Abstract
Even in the current age of advanced neuroimaging and image-guided biopsies, intraoperative consultation is essential for evaluating CNS lesions and providing firm grounds for decision making and guide surgical approach. Likewise, intraoperative consultation is necessary to avoid non-diagnostic biopsies by confirming that the specimen obtained is adequate for an accurate final diagnosis. Intraoperative cytology is a rapid diagnostic modality with >90% diagnostic accuracy. This chapter reviews this topic and also includes a historical overview of the squash/smear technique and a summary of the 2016 updated WHO classification of the CNS tumors.
Nothing can be a greater value to a neurosurgeon than the ability to visualize, immediately, from the gross appearances of a tumor what will be its histological nature. Too great emphasis cannot be laid on this.
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Lacruz, C.R., Saénz de Santamaría, J., Bardales, R.H. (2018). Introduction to CNS Intraoperative Cytopathology. In: Central Nervous System Intraoperative Cytopathology. Essentials in Cytopathology, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-319-98491-9_1
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