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Precision Medicine

  • Arthur AndréEmail author
  • Jean-Jacques Vignaux
Chapter
Part of the Health Informatics book series (HI)

Abstract

Modelizing biology and life has always been a challenge to the modern scientific method due to the complexity of the components and interactions of a biological organization from the cell to a whole human body. Information technology (IT) offers the ability to treat and organize large amounts of data and leads to a paradigm of integration—in opposition to reduction—to explain biological systems and phenomenon. Quantitative datasets of DNA, RNA, proteins, and metabolites provide an unprecedented starting point to understand the effects of perturbations on a cell and, with addition of clinical tests and imaging, the effect on the whole body. The informational view of biology defines biological information—biomarker—as a given data integrated in a network. This leads to a “systems” approach to physiology and pathophysiology.

Keywords

4P medicine Precision medicine Omics IT 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de ParisParisFrance
  2. 2.Sorbonne UniversitéParisFrance
  3. 3.iTechCare Medical Data Research, OsteopathParisFrance

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