Abstract
This chapter discusses the barrier function of the placenta. It discusses how the placental decreases fetal drug exposure.
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Keywords
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The placenta is an imperfect barrier (allows many substances to cross)
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Cytochrome P-450 isoenzymes are located in the placenta, and some may be inducible
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These enzymes may metabolize agents and decrease fetal exposure
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Placenta may also bind substances to minimize fetal exposure to and accumulation of substances
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© 2019 Springer Nature Switzerland AG
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Wasson, C., Kelly, A., Ninan, D., Tran, Q. (2019). Barrier Function. In: Absolute Obstetric Anesthesia Review. Springer, Cham. https://doi.org/10.1007/978-3-319-96980-0_11
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DOI: https://doi.org/10.1007/978-3-319-96980-0_11
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Publisher Name: Springer, Cham
Print ISBN: 978-3-319-96979-4
Online ISBN: 978-3-319-96980-0
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