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Neonatal Lupus

  • Tor Shwayder
  • Samantha L. Schneider
  • Devika Icecreamwala
  • Marla N. Jahnke
Chapter
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Abstract

Neonatal lupus erythematosus (NLE) falls into the category of subacute cutaneous lupus erythematosus (SCLE). It presents at birth in infants whose mothers have a diagnosis of systemic lupus erythematosus (SLE) in approximately 1 in 20,000 births [1]. Diagnostically, patients have a positive anti-Ro/SSA antibody as this antibody was obtained from the mother through transplacental passage [1]. If a mother has had one child affected, there is an ~25% chance of having another affected infant [1].

References

  1. 1.
    Shiiya C, Ota M. Facial rash, fever, and anemia in a newborn. JAMA. 2017;317(20):2125–6.CrossRefGoogle Scholar
  2. 2.
    Lee LA, Frank MB, McCubbin VR, Reichlin M. Autoantibodies of neonatal lupus erythematosus. J Investig Dermatol. 1994;102(6):963–6.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Tor Shwayder
    • 1
  • Samantha L. Schneider
    • 2
  • Devika Icecreamwala
    • 3
  • Marla N. Jahnke
    • 2
  1. 1.Pediatric DermatologyHenry Ford HospitalDetroitUSA
  2. 2.Department of DermatologyHenry Ford HospitalDetroitUSA
  3. 3.Icecreamwala DermatologyBerkeleyUSA

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