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Treatment of Drenching Sweats in Parkinson’s Disease

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Part of the book series: Current Clinical Neurology ((CCNEU))

Abstract

Abnormal sweating is a sometimes distressing autonomic feature that relates to abnormal reflex vasodilation in skin. It occurs in 10–30% of Parkinson’s Disease patients and is possibly more common in younger women. Altered sweating appears to occur in two forms: that related to dopaminergic innervation (“off” sweating) and the other being non-dopaminergic. As sweat glands are stimulated by sympathetic cholinergic, adrenergic, and noradrenergic pathways, these represent the major non-dopaminergic types. Treatment options are limited. In some cases no treatment is needed. For the dopaminergic type, treating “off” times is the best strategy. For non-dopaminergic type the use of anticholinergics can be helpful.

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Correspondence to Stewart A. Factor DO .

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Factor, S.A. (2019). Treatment of Drenching Sweats in Parkinson’s Disease. In: Reich, S., Factor, S. (eds) Therapy of Movement Disorders. Current Clinical Neurology. Humana, Cham. https://doi.org/10.1007/978-3-319-97897-0_15

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  • DOI: https://doi.org/10.1007/978-3-319-97897-0_15

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-319-97896-3

  • Online ISBN: 978-3-319-97897-0

  • eBook Packages: MedicineMedicine (R0)

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