Abstract
Objectives: To evaluate the association between shift work with the risk of knee pain and knee osteoarthritis (KOA), we studied 13,906 retired workers from the Dongfeng-Tongji cohort.
Methods: Physical examinations and face-to-face interviews were performed. Knee pain was diagnosed by self-reported pain or stiffness. Clinical KOA was diagnosed from knee pain complains and clinical X-ray radiographs. Occupation history including work content and shift work experience in each job was collected from questionnaires.
Results: The prevalence of knee pain and clinical KOA was 39.0% and 6.7%, respectively. After adjusting for potential confounders, shift work was independently associated with elevated risk of knee pain (OR 1.24, 95% CI 1.15–1.33) and clinical KOA (1.15, 1.01–1.32). Such associations remained stable in stratified analyses by age, gender, BMI, work postures, or chronic diseases. Additionally, in comparison with daytime workers, the risks increased with prolonged duration of shift work, the ORs (95% CI) of knee pain for participants with 1–9 years, 10–19 years, and ≥20 years of shift work were 1.20 (1.08–1.33), 1.26 (1.14–1.40), and 1.26 (1.12–1.40), and ORs (95% CI) of clinical KOA were 1.06 (0.87–1.30), 1.15 (0.94–1.40), and 1.26 (1.02–1.56). However, the effects of shift work on knee gradually reduced with the extended duration of leaving shift work.
Conclusions: Shift work might be independent risk factor for knee pain and clinical KOA among the retired workers.
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References
Felson DT (2006) Clinical practice. osteoarthritis of the knee. N Engl J Med 354:841–848. https://doi.org/10.1056/NEJMcp051726
GBD 2016 DALYs and HALE Collaborators (2017) Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390:1260–1344. https://doi.org/10.1016/s0140-6736(17)32130-x
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017) Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390:1211–1259. https://doi.org/10.1016/s0140-6736(17)32154-2
Chopra A (2013) The COPCORD world of musculoskeletal pain and arthritis. Rheumatology 52:1925–1928. https://doi.org/10.1093/rheumatology/ket222
Fransen M, Bridgett L, March L, Hoy D, Penserga E, Brooks P (2011) The epidemiology of osteoarthritis in Asia. Int J Rheum Dis 14:113–121. https://doi.org/10.1111/j.1756-185X.2011.01608.x
Tang X, Wang S, Zhan S et al (2016) The prevalence of symptomatic knee osteoarthritis in China: results from the China health and retirement longitudinal study. Arthritis Rheumatol 68:648–653. https://doi.org/10.1002/art.39465
Agaliotis M, Fransen M, Bridgett L et al (2013) Risk factors associated with reduced work productivity among people with chronic knee pain. Osteoarthritis Cartilage 21:1160–1169. https://doi.org/10.1016/j.joca.2013.07.005
Palazzo C, Nguyen C, Lefevre-Colau MM, Rannou F, Poiraudeau S (2016) Risk factors and burden of osteoarthritis. Ann Phys Rehabil Med 59:134–138. https://doi.org/10.1016/j.rehab.2016.01.006
Spector JT, Adams D, Silverstein B (2011) Burden of work-related knee disorders in Washington State, 1999 to 2007. J Occup Environ Med 53:537–547. https://doi.org/10.1097/JOM.0b013e31821576ff
Haukka E, Ojajarvi A, Takala EP, Viikari-Juntura E, Leino-Arjas P (2012) Physical workload, leisure-time physical activity, obesity and smoking as predictors of multisite musculoskeletal pain. A 2-year prospective study of kitchen workers. Occup Environ Med 69:485–492. https://doi.org/10.1136/oemed-2011-100453
Solidaki E, Chatzi L, Bitsios P, Coggon D, Palmer KT, Kogevinas M (2013) Risk factors for new onset and persistence of multi-site musculoskeletal pain in a longitudinal study of workers in Crete. Occup Environ Med 70:29–34. https://doi.org/10.1136/oemed-2012-100689
Lau E, Cooper C, Lam D, Chan V, Tsang K, Sham A (2000) Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities. Am J Epidemiol 152:855–862
Pan A, Schernhammer ES, Sun Q, Hu FB (2011) Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. PLoS Med 8:e1001141. https://doi.org/10.1371/journal.pmed.1001141
De Bacquer D, Van Risseghem M, Clays E, Kittel F, De Backer G, Braeckman L (2009) Rotating shift work and the metabolic syndrome: a prospective study. Int J Epidemiol 38:848–854. https://doi.org/10.1093/ije/dyn360
Eurofound (2012) Working time and work–life balance in a life course perspective, Eurofound, Dublin
Linton SJ, Kecklund G, Franklin KA et al (2015) The effect of the work environment on future sleep disturbances: a systematic review. Sleep Med Rev 23:10–19. https://doi.org/10.1016/j.smrv.2014.10.010
Berenbaum F, Meng QJ (2016) The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond. Nat Rev Rheumatol 12:508–516. https://doi.org/10.1038/nrrheum.2016.93
Potter GD, Skene DJ, Arendt J, Cade JE, Grant PJ, Hardie LJ (2016) Circadian rhythm and sleep disruption: causes, metabolic consequences, and countermeasures. Endocr Rev 37:584–608. https://doi.org/10.1210/er.2016-1083
Zhou M, Guo Y, Wang D et al (2017) The cross-sectional and longitudinal effect of hyperlipidemia on knee osteoarthritis: results from the Dongfeng-Tongji cohort in China. Sci Rep 7:9739. https://doi.org/10.1038/s41598-017-10158-8
Wang F, Zhu J, Yao P et al (2013) Cohort Profile: the Dongfeng-Tongji cohort study of retired workers. Int J Epidemiol 42:731–740. https://doi.org/10.1093/ije/dys053
Jackson JL, O’Malley PG, Kroenke K (2003) Evaluation of acute knee pain in primary care. Ann Intern Med 139:575–588
Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494–502
Reijman M, Pols HA, Bergink AP et al (2007) Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam Study. Ann Rheum Dis 66:158–162. https://doi.org/10.1136/ard.2006.053538
Eymard F, Parsons C, Edwards MH et al (2015) Diabetes is a risk factor for knee osteoarthritis progression. Osteoarthritis Cartilage 23:851–859. https://doi.org/10.1016/j.joca.2015.01.013
Zhang Y, Hunter DJ, Nevitt MC et al (2004) Association of squatting with increased prevalence of radiographic tibiofemoral knee osteoarthritis: the beijing osteoarthritis study. Arthritis Rheum 50:1187–1192. https://doi.org/10.1002/art.20127
Takahashi M, Matsudaira K, Shimazu A (2015) Disabling low back pain associated with night shift duration: sleep problems as a potentiator. Am J Ind Med 58:1300–1310. https://doi.org/10.1002/ajim.22493
Lipscomb JA, Trinkoff AM, Geiger-Brown J, Brady B (2002) Work-schedule characteristics and reported musculoskeletal disorders of registered nurses. Scand J Work Environ Health 28:394–401
Choobineh A, Soltanzadeh A, Tabatabaee H, Jahangiri M, Khavaji S (2012) Health effects associated with shift work in 12-hour shift schedule among Iranian petrochemical employees. Int J Occup Saf Ergon 18:419–427. https://doi.org/10.1080/10803548.2012.11076937
Guo Y, Liu Y, Huang X et al (2013) The effects of shift work on sleeping quality, hypertension and diabetes in retired workers. PLoS ONE 8:e71107. https://doi.org/10.1371/journal.pone.0071107
Gumenyuk V, Howard R, Roth T, Korzyukov O, Drake CL (2014) Sleep loss, circadian mismatch, and abnormalities in reorienting of attention in night workers with shift work disorder. Sleep 37:545–556. https://doi.org/10.5665/sleep.3494
Gossan N, Zeef L, Hensman J et al (2013) The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis. Arthritis Rheum 65:2334–2345. https://doi.org/10.1002/art.38035
Dudek M, Meng QJ (2014) Running on time: the role of circadian clocks in the musculoskeletal system. Biochem J 463:1–8. https://doi.org/10.1042/bj20140700
McDearmon EL, Patel KN, Ko CH et al (2006) Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science 314:1304–1308. https://doi.org/10.1126/science.1132430
Scheer FA, Hilton MF, Mantzoros CS, Shea SA (2009) Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci USA 106:4453–4458. https://doi.org/10.1073/pnas.0808180106
Guo B, Yang N, Borysiewicz E et al (2015) Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway. Osteoarthritis Cartilage 23:1981–1988
Aspden RM, Scheven BA, Hutchison JD (2011) Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism. Lancet 357:1118–1120. https://doi.org/10.1016/s0140-6736(00)04264-1
Nea FM, Kearney J, Livingstone MB, Pourshahidi LK, Corish CA (2015) Dietary and lifestyle habits and the associated health risks in shift workers. Nutr Res Rev 28:143–166. https://doi.org/10.1017/s095442241500013x
Bonnell EK, Huggins CE, Huggins CT, McCaffrey TA, Palermo C, Bonham MP (2017) Influences on dietary choices during day versus night shift in shift workers: a mixed methods study. Nutrients 9:193. https://doi.org/10.3390/nu9030193
Lu B, Driban JB, Xu C, Lapane KL, McAlindon TE, Eaton CB (2017) Dietary fat intake and radiographic progression of knee osteoarthritis: data from the osteoarthritis initiative. Arthritis Care Res 69:368–375. https://doi.org/10.1002/acr.22952
Dai Z, Niu J, Zhang Y, Jacques P, Felson DT (2017) Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts. Ann Rheum Dis 76:1411–1419. https://doi.org/10.1136/annrheumdis-2016-210810
Acknowledgements
The authors are indebted to Dr. Stephen S. Bao at the Washington State Department of Labor and Industries for providing valuable comments. We also thank the study participants for their help. This work was supported by the National Natural Science Foundation of China [grant number 81573121]; and the Fundamental Research Funds for the Central Universities, Huazhong University of Science and Technology [grant number 2016JCTD116].
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Zhou, M., Wang, D., Guo, Y., Chen, W. (2019). Effects of Shift Work on Knee Pain and Knee Osteoarthritis Among Retired Chinese Workers. In: Bagnara, S., Tartaglia, R., Albolino, S., Alexander, T., Fujita, Y. (eds) Proceedings of the 20th Congress of the International Ergonomics Association (IEA 2018). IEA 2018. Advances in Intelligent Systems and Computing, vol 820. Springer, Cham. https://doi.org/10.1007/978-3-319-96083-8_6
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