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Mathematical Modeling of Protein Complexes pp 309–363Cite as

Mathematical Algorithms for Finding the Optimal Composition of the Amino Acid Composition of Peptides Used as a Therapy

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Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

In this chapter, two algorithms have been developed, one of which (Algorithm 3) was developed specifically for the selection of amino acid residues in peptides to improve their affinity in the interaction of peptides with full-length proteins, and Algorithm 4 was developed to search for “scattered” active region of the protein when bound to the peptide.

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Authors and Affiliations

  1. Saint Petersburg State University, Saint Petersburg, Russia

    Tatiana Koshlan

  2. Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, Russia

    Kirill Kulikov

Authors
  1. Tatiana Koshlan
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  2. Kirill Kulikov
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Correspondence to Kirill Kulikov .

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Koshlan, T., Kulikov, K. (2018). Mathematical Algorithms for Finding the Optimal Composition of the Amino Acid Composition of Peptides Used as a Therapy. In: Mathematical Modeling of Protein Complexes. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-98304-2_8

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