Surface Enhanced IR Absorption and Raman Detection of Tryptophan Amino Acids Over Silver Nanoislands Deposited on Graphene

  • Preeti GargEmail author
  • Praveen Sahoo
  • R. Raman
  • R. K. Soni
Conference paper
Part of the Springer Proceedings in Physics book series (SPPHY, volume 215)


Surface enhanced IR absorption (SEIRA) and Surface enhanced Raman scattering (SERS) of amino acids in protein (L-Tryptophan) drop coated on deposited silver nanoislands over monolayer of graphene on silicon were obtained using FTIR in reflectance mode and micro-Raman respectively. In this work, two dimensional Ag nanoislands were prepared on LPCVD-grown monolayer graphene on Si. Here we describe the enhanced interaction between light and silver nanoislands deposited on graphene as a tool for trace detection of molecular entities, especially in the area of bio-molecule detection and characterisation. This enhanced interaction is due to localised surface plasmons generated in silver nano islands that we fabricate by simple means of metal deposition on top of graphene. We have achieved femto molar detection limit of L-Tryptophan on monolayer graphene.


Bio-Sensing Graphene SERS SEIRA L-Tryptophan 



The authors would like to thank the Director of the Solid State Physics Laboratory (SSPL) for giving permission to publish this work.


  1. 1.
    L.M. Malard, M.A. Pimenta, G. Dresselhaus, M.S. Dresselhaus, Raman spectroscopy in graphene. Phys. Rep. 473, 51–87 (2009)ADSCrossRefGoogle Scholar
  2. 2.
    A.K. Geim, K.S. Novoselov, The rise of graphene. Nat. Mater. 6, 183–191 (2007)ADSCrossRefGoogle Scholar
  3. 3.
    E.C. Le Ru, E. Blackie, M. Meyer, Surface enhanced raman scattering enhancement factors: a comprehensive study. J. Phys. Chem. C 111, 113794–113803 (2007)Google Scholar
  4. 4.
    M. Fleischm, P.J. Hendra, A.J. McQuilla, Raman Spectra of pyridine absorbed at a silver electrode. Chem. Phys. Lett. 26(2), 163–166 (1974)ADSCrossRefGoogle Scholar
  5. 5.
    A.X. Wang, Review of recent progress of plasmonic materials and nano-structure for surface-enhanced Raman scattering materials. Materials 8, 3024–3305 (2015)ADSCrossRefGoogle Scholar
  6. 6.
    J. Theiss, P. Pavaskar, P.M. Echternach, R.E. Muller, S.B. Cronin, Plasmonic nanoparticle arrays with nanometer separation for high-performance SERS substrates. Nano Lett. 10(8), 2749–2754 (2010)ADSCrossRefGoogle Scholar
  7. 7.
    A. Urich, A. Pospischil, M.M. Furchi, D. Daitze, K. Unterrainer, T. Mueller, Silver nanoisland enhanced Raman interaction in graphene. Appl. Phys. Lett. 101, 153113 (2012)ADSCrossRefGoogle Scholar
  8. 8.
    A.C. Ferrari, D.M. Bosko, Raman Spectroscopy as a versatile tool for studying properties of graphene. Nat. Nanotechnol. 8, 235 (2013)ADSCrossRefGoogle Scholar
  9. 9.
    J. Lee, K.S. Novoselov, H.S. Shin, Interaction between metal and graphene: dependence on number of layer of graphene. ACS Nano 05, 608–612 (2011)CrossRefGoogle Scholar
  10. 10.
    M.K. Hossain, Y. Ozaki, Surface enhanced Raman Scattering; facts and inline trends. Curr. Sci. 97, 192–201 (2009)Google Scholar
  11. 11.
    H.R. Stuart, D.G. Hall, Island size effects in nano particle-enhanced photodetectors. Appl. Phys. Lett. 73, 3815 (1998)ADSCrossRefGoogle Scholar
  12. 12.
    E.C. Ru, E. Blackie, M. Meyer, P.G. Etchegoin, Surface enhanced Raman Scattering enhancement factors: a comprehensive study. J. Phys. Chem. C 111(37), 13794–13803 (2007)CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Preeti Garg
    • 1
    • 2
    Email author
  • Praveen Sahoo
    • 1
  • R. Raman
    • 1
  • R. K. Soni
    • 2
  1. 1.Solid State Physics LaboratoryTimarpurIndia
  2. 2.Indian Institute of TechnologyHauzkhasIndia

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