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Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization (ETV–CPC) Versus CSF Shunting

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Cerebrospinal Fluid Disorders

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Abstract

Choroid plexus removal and cautery was described a century ago, but went out of vogue due to its technical difficulty and associated morbidity. From the 1950s to 2000s, cerebrospinal fluid shunts and endoscopic third ventriculostomy (ETV) remained the mainstay of treatment for pediatric hydrocephalus, including infants. In the 2000s, Warf’s innovative development of the modern ETV with choroid plexus cauterization (CPC) technique and robust scientific study in the unique setting of the CURE Children’s Hospital of Uganda brought a renaissance of choroid plexus obliteration as a safe and effective treatment option. This chapter recounts the history of choroid plexus surgery, explains its biologic and pathophysiologic basis, describes the operative technique and outcome of ETV+CPC in the global setting, and compares it with other conventional treatments.

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Authors and Affiliations

  1. Division of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    William B. Lo & Abhaya V. Kulkarni

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  1. William B. Lo
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  2. Abhaya V. Kulkarni
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Correspondence to Abhaya V. Kulkarni .

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Editors and Affiliations

  1. Department of Neurological Surgery, Washington University School of Medicine, St. Louis Children’s Hospital, St. Louis, MO, USA

    David D. Limbrick Jr.

  2. Nationwide Children’s Hospital, Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, OH, USA

    Jeffrey R. Leonard

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Lo, W.B., Kulkarni, A.V. (2019). Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization (ETV–CPC) Versus CSF Shunting. In: Limbrick Jr., D., Leonard, J. (eds) Cerebrospinal Fluid Disorders . Springer, Cham. https://doi.org/10.1007/978-3-319-97928-1_18

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  • DOI: https://doi.org/10.1007/978-3-319-97928-1_18

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