 6:1289–1299
Roy S, Das TK (2015) Plant mediated green synthesis of silver nanoparticles—a review. Int J Plant Biol Res 3:1044–1055
Roy K, Sarkar CK, Ghosh CK (2015) Single-step novel biosynthesis of silver nanoparticles using Cucumis sativus fruit extract and study of its photcatalytic and antibacterial activity. Dig J Nanomater Biostruct 10:107–115
Safaepour M, Shahverdi AR, Shahverdi HR, Khorramizadeh MR, Gohari AR (2009) Green synthesis of small silver nanoparticles using geraniol and its cytotoxicity against Fibrosarcoma–Wehi 164. Avicenna J Med Biotechnol 1:111–115
Salem W, Leitner DR, Zingl FG, Schratter G, Prassl R, Goessler W, Reidl J, Schild S (2015) Antibacterial activity of silver and zinc nanoparticles against Vibrio cholerae and enterotoxic Escherichia coli. Int J Med Microbiol 305:85–95
Sanpui P, Chattopadhyay A, Ghosh SS (2011) Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier. ACS Appl Mater Interfaces 3:218–228
Sathishkumar M, Sneha K, Won SW, Cho CW, Kim S, Yun YS (2009) Cinnamomum zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its bactericidal activity. Colloids Surf B Biointerfaces 73:332–338
Satyavani K, Gurudeeban S, Ramanathan T, Balasubramanian T (2011) Biomedical potential of silver nanoparticles synthesized from calli cells of Citrullus colocynthis (L.) Schrad. J Nanobiotechnol 9:43–51
Saxena A, Tripathi RM, Singh RP (2010) Biological synthesis of silver nanoparticles by using onion (Allium cepa) extract and their antibacterial activity. Dig J Nanomater Biostruct 5:427–432
Shameli K, Ahmad M, Al-Mulla EAJ, Ibrahim NA, Shabanzadeh P, Rustaiyan A, Abdollahi Y (2012) Green biosynthesis of silver nanoparticles using Callicarpa maingayi stem bark extraction. Molecules 17:8506–8517
Sharma G, Sharma AR, Kurian M, Bhavesh R, Nam JS, Lee SS (2014) Green synthesis of silver nanoparticle using Myristica fragrans (nutmeg) seed extract and its biological activity. Dig J Nanomater Biostruct 9:325–332
Singh M, Singh S, Prasad S, Gambhir IS (2008) Nanotechnology in medicine and antibacterial effect of silver nanoparticles. Dig J Nanomater Biostruct 3:115–122
Singh S, Saikia JP, Buragohain AK (2013) A novel “Green” synthesis of colloidal silver nanoparticles (SNP) using Dillenia indica fruit extract. Colloids Surf B Biointerfaces 102:83–85
Singhal G, Bhavesh R, Kasariya K, Sharma AR, Singh RP (2011) Biosynthesis of silver nanoparticles using Ocimum sanctum (Tulsi) leaf extract and screening its antimicrobial activity. J Nanopart Res 13:2981–2988
Sinha S, Pan I, Chanda P, Sen SK (2009) Nanoparticles fabrication using ambient biological resources. J Appl Biosci 19:1113–1130
Sondi I, Salopek-Sondi B (2004) Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. J Colloid Interface Sci 275:177–182
Song JY, Kim BS (2009) Biological synthesis of bimetallic Au/Ag nanoparticles using Persimmon (Diospyros kaki) leaf extract. Korean J Chem Eng 25:808–811
Subramanian V (2012) Green synthesis of silver nanoparticles using Coleus amboinicus lour, antioxitant activity and invitro cytotoxicity against Ehrlich’s Ascite carcinoma. J Pharm Res 5:1268–1272
Sukirtha R, Priyanka KM, Antony JJ, Kamalakkannan S, Thangam R, Gunasekaran P, Krishnan M, Achiraman S (2012) Cytotoxic effect of Green synthesized silver nanoparticles using Melia azedarach against in vitro HeLa cell lines and lymphoma mice mode. Process Biochem 47:273–279
Surendiran A, Sandhiya S, Pradhan SC, Adithan C (2009) Novel applications of nanotechnology in medicine. Indian J Med Res 130:689–701
Suriyakalaa U, Antony JJ, Suganya S, Siva D, Sukirtha R, Kamalakkannan S, Pichiah PBT, Achiraman S (2013) Hepatocurative activity of biosynthesized silver nanoparticles fabricated using Andrographis paniculata. Colloids Surf B Biointerfaces 102:189–194
Swamy VS, Prasad R (2012) Green synthesis of silver nanoparticles from the leaf extract of Santalum album and its antimicrobial activity. J Optoelectron Adv M 4(3):53–59
Tripathy A, Raichur AM, Chandrasekaran N, Prathna TC, Mukherjee A (2010) Process variables in biomimetic synthesis of silver nanoparticles by aqueous extract of Azadirachta indica (Neem) leaves. J Nanopart Res 12:237–241
Tripathi AK, Harsh NSK, Gupta N (2007) Fungal treatment of industrial effluents: a mini review. Life Sci J 4:78–81
Umoren SA, Obot IB, Gasem ZM (2014) Green synthesis and characterization of silver nanoparticles using red apple (Malus domestica) fruit extract at room temperature. J Mater Environ Sci 5:907–914
Valtchev V, Tosheva L (2013) Porous nanosized particles: preparation, properties, and applications. Chem Rev 113:6734–6760
Vanaja M, Rajeshkumar S, Paulkumar K, Gnanajobitha G, Malarkodi C, Annadurai G (2013) Phytosynthesis and characterization of silver nanoparticles using stem extract of Coleus aromaticus. Int J Mater Biomat Appl 3:1–4
Vankar PS, Bajpai D (2010) Preparation of gold nanoparticles from Mirabilis jalapa flowers. Indian J Biochem Biophys 47:157–160
Verma VC, Kharwar RN, Gange AC (2010) Biosynthesis of antimicrobial silver nanoparticles by the endophytic fungus Aspergillus clavatus. Nanomedicine 5:33–40
Vivek R, Thangam R, Muthuchelian K, Gunasekaran P, Kaveri K, Kannan S (2012) Green biosynthesis of silver nanoparticles from Annona squamosa leaf extract and its in vitro cytotoxic effect on MCF-7 cells. Process Biochem 47:2405–2410
Wang X, Zuo J, Keil P, Grundmeier G (2007) Comparing the growth of PVD silver nanoparticles on ultra-thin fluorocarbon plasma polymer films and self-assembled fluoroalkyl silane monolayers. Nanotechnology 18:265303
Weiss J, Takhistov P, Julianmcclements D (2006) Functional materials in food nanotechnology. J Food Sci 71:107–116
Zahir AA, Rahuman AA (2012) Evaluation of different extracts and synthesized silver nanoparticles from leaves of Euphorbia prostrate against the plant Haemaphysalis bispinosa and Hippobosca maculate. Vet Parasitol 187:511–520
Zhang H, Smith JA, Oyanedel-Craver V (2012) The effect of natural water conditions on the anti-bacterial performance and stability of silver nanoparticles capped with different polymers. Water Resour 46:691–699
Zhang S, Tang Y, Vlahovic B (2016) A review on preparation and applications of silver-containing nanofibers. Nanoscale Res Lett 11:1–8
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Kumari, P., Kumari, N., Jha, A.K., Singh, K.P., Prasad, K. (2018). Synthesis of Functionalized Nanoparticles for Biomedical Applications. In: Prasad, R., Jha, A., Prasad, K. (eds) Exploring the Realms of Nature for Nanosynthesis. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-99570-0_9
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