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Prognostic and Predictive Factors

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Breast Cancer

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Abstract

A variety of pathological parameters are used to assess prognosis and predict therapeutic response for breast cancer patients. These parameters include tumor size, axillary lymph node status, histological features, hormone receptor status, HER2 status and the proliferative capacity of the tumor. Several gene expression profiling assays have been developed in an attempt to predict the survival and response to therapies of breast cancer patients. These assays are based on the identification of prognostic gene signatures by using microarrays. Many groups have attempted to develop genomic tests based on genomic profiling to improve the prediction of clinical outcome compared with standard pathological and clinical markers.

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Authors and Affiliations

  1. Tuzlali Private Pathology Laboratory, Istanbul, Turkey

    Sitki Tuzlali

  2. Istanbul University, Istanbul Medical Faculty, Department of Pathology, Istanbul, Turkey

    Sitki Tuzlali & Ekrem Yavuz

Authors
  1. Sitki Tuzlali
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  2. Ekrem Yavuz
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Correspondence to Ekrem Yavuz .

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Editors and Affiliations

  1. Internal Medicine, Medical Oncology, Istanbul Medical Faculty, Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. General Surgery, Istanbul Medical Faculty, Department of Surgery, Istanbul University, Istanbul, Turkey

    Abdullah Igci

  3. Surgical Oncology, Magee-Women’s Hospital, University of Pittsburgh Medical Centre, Pittsburgh, PA, USA

    Atilla Soran

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Tuzlali, S., Yavuz, E. (2019). Prognostic and Predictive Factors. In: Aydiner, A., Igci, A., Soran, A. (eds) Breast Cancer . Springer, Cham. https://doi.org/10.1007/978-3-319-96947-3_6

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  • DOI: https://doi.org/10.1007/978-3-319-96947-3_6

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