Abstract
Skin ulcers are a very frequent complication of systemic sclerosis (SSc) that affect almost half of the patients, either with limited or diffuse subset of the disease. About 75% of the affected patients have their first DU episode within 5 years from their first non-Raynaud symptom. Disabling pain in patients with skin ulcers is a common concern and challenge for healthcare providers. Considerable advances have been made in the understanding of pain mechanisms with resultant new and innovative techniques to reduce discomfort and suffering. Comprehensive management and pain control are critical for these patients to improve outcomes and speed healing.
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Galluccio F, Matucci-Cerinic M. Registry evaluation of digital ulcers in systemic sclerosis. Int J Rheumatol. 2010;2010. pii: 363679
Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, et al. Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions. Rheumatology (Oxford). 2010;49(7):1374–82.
Korn JH. Scleroderma: a treatable disease. Cleve Clin J Med. 2003;70(11):954, 956, 958 passim.
Barbul A. Wound healing. In: Bruncardi CF, Anderson DK, Billiar TR, Dunn DL, Pollack RE, editors. Schwartz’s principles of surgery. 8th ed. New York: McGraw-Hill; 2005.
Merkel PA, Herlyn K, Martin RW, Anderson JJ, et al. Measuring disease activity and functional status in patients with scleroderma and Raynaud’s phenomenon. Arthritis Rheum. 2002;46(9):2410–20.
Mouthon L, Mestre-Stanislas C, Bérezné A, Rannou F, et al. Impact of digital ulcers on disability and health-related quality of life in systemic sclerosis. Ann Rheum Dis. 2010;69(1):214–7.
Newland PK, Wipke-Tevis DD, Williams DA, et al. Impact of pain on outcomes in long-term care residents with and without multiple sclerosis. J Am Geriatr Soc. 2005;53:1490–6.
Aaron LA, Patterson DR, Finch CP, et al. The utility of a burn specific measure of pain anxiety to prospectively predict pain and function: a comparative analysis. Burns. 2001;27:329–34.
Pediani R. What has pain relief to do with acute surgical wound healing? World Wide Wounds. http://www.worldwidewounds.com/2001/march/Pediani/Pain relief-surgical wounds.html. Accessed 01 April 2010.
Popescu A, Salcido RS. Wound pain: a challenge for the patient and wound care specialist. Adv Skin Wound Care. 2004;17(1):14–20.
Vileikyte L. Stress and wound healing. Clin Dermatol. 2007;25(1):49–55.
Fleck CA. Managing wound pain: today and in the future. Adv Skin Wound Care. 2007;20(3):138–45.
Sussman C, Bates-Jenson C. Wound care. In: A collaborative practice manual for health professionals. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 278–81.
Richeimer S. The Richeimer pain update (Richeimer Pain Medical Group), www.helpforpain.com/arch2000dec.htm.
Melzak R, Wall PD. Pain mechanisms: a new theory. Science. 1965;150:971–9.
Hunt S, Koltzenburg M. The neurobiology of pain: (molecular and cellular neurobiology). Oxford: Oxford University Press; 2005.
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Galluccio, F. (2019). Pain. In: Matucci-Cerinic, M., Denton, C. (eds) Atlas of Ulcers in Systemic Sclerosis. Springer, Cham. https://doi.org/10.1007/978-3-319-98477-3_12
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DOI: https://doi.org/10.1007/978-3-319-98477-3_12
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