Practicing Pathology in the Post-genomic Era: Challenges and Opportunities

  • Karen L. KaulEmail author


The rapid implementation of new molecular methods in support of precision medicine has been both exciting and challenging to pathology. Next-generation sequencing is coming to maturity as a clinical procedure, with concomitant development of guidelines for assay validation and performance, quality standards, and proficiency programs. Evolving issues include the type, target, and timing of genomic analysis of tumors and regulatory and reimbursement issues. Additionally, educational needs for pathology trainees, practicing pathologists, and clinical colleagues should be addressed.


Genomics Anatomic pathology Next-generation sequencing Molecular pathology Informatics pipeline Quality control Education Regulation Reimbursement 


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© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory Medicine, NorthShore University HealthSystemClinical Professor of Pathology, University of Chicago Pritzker School of MedicineEvanstonUSA

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