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Impedimetric Method to Monitor Biological Layer Formation on Central Venous Catheters for Hemodialysis Made of Carbothane

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Book cover Biomechanics in Medicine and Biology (BIOMECHANICS 2018)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 831))

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Abstract

The aim of the study was to specify by an impedimetric method the changes observed on the inner wall of central venous catheters for hemodialysis leading to the formation of a biological film. To evaluate these changes a patient-dialyzer model was built in which experimental parameters were kept closely similar to the clinical conditions of hemodialysis. The impedance spectra and SEM/EDS analysis of the biological layer deposited on the inner surface of the distal part of the catheter gave an insight into the structure of film formation and its chemical composition. Since an early detection of biofilm formation inside the distal part of the catheter is crucial for the safety of medical treatment and it usually prompts the implementation of antibiotic therapy. Developed impedimetric method can minimize the risk of infection and ensure the continuity of treatment.

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References

  1. Chan, M.R.: Hemodialysis central venous catheter dysfunction. Semin. Dial. 21, 516–521 (2008). https://doi.org/10.1111/j.1525-139X.2008.00495.x

    Article  Google Scholar 

  2. Saxena, A.K., Panhotra, B.R.: Haemodialysis catheter-related bloodstream infections: current treatment options and strategies for prevention. Swiss Med. Wkly. 127–138 (2005)

    Google Scholar 

  3. Venturini, E., Becuzzi, L., Magni, L.: Catheter-induced thrpmbosis of the superior vena cava. Vasc. Med. 1–4 (2012). https://doi.org/10.1155/2012/469619

    Article  Google Scholar 

  4. O’Grady, N.P., Alexander, M., Burns, L.A., Dellinger, E.P., Garland, J., Heard, S.O.: Guidelines for the prevention of intravascular catheter-related infections. Clin. Infect. Dis. 52, 1087–1099 (2011). https://doi.org/10.1093/cid/cir257

    Article  Google Scholar 

  5. Tsukashita, M., Anda, A., Balsam, L.: Type A aortic dissection: a rare complication of central venous catheter placement. J. Card. Surg. 29, 368–370 (2014)

    Article  Google Scholar 

  6. Deliberato, R.O., Marra, A.R., Correa, T.D., Martino, M.D.V., Correa, L., Pavao dos Santos, O.F., Edmond, M.B.: Catheter related bloodstream infection (CR-BSI) in ICU Patients: making the decision to remove or not to remove the central venous catheter. PLoS OnE 7, 3 (2012). https://doi.org/10.1371/journal.pone.0032687

    Article  Google Scholar 

  7. Raad, I., Hanna, H., Maki, D.: Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lan. Infect. Dis. 7, 645–657 (2007)

    Article  Google Scholar 

  8. Vascular Access Work Group. Clinical practice guidelines for vascular access. Am. J. Kidney Dis. 176–273 (2006). https://doi.org/10.1053/j.ajkd.2006.04.029

  9. Menglin, T., Mei, F., Lijun, C., Jinmei, Z., Peng, K., Shuhua, L.: Closed blood conservation device for reducing catheter-related infections in children after cardiac surgery. Crit. Care Nurse 5, 53–61 (2014)

    Google Scholar 

  10. Horvath, R., Collignon, P.: Controlling intravascular catheter infections. Aust. Prescr. 26, 41–43 (2003)

    Article  Google Scholar 

  11. Elliott, T.S.J.: The pathogensis and prevention of intervascular catheter infections Central Venous Catheters. Lancet Infect. Dis. 206-215 (2009)

    Google Scholar 

  12. Cornelis van Rooden, J., Schippers, E.F., Rosendaal, F.R., Meinders, A.E., Huisman, M.V.: Infectious complications of central venous catheters increase the risk of catheter-related thrombosis in hematology patients: a prospective study. J. Clin. Oncol. 23, 2655–2660 (2005). https://doi.org/10.1200/JCO.2005.05.002

    Article  Google Scholar 

  13. Davenport, A., Ahmand, J.: Medical management of hepatorenal syndrome. Nephrol. Dial. Transplant. 1, 34–41 (2012). https://doi.org/10.1093/ndt/gfr736

    Article  Google Scholar 

  14. Gahlot, R., Nigam, C., Kumar, V., Yadav, G., Anupurba, S.: Symposium: current concepts in critical care. Int. J. Crit. Illn. Inj. Sci. 4, 162–167 (2014). https://doi.org/10.4103/2229-5151.134184

    Article  Google Scholar 

  15. Maczynska, B., Przondo-Mordarska, A.: Bloodstream infections related to venous access. Zakazenia, p. 4 (2011)

    Google Scholar 

  16. Mozaffari, K., Bakhshandeh, H., Khalaj, H., Soudi H.: Incidence of catheter-related infections in hospitalized cardiovascular patients. Res. Cardiovasc. Med. 2, 99–103 (2013). https://doi.org/10.5812/cardiovascmed.9388

    Article  Google Scholar 

  17. Kutner, D.J.: Thrombotic complications of centra venous catheters in cancer patients. Oncologist 9, 207–216 (2004)

    Article  Google Scholar 

  18. Krishnasami, Z., Ton, D.C., Bimbo, L., Taylor, M.E., Balkovetz, D.F., Barker, J., Allon, M.: Management of hemodialysis catheter-related bacteremia with an adjunctive antibiotic lock solution. Kidney Int. 61, 1136–1142 (2002). https://doi.org/10.1046/j.1523-1755.2002.00201.x

    Article  Google Scholar 

  19. Paredes, J., Alonso-Arce, M., Sedano, B., Legarda, J., Arizti, F., Gómez, E., Aguinaga, A., Del Pozo, J.L., Arana, S.: Smart central venous port for early detection of bacterial biofilm related infections. Biomed. Microdevices 16, 365–374 (2014). https://doi.org/10.1007/s10544-014-9839-3

    Article  Google Scholar 

  20. Kingdon, E.J., et al.: Atrial thrombus and central venous dialysis catheters. Am. J. Kidney Dis. 38, 631–639 (2001)

    Article  Google Scholar 

  21. Dua, R., James, K.N., Trerotola, S.: Significance of echocardiographically detected tip thrombus associated with central venous catheters. J. Vasc. Interv. Radiol. 313 (2013). https://doi.org/10.1016/j.jvir.2013.01.338

    Article  Google Scholar 

  22. Paredes, J., Becerro, S., Arizti, F., Aguinaga, A., Del Pozo, J.L., Arana, S.: Real time monitoring of the impedance characteristics of Staphylococcal bacterial biofilm cultures with a modified CDC reactor system. Biosens. Bioelectron. 38, 226–232 (2012)

    Article  Google Scholar 

  23. Paredes, J., Becerro, S., Arizti, F., Aguinaga, A., Del Pozo, J.L., Arana, S.: Interdigitated microelectrode biosensor for bacterial biofilm growth monitoring by impedance spectroscopy technique in 96-well microtiter plates. Sensor Actuator 178, 663–670 (2013). https://doi.org/10.1016/j.snb.2013.01.027

    Article  Google Scholar 

  24. Ben-Yoav, H., Freeman, A., Sternheim, M., Shacham-Diamand, Y.: An electrochemical impedance model for integrated bacterial biofilms. Electrochim. Acta 56, 7780–7786 (2011). https://doi.org/10.1016/j.electacta.2010.12.025

    Article  Google Scholar 

  25. Taeyoung, K., Junil, K., Lee, J.H., Jeyong, Y.: Influence of attached bacteria and biofilm on double-layer capacitance during biofilm monitoring by electrochemicalimpedance spectroscopy. Wat. Res. 45, 4615–4622 (2011). https://doi.org/10.1016/j.watres.2011.06.010

    Article  Google Scholar 

  26. Wei, H., Ding, D., Wei, S., Guo, Z.: Anticorrosive conductive polyurethane multiwalled carbon nanotube nanocomposites. J. Mater. Chem. 45, 10805–10813 (2013)

    Article  Google Scholar 

  27. Ookubo, A., Nishida, M., Ooi, K., Ishida, K., Hashimura, Y., Ikawa, A., Yoshimura, Y., Kawada, J.: Mechanism of phosphate adsorption to a three-dimensional structure of boehmite in the presence of bovine serum albumin. J. Pharm. Sci. 82, 744–749 (1993)

    Article  Google Scholar 

  28. Wang, X., Herting, G., Wallindera, I., Blomberg, E.: Adsorption of bovine serum albumin on silver surfaces enhances the release of silver at pH neutral conditions. Phys. Chem. 17, 18524–18534 (2015). https://doi.org/10.1039/c5cp02306h

    Article  Google Scholar 

  29. Moradi, M., Yeganeh, H., Pazokifard, S.: Synthesis and assessment of novel anticorrosive polyurethane coatings containing an amine-functionalized nanoclay additive prepared by the cathodic electrophoretic deposition method. RSC Adv. 6, 28089–28102 (2016). https://doi.org/10.1039/C5RA26609B

    Article  Google Scholar 

  30. Mohsen, Q., SFadl-allah, S.A., El-Shenawy, N.S.: Electrochemical impedance spectroscopy study of the adsorption behavior of bovine serum albumin at biomimetic calcium - phosphate coating. Int. J. Electrochem. Sc. 7, 4510–4527 (2012)

    Google Scholar 

  31. Vlasova, I., Saletsky, A.: Study of the denaturation of human serum albumin by sodium dodecyl sulfate using the intrinsic fluorescence of albumin. J. App. Spectrosc. 76, 536–541 (2009)

    Article  Google Scholar 

  32. Hanamura, K., Tojo, A., Kinugasa, S.: The resistive index is a marker of renal function, pathology, prognosis, and responsiveness to steroid therapy in chronic kidney disease patients. Int. J. Nephrol. 1-9 (2012). https://doi.org/10.1155/2012/139565

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Biomedical Engineering Division, University of Zielona Gora, Licealna 9 Street, 65-547, Zielona Gora, Poland

    Ewa Paradowska, Marta Nycz, Katarzyna Arkusz & Elżbieta Krasicka-Cydzik

  2. Department of Intensive Care, Zielona Gora University Hospital, Zyty 6 Street, 65-046, Zielona Gora, Poland

    Bartosz Kudliński

Authors
  1. Ewa Paradowska
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  2. Marta Nycz
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  3. Katarzyna Arkusz
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  4. Bartosz Kudliński
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  5. Elżbieta Krasicka-Cydzik
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Corresponding author

Correspondence to Ewa Paradowska .

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Editors and Affiliations

  1. Division of Biomedical Engineering, Department of Mechanical Engineering, University of Zielona Góra, Zielona Góra, Poland

    Katarzyna Arkusz

  2. Division of Biomedical Engineering, Department of Mechanical Engineering, University of Zielona Góra, Zielona Góra, Poland

    Romuald Będziński

  3. Division of Biomedical Engineering, Department of Mechanical Engineering, University of Zielona Góra, Zielona Góra, Poland

    Tomasz Klekiel

  4. Division of Biocybernetics and Biomedical Engineering, Department of Mechanical Engineering, Bialystok University of Technology, Białystok, Poland

    Szczepan Piszczatowski

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Paradowska, E., Nycz, M., Arkusz, K., Kudliński, B., Krasicka-Cydzik, E. (2019). Impedimetric Method to Monitor Biological Layer Formation on Central Venous Catheters for Hemodialysis Made of Carbothane. In: Arkusz, K., Będziński, R., Klekiel, T., Piszczatowski, S. (eds) Biomechanics in Medicine and Biology. BIOMECHANICS 2018. Advances in Intelligent Systems and Computing, vol 831. Springer, Cham. https://doi.org/10.1007/978-3-319-97286-2_4

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