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Epidermolytic ichthyosis (EI) is an example of a non-syndromic inherited ichthyosiform condition with a varied clinical appearance. Other names for the condition include bullous congenital ichthyosiform erythroderma, epidermolytic hyperkeratosis and bullous ichthyosis . This is a rare condition with a worldwide prevalence of 1 in 200,000 to 300,000 . It is transmitted as an autosomal dominant disorder with complete penetration. The most common mutations occur in two keratin genes: KRT1 or KRT10 [1, 2].