Abstract
Keratoconus (KC) is a noninflammatory progressive corneal ectasia. It is characterized by the irregular astigmatism produced by both central and peripheral corneal stromal thinning. It is a relatively common pathology of unknown etiology. Many patients with mild or moderate KC can improve their best-corrected visual acuity (BCVA) by wearing glasses or hard contact lenses. Keratoplasty is indicated in advanced KC cases when the vision does not improve after optical correction or when there is corneal scarring that alters the transparency of the cornea.
Penetrating keratoplasty (PK) has been the gold-standard surgery for the treatment of advanced KC for many years. This procedure involves replacing the normal endothelium in young patients, which is normal in the vast majority of cases. In recent years, deep anterior lamellar keratoplasty (DALK) has proven to be an excellent alternative to PK for patients with KC. DALK provides visual outcomes comparable to those achieved with PK and it has the advantage of preserving the patient’s endothelium and thus reducing the rejection rate. In this chapter we want to explain DALK surgical technique and its advantages and disadvantages.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Bahar I, Kaiserman I, Srinivasan S, et al. Comparison of three different techniques of corneal transplantation for keratoconus. Am J Ophthalmol. 2008;146:905–12.
Felipe AF, Hammersmith KM, Nottage JM, et al. Indications, visual outcome, and ectasia in clear corneal transplants 20 years old or more. Cornea. 2013;32(5):602–7.
Zadok D, Schwarts S, Marcovich A, et al. Penetrating keratoplasty for keratoconus: long term results. Cornea. 2005;24:959–61.
Colin J, Velou S. Current surgical options for keratoconus. J Cataract Refract Surg. 2003;29(2):379–86.
Espandar L, Meyer J. Keratoconus: overview and update on treatment. Middle East Afr J Ophthalmol. 2010;17(1):15–20.
Carlson AN. Keratoconus. Ophthalmology. 2009;116(10):2036–7. author reply 2037–8.
Yüksel B, Kandemir B, Uzunel UD, et al. Comparison of visual and topographic outcomes of deep-anterior lamellar keratoplasty and penetrating keratoplasty in keratoconus. Int J Ophthalmol. 2017;10(3):385–90.
Tan DT, Dart JK, Holland EJ, et al. Corneal transplantation. Lancet. 2012;379(9827):1749–61.
Cohen AW, Goins KM, Sutphin JE, et al. Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus. Int Ophthalmol. 2010;30(6):675–81.
Feizi S, Javadi MA, Rezaei KM. Recurrent keratoconus in a corneal graft after deep anterior lamellar keratoplasty. J Ophthalmic Vis Res. 2012;7(4):328–31.
Arenas E, Esquenazi S, Anwar M, et al. Lamellar corneal transplantation. Surv Ophthalmol. 2012;57(6):510–29.
Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998;42(4):297–319.
Faraj LA, Hashmani K, Khatib T, et al. The changing face of corneal graft rejection. Br J Ophthalmol. 2012;96(8):1049–50.
Van den Biggelaar FJ, Cheng YY, Nuijts RM, et al. Economic evaluation of deep anterior lamellar keratoplasty versus penetrating keratoplasty in the Netherlands. Am J Ophthalmol. 2011;151(3):449–59.
Sugita J, Kondo J. Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement. Br J Ophthalmol. 1997;81(3):184–8.
Sogutlu Sari E, Kubaloglu A, Unal M, et al. Deep anterior lamellar keratoplasty versus penetrating keratoplasty for macular corneal dystrophy: a randomized trial. Am J Ophthalmol. 2013;156:267–74.
Borderie VM, Sandali O, Bullet J, et al. Long-term results of deep anterior lamellar versus penetrating keratoplasty. Ophthalmology. 2012;119(2):249–55.
Salouti R, Masoumpour M, Nowroozzadeh MH, et al. Changes in corneal endothelial cell profile measurements after deep anterior lamellar keratoplasty for keratoconus. Cornea. 2013;32(6):751–6.
Sogutlu Sari E, Kubaloglu A, Unal M, et al. Penetrating keratoplasty versus deep anterior lamellar keratoplasty: comparison of optical and visual quality outcomes. Br J Ophthalmol. 2012;96(8):1063–7.
Chen G, Tzekov R, Li W, et al. Deep anterior lamellar keratoplasty versus penetrating keratoplasty: a meta-analysis of randomized controlled trials. Cornea. 2016;35(2):169–74.
Amayem AF, Hamdi IM, Hamdi MM. Refractive and visual outcomes of penetrating keratoplasty versus deep anterior lamellar keratoplasty with hydrodissection for treatment of keratoconus. Cornea. 2013;32(4):e2–5.
Javadi MA, Feizi S, Yazdani S, et al. Deep anterior lamellar keratoplasty versus penetrating keratoplasty for keratoconus: a clinical trial. Cornea. 2010;29(4):365–71.
Sarnicola E, Sarnicola C, Sarnicola V. Deep anterior lamellar keratoplasty: surgical technique, indications, clinical, results and complications. In: Güell JL, editor. Cornea. ESASO course series, vol. 6. Basel: Karger; 2015. p. 81–101.
Abdelkader A, Kaufan HE. Descemetic versus pre-descemetic lamellar keratoplasty: clinical and confocal study. Cornea. 2011;30(11):1244–52.
Koytak A, Kubaloglu A, Sari ES, et al. Changes in central macular thickness after uncomplicated corneal transplantation for keratoconus: penetrating keratoplasty versus deep anterior lamellar keratoplasty. Cornea. 2011;30(12):1318–21.
Shimmura S, Ando M, Ishioka M, et al. Same size donor corneas for myopic keratoconus. Cornea. 2004;23(4):345–9.
Güell JL, Aristizábal-Montes D. Viscobubble technique for deep anterior lamellar keratoplasty. J Emmetropia. 2014;5:65–8.
Rabinowitz YS. Ectatic disorders of the cornea. In: Foster CF, Azar DT, Dohlman CH, editors. The cornea: scientific foundations and clinical practice. Philadelphia: Lipincott Williams & Wilkins; 2005. p. 889–911.
Maguire LJ. Ectatic corneal degenerations. In: Kauffman HE, Barron BA, McDonald MB, editors. The cornea. Boston: Butterworth-Heinemann; 1998. p. 525–37.
Bergmanson JP, Goosey JD, Patel CK, et al. Recurrence or re-emergence of keratoconus what is the evidence telling us? Literature review and two case reports. Ocul Surf. 2014;12(4):267–72.
Koenig SB. Bilateral recurrent self-induced keratoconus. Eye Contact Lens. 2008;34(6):343–4.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Eguiza, V.S. et al. (2019). Why Perform Deep Anterior Lamelar Keratoplasty and Not Full-Thickness Keratoplasty for the Treatment of Keratoconus. In: Barbara, A. (eds) Controversies in the Management of Keratoconus . Springer, Cham. https://doi.org/10.1007/978-3-319-98032-4_25
Download citation
DOI: https://doi.org/10.1007/978-3-319-98032-4_25
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-98031-7
Online ISBN: 978-3-319-98032-4
eBook Packages: MedicineMedicine (R0)