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Benign Tumors and Tumor-Like Conditions

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Mediastinal Pathology

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Abstract

The tumors that this chapter on benign tumors and tumor-like conditions encompasses represent a diverse group of lesions that do not necessarily have much in common as a group. Thus, the lesions will be grouped in many cases by the gross appearance and presentation, and when possible by the main histopathological features. Needless to say, the lesions for the most part are unusual tumors in the mediastinal compartment, and in some instances only a few cases have been described in the literature. In order to facilitate their study, this chapter will discuss three separate types of tumors, which have been separated into three main categories: cystic tumors, solid tumors and tumor-like conditions, and histiocytic tumors. These include: cystic tumors (foregut cysts: bronchogenic cyst, esophageal cyst, enteric cyst; mesothelial cysts: pericardial cyst, pleural cyst; thymic cyst: unilocular, multilocular), solid tumors and tumor-like conditions (sclerosing/fibrosing mediastinitis, thymic hyperplasia, adenomatoid tumor, glomus tumor, cholesteroloma, pecoma, sclerosing hemangioma), and histiocytic tumors (Langerhans cell histiocytosis, Rosai-Dorfman disease). This chapter will be presented from the practical point of view for the practicing pathologist who may be called upon to interpret these tumors. Clinical, pathological, histopathological, immunohistochemical, radiological, gross, molecular features will be discussed, as well as differential diagnoses and staging.

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  1. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Neda Kalhor & Cesar Moran

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  1. Neda Kalhor
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  2. Cesar Moran
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Correspondence to Neda Kalhor .

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Kalhor, N., Moran, C. (2019). Benign Tumors and Tumor-Like Conditions. In: Mediastinal Pathology . Springer, Cham. https://doi.org/10.1007/978-3-319-98980-8_4

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