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Epidermolytic Ichthyosis

  • Tor Shwayder
  • Samantha L. Schneider
  • Devika Icecreamwala
  • Marla N. Jahnke
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Abstract

Epidermolytic ichthyosis (EI) is an example of a non-syndromic inherited ichthyosiform condition with a varied clinical appearance. Other names for the condition include bullous congenital ichthyosiform erythroderma, epidermolytic hyperkeratosis and bullous ichthyosis [1]. This is a rare condition with a worldwide prevalence of 1 in 200,000 to 300,000 [1]. It is transmitted as an autosomal dominant disorder with complete penetration. The most common mutations occur in two keratin genes: KRT1 or KRT10 [1, 2].

References

  1. 1.
    Vahlquist A, Fischer J, Torma H. Inherited nonsyndromic ichthyoses: an update on pathophysiology, diagnosis and treatment. Am J Clin Dermatol. 2018;19(1):51–66; PMID: 28815464.CrossRefGoogle Scholar
  2. 2.
    Takeichi T, Akiyama M. Inherited ichthyosis: non-syndromic forms. J Dermatol. 2016;43(3):242–51.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Tor Shwayder
    • 1
  • Samantha L. Schneider
    • 2
  • Devika Icecreamwala
    • 3
  • Marla N. Jahnke
    • 2
  1. 1.Pediatric DermatologyHenry Ford HospitalDetroitUSA
  2. 2.Department of DermatologyHenry Ford HospitalDetroitUSA
  3. 3.Icecreamwala DermatologyBerkeleyUSA

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