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Precision Medicine

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Digital Medicine

Part of the book series: Health Informatics ((HI))

Abstract

Modelizing biology and life has always been a challenge to the modern scientific method due to the complexity of the components and interactions of a biological organization from the cell to a whole human body. Information technology (IT) offers the ability to treat and organize large amounts of data and leads to a paradigm of integration—in opposition to reduction—to explain biological systems and phenomenon. Quantitative datasets of DNA, RNA, proteins, and metabolites provide an unprecedented starting point to understand the effects of perturbations on a cell and, with addition of clinical tests and imaging, the effect on the whole body. The informational view of biology defines biological information—biomarker—as a given data integrated in a network. This leads to a “systems” approach to physiology and pathophysiology.

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Author information

Authors and Affiliations

  1. Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France

    Arthur André

  2. Sorbonne Université, Paris, France

    Arthur André

  3. iTechCare Medical Data Research, Osteopath, Paris, France

    Jean-Jacques Vignaux

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  1. Arthur André
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  2. Jean-Jacques Vignaux
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Correspondence to Arthur André .

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  1. Pitié-Salpêtrière Hospital, Paris, France

    Arthur André

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André, A., Vignaux, JJ. (2019). Precision Medicine. In: André, A. (eds) Digital Medicine. Health Informatics. Springer, Cham. https://doi.org/10.1007/978-3-319-98216-8_5

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  • DOI: https://doi.org/10.1007/978-3-319-98216-8_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98215-1

  • Online ISBN: 978-3-319-98216-8

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