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Neonatal lupus erythematosus (NLE) falls into the category of subacute cutaneous lupus erythematosus (SCLE). It presents at birth in infants whose mothers have a diagnosis of systemic lupus erythematosus (SLE) in approximately 1 in 20,000 births . Diagnostically, patients have a positive anti-Ro/SSA antibody as this antibody was obtained from the mother through transplacental passage . If a mother has had one child affected, there is an ~25% chance of having another affected infant .