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Biotechnological Applications of Plant Proteolytic Enzymes pp 69–106Cite as

Peptide Synthesis Using Proteases as Catalyst

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Abstract

Proteolytic enzymes (proteases) comprise a group of hydrolases (EC 3.4, NC-IUBMB) which share the common feature of acting on peptide bonds. Proteases are among the best-studied enzymes in terms of structure–function relationship (Krowarsch et al. 2005). Proteases, by catalyzing the cleavage of other proteins and even themselves, have an enormous physiological significance, their coding genes representing as much as 2% of the total human genome (Schilling and Overall 2008).

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Authors and Affiliations

  1. Laboratorio de Bromatología, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, San Luis, Argentina

    Sonia Barberis, Mauricio Adaro, Anabella Origone & Grisel Bersi

  2. INFAP – CCT San Luis – CONICET, San Luis, Argentina

    Sonia Barberis, Mauricio Adaro, Anabella Origone & Grisel Bersi

  3. Laboratorio de Péptidos, Núcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

    Fanny Guzmán

  4. Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

    Andrés Illanes

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  1. Biological Research Institute, University of Mar del Plata, Mar del Plata, Argentina

    María Gabriela Guevara

  2. Biological Research Institute, University of Mar del Plata, Mar del Plata, Argentina

    Gustavo Raúl Daleo

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Barberis, S., Adaro, M., Origone, A., Bersi, G., Guzmán, F., Illanes, A. (2018). Peptide Synthesis Using Proteases as Catalyst. In: Guevara, M., Daleo, G. (eds) Biotechnological Applications of Plant Proteolytic Enzymes. Springer, Cham. https://doi.org/10.1007/978-3-319-97132-2_4

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