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Germ Cell Tumors

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Central Nervous System Intraoperative Cytopathology

Part of the book series: Essentials in Cytopathology ((EICP,volume 13))

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Abstract

CNS germ cell tumors (GCTs) are uncommon neoplasms affecting primarily children and young adults. These tumors most often arise in the midline involving the pineal and suprasellar regions, but involvement of multiple tumor sites around the third ventricle is not uncommon. Histologically, CNS GCTs represent a wide array of diseases but can be divided into two highly prognostic groups: pure germinomas and non-germinomatous or “malignant” germ cell tumors, with teratomas often considered as a separate category. Because of their different biological behavior, different prognosis, and their different therapeutic possibilities, it is advisable to differentiate among these three groups during intraoperative consultation.

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Authors and Affiliations

  1. Professor of Pathology, Complutense University School of Medicine, Madrid, Spain

    César R. Lacruz

  2. Professor of Pathology, University Hospital Extremadura, Medical School, Badajoz, Spain

    Javier Saénz de Santamaría

  3. Pathologist, Director Ultrasound-guided Fine Needle Aspiration Service, Outpatient Pathology Associates / Precision Pathology, Sacramento, CA, USA

    Ricardo H. Bardales

Authors
  1. César R. Lacruz
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  2. Javier Saénz de Santamaría
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  3. Ricardo H. Bardales
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Lacruz, C.R., Saénz de Santamaría, J., Bardales, R.H. (2018). Germ Cell Tumors. In: Central Nervous System Intraoperative Cytopathology. Essentials in Cytopathology, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-319-98491-9_15

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  • DOI: https://doi.org/10.1007/978-3-319-98491-9_15

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98490-2

  • Online ISBN: 978-3-319-98491-9

  • eBook Packages: MedicineMedicine (R0)

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