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Listing for Transplantation; Postoperative Management and Long-Term Follow-Up

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Book cover Pediatric Hepatology and Liver Transplantation

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Abstract

Pediatric liver transplantation (LT) differs widely from adult liver transplantation. A pediatric team experienced in LT is central to the care of these patients both pre- and post-LT. Centers of reference with a multidisciplinary team especially trained in LT improve patient outcomes. A standardized protocol is the foundation of successful short-term and long-term management of LT recipients. Nonetheless, protocols should be adapted to the individual needs of patients. In this chapter, a practical approach to pretransplant, transplant, and posttransplant care will be provided. Recommendations for pretransplant assessment, listing for transplant, and management during the pretransplant period are described in the first section. The second part will focus on a practical approach of early postoperative management and complications together with suggested diagnostic and therapeutic protocols. A suggested long-term follow-up schedule and complications surveillance will be provided in the third part of the chapter. These protocols are designed to be as comprehensive as possible and should be adapted to local resources.

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Abbreviations

AIH:

Autoimmune hepatitis

AILD:

Autoimmune liver disease

BA:

Biliary atresia

CNI:

Calcineurin inhibitor

DSA:

Donor-specific antibodies

FFP:

Fresh frozen plasma

HB:

Hepatoblastoma

HCC:

Hepatocarcinoma

HPS:

Hepatopulmonary syndrome

IS:

Immunosuppressive drugs

LT:

Liver transplantation

PH:

Portal hypertension

POPH:

Portopulmonary hypertension

PPI:

Proton-pump inhibitor

UCDA:

Ursodeoxycholic acid

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Authors and Affiliations

  1. Pediatric Gastroenterology, Hepatology and Nutrition Unit, Department of Pediatrics, Swiss Pediatric Liver Center, University Hospitals of Geneva, Geneva, Switzerland

    Nathalie Marie Rock & Valérie Anne McLin

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  1. Nathalie Marie Rock
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  2. Valérie Anne McLin
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Correspondence to Nathalie Marie Rock or Valérie Anne McLin .

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  1. Paediatric Hepatology, Gastroenterology and Transplantation, Hospital Papa Giovanni XXIII Bergamo, Bergamo, Italy

    Lorenzo D'Antiga

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Rock, N.M., McLin, V.A. (2019). Listing for Transplantation; Postoperative Management and Long-Term Follow-Up. In: D'Antiga, L. (eds) Pediatric Hepatology and Liver Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-96400-3_29

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