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Dystrophic Epidermolysis Bullosa

  • Tor Shwayder
  • Samantha L. Schneider
  • Devika Icecreamwala
  • Marla N. Jahnke
Chapter
  • 285 Downloads

Abstract

Dystrophic epidermolysis bullosa (DEB) is the most severe presentation of epidermolysis bullosa with skin fragility occurring in the sublamina densa region. DEB is the second most common presentation of EB after EBS. There are two subtypes of DEB. The first is the dominant dystrophic phenotype (DDEB) and the second is the recessive dystrophic phenotype (RDEB). Both subtypes have mutations in COL7A1, which correlates to type VII collagen.

References

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Tor Shwayder
    • 1
  • Samantha L. Schneider
    • 2
  • Devika Icecreamwala
    • 3
  • Marla N. Jahnke
    • 2
  1. 1.Pediatric DermatologyHenry Ford HospitalDetroitUSA
  2. 2.Department of DermatologyHenry Ford HospitalDetroitUSA
  3. 3.Icecreamwala DermatologyBerkeleyUSA

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