Abstract
Gastric cancer is one of the leading causes of cancer mortality worldwide, although its incidence in the USA is lower compared to Southeast Asia. Its presentation can be incidental, with nonspecific abdominal pain as the most common presenting symptom. For the work-up of gastric cancer, novel diagnostic modalities have emerged. Endoscopic ultrasound and positron emission tomography with the combination of computed tomography, together with diagnostic laparoscopy and peritoneal cytology, make the clinical staging and preoperative planning very accurate. However, surgery, in combination with chemotherapy or chemoradiation, is still the only modality that can offer a chance for a cure. Currently, multidisciplinary approach is essential for improved outcomes.
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References
Park SR, Lee JS, Kim CG, Kim HK, Kook MC, Kim YW, et al. Endoscopic ultrasound and computed tomography in restaging and predicting prognosis after neoadjuvant chemotherapy in patients with locally advanced gastric cancer. Cancer. 2008;112(11):2368–76.
Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, Sullivan DC, Jessup JM, Brierley JD, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR, editors. AJCC Cancer staging manual. 8th ed. Chicago: Springer; 2017. p. 1032.
Sarela AI, Lefkowitz R, Brennan MF, Karpeh MS. Selection of patients with gastric adenocarcinoma for laparoscopic staging. Am J Surg. 2006;191(1):134–8.
Mezhir JJ, Shah MA, Jacks LM, Brennan MF, Coit DG, Strong VE. Positive peritoneal cytology in patients with gastric cancer: natural history and outcome of 291 patients. Ann Surg Oncol. 2010;17(12):3173–80.
Cunningham D, Allum WH, Stenning SP, Thompson JN, Van de Velde CJ, Nicolson M, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med. 2006;355(1):11–20.
Smalley SR, Benedetti JK, Haller DG, Hundahl SA, Estes NC, Ajani JA, et al. Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection. J Clin Oncol. 2012;30(19):2327–33.
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Wolchok, C.L., Georgakis, G.V. (2019). Management of Gastric Cancer. In: Docimo Jr., S., Pauli, E. (eds) Clinical Algorithms in General Surgery . Springer, Cham. https://doi.org/10.1007/978-3-319-98497-1_43
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DOI: https://doi.org/10.1007/978-3-319-98497-1_43
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