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Rapidly Progressive Glomerulonephritis

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Adolescents with Chronic Kidney Disease

Abstract

Rapidly progressive glomerulonephritis is rare in children and adolescents and is seen predominantly in the context of immune complex-mediated diseases. Children often present with non-specific signs and symptoms and may deteriorate rapidly, with the development of alveolar hemorrhage. Since early diagnosis and treatment are critical in improving outcomes, the care of these children should be performed by multidisciplinary teams that have the requisite experience. Serologic testing and renal biopsy are critical to guide therapy; however, therapy should not wait for diagnostic confirmation due to risk of disease progression. While the mortality associated with rapidly progressive glomerulonephritis has declined, outcomes remain suboptimal.

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Authors and Affiliations

  1. Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA, USA

    Lavjay Butani

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  1. Lavjay Butani
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Correspondence to Lavjay Butani .

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Editors and Affiliations

  1. Department of Pediatric Nephrology, UC Davis Medical Center, Sacramento, CA, USA

    Maha N. Haddad

  2. Department of Pediatrics, Division of Nephrology, University of California San Francisco, San Francisco, CA, USA

    Erica Winnicki

  3. Department of Pediatrics, UC Davis Children’s Hospital, Sacramento, CA, USA

    Stephanie Nguyen

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Butani, L. (2019). Rapidly Progressive Glomerulonephritis. In: Haddad, M., Winnicki, E., Nguyen, S. (eds) Adolescents with Chronic Kidney Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-97220-6_6

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  • DOI: https://doi.org/10.1007/978-3-319-97220-6_6

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